Sep 13, 2026; Inglewood, California, USA;  Los Angeles Chargers quarterback Justin Herbert (10) looks downfield against the Arizona Cardinals during the fourth quarter at SoFi Stadium.  Mandatory Credit: Kiyoshi Mio-Imagn Images
IMAGN IMAGES via Reuters Connect

Las Vegas Raiders vs Los Angeles Chargers Prediction 9/20/2026 Today’s NFL Picks

Pick details

MATCHUP Las Vegas Raiders Los Angeles Chargers
Team Records 1-0 0-1
Spread +6.5 -102 -6.5 -118
Moneyline +245 -305
Total Over 43.5 (-105) Under 43.5 (-115)
Where SoFi Stadium, Inglewood, CA
When Sunday, September 20, 2026
Time 04:05 PM EDT
TV CBS

In this article, we will formulate a Raiders vs Chargers Prediction for this NFL Week 2 game on Sunday, September 20th. Let’s take a look at the prediction for this NFL matchup.

Los Angeles Chargers Preview


The Los Angeles Chargers have a 0-1 record and are coming off a 14-26 home defeat by the Arizona Cardinals, where they were outgained by their opponents 393-268 yards and had 51 total plays. Los Angeles had 187 passing yards, 81 rushing yards, and 17/27 completed passes, while losing the turnover battle by 2-0. The Chargers were 2/8 on third down conversions and 2/3 in the red zone.

Justin Herbert led Los Angeles with 17/27 passes, 209 passing yards, one touchdown, and one interception. Omarion Hampton had a team-high 43 rushing yards, while Ladd McConkey caught 5 passes for a team-high 82 receiving yards and 1 touchdown. Defensively, Derwin James Jr. led the Chargers with 10 total tackles, 7 of them solo, while Troy Dye had 0.5 sacks.

Las Vegas Raiders Preview


The Las Vegas Raiders have a 1-0 record and are coming off a 27-13 home victory over the Miami Dolphins, where they outgained their opponents 290-259 yards and had 67 total plays. Las Vegas had 160 passing yards, 130 rushing yards, and 21/30 completed passes, while the turnover battle was tied at 2-2. The Raiders were 5/13 on third down conversions and 3/4 in the red zone.

Kirk Cousins led Las Vegas with 21/30 passes, 160 passing yards, 3 touchdowns, and 2 interceptions. Ashton Jeanty had a team-high 102 rushing yards, while catching 6 passes for a team-high 45 receiving yards and 2 touchdowns. Defensively, Kwity Paye led the Raiders with 6 total tackles, 3 of them solo, adding 2 sacks.

Las Vegas Raiders @ Los Angeles Chargers Betting Trends: Week 2


Why the Los Angeles Chargers will win

  • The Raiders have lost each of their last nine games without Michael Mayer.
  • The Chargers have won each of their last seven September games against the Raiders.
  • The favorites have covered the spread in each of the last eight games between the Raiders and Chargers.
  • The Raiders have failed to cover the spread in each of their last five games as underdogs following a win.
  • The Raiders have lost the first quarter in each of their last three games against teams that held a losing record.
  • The Chargers have scored the first touchdown in nine of their last 10 Week 2 games.
  • The Chargers have won the first half in each of their last seven Week 2 games against AFC opponents.

Why the Las Vegas Raiders will win

  • The underdogs have won each of the Chargers’ last three games at SoFi Stadium.
  • The Chargers have lost seven of their last eight home games against opponents on a winning streak.
  • The Chargers have failed to cover the spread in each of their last four games.
  • The Raiders have covered the spread in each of their last four games against AFC opponents.
  • The Chargers have lost the first quarter in six of their last seven games as favorites against AFC opponents.
  • The road team has won the first half in seven of the Chargers’ last eight Week 2 games.

Total Points Facts

  • Each of the Raiders’ last seven road openers against AFC opponents have gone UNDER the total points line.
  • Each of the Chargers’ last six September games as favorites have gone UNDER the total points line.
  • Each of the last five games between AFC West teams have gone UNDER the total points line.

Los Angeles Chargers Player Prop Facts

  • Justin Herbert has recorded 227+ passing yards in 14 of the Chargers’ last 16 games as favorites following a home loss.
  • Omarion Hampton has scored a touchdown in four of his last five regular season appearances.
  • Justin Herbert has recorded 29+ rushing yards in each of his last four appearances.
  • Kimani Vidal has recorded 104+ rushing and receiving yards in four of his last five home appearances.
  • Kimani Vidal has recorded 10+ receiving yards in five of his last six home appearances.
  • Justin Herbert has recorded 21+ completions in 14 of the Chargers’ last 16 games as favorites following a home loss.
  • Heading into Week 2, Omarion Hampton ranks 1st in the NFL in broken tackles (6) this season.

Las Vegas Raiders Player Prop Facts

  • Tre Tucker has scored at least one touchdown in four of the Raiders’ last seven September games.
  • Kirk Cousins has recorded 221+ passing yards in each of his last seven September appearances with his team as an underdog.
  • Kirk Cousins has recorded 20+ completions in each of his last eight appearances with his team as an underdog on the West Coast.
  • Heading into Week 2, Kwity Paye ranks T1st in the NFL in sacks (2.0) this season.

Matchup/League Facts

  • Heading into Week 2, the Chargers rank T1st in the NFL in 4th down attempts (3) this season.
  • Heading into Week 2, the Chargers rank T1st in the NFL in 4th down percentage against (0.0%) this season.
  • Heading into Week 2, the Raiders rank 1st in the NFL in average kickoff return (47.5 yards) this season.
  • Heading into Week 2, the Raiders have recorded the equal-longest punt return this season (23 yards).

Raiders vs Chargers Prediction


In this Raiders vs Chargers Prediction, the Chargers are coming as -6.5 home favorites. Both teams are coming off opposite outcomes in their opening games of the season, with the Chargers losing at home in their opener and are looking to bounce back in front of their home crowd. They have won their last four meetings against the Raiders and have won and covered the spread in all five home meetings against the Raiders, so I like them in a bounce-back spot at home in this one. The Raiders won their season opener at home but they were terrible on the road last season with a 1-7 record. Take the Chargers and lay the -6.5 in this one.

Nikos Lagouretos's Pick: Los Angeles Chargers -6.5

Hot Cappers