Jacksonville Jaguars vs Indianapolis Colts Prediction NFL Picks 1/5/25
Indianapolis Colts (7-9) vs Jacksonville Jaguars (4-12)
Game Info: Sunday, January 5, 2025 at 1:00 pm (Lucas Oil Stadium)
Betting Odds: Indianapolis Colts -5 / Jacksonville Jaguars +5 --- Over/Under: 45.5 Click Here for the Latest Odds
Where to Watch: FOX
The Jacksonville Jaguars and the Indianapolis Colts meet in week 18 NFL action from Lucas Oil Stadium on Sunday afternoon. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Jacksonville Jaguars vs. Indianapolis Colts prediction.
Jacksonville Jaguars Recap
The Jacksonville Jaguars come into this game looking to compete while not hurting their draft stock, sitting at 4-12 on the year after a 20-13 win over Tennessee last time out. The Jaguars will miss the playoffs for the second straight year while finishing with their first losing season since 2021.
Jaguars Playing Out The String
Mac Jones has thrown for 1,447 yards, 7 touchdowns, and 7 interceptions on 65.7% passing while Tank Bigsby has rushed for a team-high 727 yards and 6 TDs and Travis Etienne Jr. has 527 rushing yards. Brian Thomas Jr. has a team-high 1,179 receiving yards along with 10 TDs while another four Jaguars have 350+ receiving yards as well on the year. Devin Lloyd leads the Jaguars’ defense with 107 total tackles while Travon Walker has a team-high 9.5 sacks and Josh Hines-Allen has 8 sacks. As a unit, Jacksonville’s defense has combined for 31 sacks and 6 interceptions.
Why the Jacksonville Jaguars will win
- The Colts have lost each of their last six games in January.
- The Jaguars have won each of their last two games as road underdogs following a Division win.
- The Jaguars have covered the spread in seven of their last eight January games as underdogs against AFC opponents.
- The Colts have failed to cover the spread in seven of their last eight games in January.
Indianapolis Colts Recap
The Indianapolis Colts come into this one looking to finish the season on a high note after taking one on the chin in a 45-33 loss to the New York Giants to fall to 7-9 and eliminate any hopes of the Colts making the postseason. As a result, the Colts will miss the playoffs for the fourth straight year.
Colts Looking To Salvage Win In Finale
Anthony Richardson has thrown for 1,814 yards, 8 touchdowns, and 12 interceptions on 47.7% passing while also rushing for 499 yards and 6 TDs. Joe Flacco has thrown for 1,497 yards, 11 TDs, and 7 interceptions on 66.8% passing. Jonathan Taylor has a team-high 1,254 rushing yards and 10 TDs while Josh Downs has 62 receptions for 709 yards and 5 touchdowns. Alec Pierce has 767 receiving yards along with 6 TDs and Michael Pittman Jr. has 63 grabs for 736 yards. Adonai Mitchell has 312 receiving yards and another three receivers have 100+ receiving yards. On defense, Zaire Franklin has a team-high 165 total tackles. Kwity Paye has a team-high 7 sacks DeForest Buckner has 6.5 sacks and Laiatu Latu has 4 sacks as well on the year. As a team, the Colts’ defense has put up 34 sacks and 15 interceptions so far this season.
Why the Indianapolis Colts will win
- The favorites have won each of the Jaguars' last 11 games at Lucas Oil Stadium.
- The Jaguars have lost 11 of their last 13 road games against teams that held a losing record.
- The Colts have covered the spread in each of their last five games against AFC South opponents.
- The Jaguars have failed to cover the spread in each of their last five games following a win.
Total Points Facts
- Seven of the Jaguars' last eight January games against AFC South opponents have gone UNDER the total points line.
- Seven of the Colts' last eight games at Lucas Oil Stadium following a loss have gone OVER the total points line.
- Four of the last five games between teams from the same division have gone OVER the total points line.
Jaguars vs. Colts Prediction
I’m going to lean towards the Colts here. There are much better opportunities on Sunday’s card. Still, I’m only operating under the assumption that Jacksonville would rather take the L and not hurt their draft stock with the logjam of 4-12 teams between the bottom 10 in the draft order. I think the Colts would like to get the bad taste out of their mouths at home and give their fans a proper sending-off after an abysmal showing against a bad Giants team last week. Give me the Colts if forced to bet on this one.
Chris’s Pick Indianapolis -5
AUTHOR: Chris Ruffolo

Follow Chris Ruffolo on Twitter @ruffthepickdawg