Sep 29, 2025; Denver, Colorado, USA; Cincinnati Bengals wide receiver Ja'Marr Chase (1) looks on after the game against the Denver Broncos at Empower Field at Mile High. Mandatory Credit: Isaiah J. Downing-Imagn Images

Detroit Lions vs Cincinnati Bengals Prediction 10/5/2025 Today’s NFL Picks

Pick details

Detroit (3-1) vs Cincinnati (2-2)

October 5, 2025 at 04:25 PM EDT

The Line: Betting Odds: Cincinnati +8.5 — Over/Under: +48.5

(Get latest betting odds)

The Detroit Lions and Cincinnati Bengals meet Sunday in NFL action at Paycor Stadium. Here’s a Detroit Lions vs Cincinnati Bengals Prediction. This article will include a Detroit Lions vs Cincinnati Bengals Pick.

Detroit Lions Betting Preview


The Detroit Lions beat the Ravens and Browns, and play the Chiefs next. The Detroit Lions have won 6 of their last 7 regular season games. Jared Goff is completing 73.8 percent of his passes for 929 yards, 9 touchdowns, and 2 interceptions. Amon-Ra St. Brown and Jameson Williams have combined for 521 receiving yards and 7 touchdowns, while Sam LaPorta has 16 receptions.

The Detroit Lions ground game is averaging 139 yards per contest, and Jahmyr Gibbs leads the way with 271 yards and 4 touchdowns. Defensively, Detroit is allowing 22 points and 293 yards per game. Jack Campbell leads the Detroit Lions with 37 tackles, Aidan Hutchinson has 4 sacks and Kerby Joseph has 2 interceptions.

Cincinnati Bengals Betting Preview


The Cincinnati Bengals lost to the Vikings and Broncos, and they play the Packers next. The Cincinnati Bengals have won 7 of their last 9 games. Jake Browning is completing 64.3 percent of his passes for 506 yards, 3 touchdowns, and 5 interceptions. Ja’Marr Chase and Tee Higgins have combined for 400 receiving yards and 2 touchdowns, while Noah Fant has 12 receptions.

The Cincinnati Bengals ground game is averaging 50 yards per contest, and Chase Brown leads the way with 133 yards and 1 touchdown. Defensively, Cincinnati is allowing 29.8 points and 397.8 yards per game. Jordan Battle leads the Cincinnati Bengals with 32 tackles, Trey Hendrickson has 2 sacks and DJ Turner II has 1 interception.

Detroit Lions @ Cincinnati Bengals Betting Trends: Week 5


Why the Cincinnati Bengals will win

  • The Bengals have won each of their last seven Sunday games against the Lions.
  • The Lions have lost each of their last five Week 5 road games.
  • The Bengals have covered the spread in each of their last six games at Paycor Stadium when playing with a rest disadvantage.
  • The Lions have failed to cover the spread in each of their last three games as favorites following a home win.
  • The Bengals have won the first quarter in five of their last seven October games as underdogs.
  • The Bengals have won the first half in five of their last six games against the Lions.

Why the Detroit Lions will win

  • The Lions have won each of their last seven road games following a win.
  • The Bengals have lost each of their last four Sunday games against opponents on a winning streak.
  • The Lions have covered the spread in each of their last seven games as road favorites following a home win.
  • The Bengals have failed to cover the spread in five of their last six Sunday games as underdogs.
  • The Bengals have lost the first half in five of their last six games as underdogs against NFC opponents.

Total Points Facts


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  • Seven of the Bengals’ last eight home games have gone OVER the total points line.
  • Each of the Lions’ last three road games in October have gone OVER the total points line.

Cincinnati Bengals Player Prop Facts

  • Tee Higgins has scored at least one touchdown in each of his last five appearances at Paycor Stadium.
  • Ja’Marr Chase has recorded 77+ receiving yards in each of the Bengals’ last seven Sunday regular season games as home underdogs.
  • Samaje Perine has recorded 24+ rushing and receiving yards in each of his last six home appearances against NFC opponents.
  • Samaje Perine has recorded 17+ rushing yards in five of his last six appearances with the Bengals as underdogs.
  • Heading into Week 5, Ja’Marr Chase has recorded the most receptions in a single game this season (14 vs Jaguars, Week 2).

Detroit Lions Player Prop Facts

  • Jahmyr Gibbs has scored the first touchdown in three of the Lions’ last four games as favorites.
  • Jahmyr Gibbs has scored two touchdowns in each of the Lions’ last three games following a home win.
  • Jared Goff has recorded 240+ passing yards in each of his last six appearances with his team as a road favorite against AFC opponents.
  • Jahmyr Gibbs has recorded 63+ rushing yards in each of the Lions’ last eight Sunday games as road favorites.
  • Sam LaPorta has scored at least one touchdown in each of his last seven appearances with the Lions as favorites against teams on a losing streak.
  • Kalif Raymond has recorded 20+ receiving yards in each of the Lions’ last seven October road games.
  • Kalif Raymond has recorded 14+ rushing and receiving yards in each of the Lions’ last 11 October games.
  • Jared Goff has recorded 21+ completions in nine of the Lions’ last 10 regular season games as favorites.
  • Heading into Week 5, Amon-Ra St. Brown ranks 1st in the NFL in receiving touchdowns (6) this season.

Matchup/League Facts

  • Heading into Week 5, the Bengals rank 1st in the NFL in total punt yards (1213) this season.
  • Heading into Week 5, the Bengals rank 32nd in the NFL in time of possession per game (25:32) this season.
  • Lions – one different players have recorded 100+ rushing yards in a game this season – equal-most in the NFL, heading into Week 5.
  • Lions – two different players have recorded 100+ receiving yards in a game this season – equal-most in the NFL, heading into Week 5.

Detroit Lions vs Cincinnati Bengals Prediction


This is a thick line for a road team, but the Lions offense that’s first in scoring should have a field day against this Bengals’ defense that looks like last year’s squad. The Bengals can’t get stops, and the offense is extremely limited with Browning at quarterback. Chase was losing it on the sidelines in their last effort. The Bengals also have less time to prepare, which doesn’t help. The Lions have covered 5 of their last 6 games as a favorite. The Bengals have failed to cover 8 of their last 12 games as an underdog. This has the potential to get ugly. Even on the road, give me the Lions in a double-digit victory.

Randy Chambers's Pick: Detroit Lions -8.5

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