Pick details
| MATCHUP | Indianapolis Colts | Minnesota Vikings |
|---|---|---|
| Team Records | 2-4 | 5-0 |
| Spread | +6.5 -112 | -6.5 -108 |
| Moneyline | +225 | -278 |
| Total | Over 41.5 (-110) | Under 41.5 (-110) |
| Where | U.S. Bank Stadium, Minneapolis, MN | |
| When | Sunday, October 25, 2026 | |
| Time | 01:00 PM EDT | |
| TV | CBS | |
In this article, we will formulate a Colts vs Vikings Prediction for this NFL Week 6 game on Sunday, October 25th. Let’s take a look at the prediction for this NFL matchup.
Minnesota Vikings Preview
The Minnesota Vikings have a 5-0 record this season are sitting on the 1st place of the NFC North. They are coming off a 23-13 road win against the Saints and will face the Lions, the Bills and the Packers next.
Offensively, the Vikings average 21.8 points per game, ranking 22nd in the NFL, while defensively, they allow 12.8 points per game, which is 1st. Minnesota averages 283 total yards per game (167 passing and 116 rushing), while allowing 259.8 total yards per game (86.6 rushing and 173.2 passing).
Kyler Murray leads the Vikings with 662 passing yards with 68.3% completed passes and two touchdowns. Aaron Jones leads the team in rushing yards with 410, while Justin Jefferson has 19 receptions for a team-high 258 receiving yards. Defensively, Blake Cashman has a team-high 42 total tackles (22 of them solo), while Dallas Turner leads the team in sacks, with 5.5.
Indianapolis Colts Preview
The Indianapolis Colts have a 2-4 record this season are sitting on the 2nd place of the AFC South. They are coming off a 20-26 home loss against the Titans and will face the Jaguars, the Cowboys and the Dolphins next.
Offensively, the Colts average 24 points per game, ranking 14th in the NFL, while defensively, they allow 27.3 points per game, which is 27th. Indianapolis averages 311.3 total yards per game (199.8 passing and 111.5 rushing), while allowing 351.2 total yards per game (122.5 rushing and 228.7 passing).
Daniel Jones leads the Colts with 1290 passing yards with 59.6% completed passes and four touchdowns. Jonathan Taylor leads the team in rushing yards with 492, while Josh Downs has 24 receptions for a team-high 289 receiving yards. Defensively, Akeem Davis-Gaither has a team-high 53 total tackles (28 of them solo), while DeForest Buckner leads the team in sacks, with 4.
Colts vs Vikings Prediction
In this Colts vs Vikings Prediction, the Vikings are coming as -6.5 home favorites. Let’s do not overthink this one. The Vikings have been undefeated this season, they are 4-1 against the spread and have the best defense in football, while on the other hand, the Colts have lost and failed to cover their last two games and have lost two of their three road game this season, having allowed 33 and 34 points in two of those. The Vikings have won their last two head-to-head meetings against the Colts, both in Minnesota, so I like them to win and cover the spread today.
