St. Louis Cardinals vs Philadelphia Phillies Prediction 5/13/25 MLB Picks

The St. Louis Cardinals and the Philadelphia Phillies meet Tuesday in MLB action from Citizens Bank Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a St. Louis Cardinals vs. Philadelphia Phillies prediction.

Starting Pitching Matchup

The St. Louis Cardinals will send out Sonny Gray for the start here, and Gray is 4-1 with a 3.50 ERA and 47 strikeouts this season. In his last five starts against the Phillies, Gray is 2-2 with a 3.55 ERA and 32 strikeouts. Jesus Luzardo will get the start for the Phillies and is 3-0 with a 2.11 ERA and 51 strikeouts this season. In his career, Luzardo is 1-1 with a 3.77 ERA and 13 strikeouts against the Cardinals.

St. Louis Cardinals Recap

The St. Louis Cardinals come into this game looking to build on their 3-2 win over the Phillies in Monday’s series opener to improve to 23-19 on the year. After this series, the Cardinals will head on the road for a series against the Kansas City Royals.

Cardinals Pick Up 9th Straight Win

Brendan Donovan has a team-high 48 hits along with 12 doubles, 3 home runs, and 19 RBIs, while Lars Nootbaar has 26 hits with 4 home runs, 17 RBIs, and 3 stolen bases. Nolan Arenado also has 38 hits with 9 doubles, 6 home runs, and 22 RBIs of his own, and Victor Scott II has 36 hits with 6 doubles, a triple, 8 RBIs, and a team-high 11 stolen bases. Willson Contreras has also chipped in 38 hits with 6 home runs and 23 RBIs of his own this season.

Why the St. Louis Cardinals will win

• The Cardinals have won each of their last nine games.
• The Cardinals have covered the run line in each of their last nine games.
• The Phillies have failed to cover the run line in four of their last five games at Citizens Bank Park.

St. Louis Cardinals Player Prop Facts

• Willson Contreras has hit a home run in two of the Cardinals’ last three games as road underdogs.
• Willson Contreras has recorded a Double in three of his last four appearances against the Phillies after playing the previous day.
• Willson Contreras has recorded at least one RBI in four of the Cardinals’ last five games as underdogs against NL East opponents.
• Masyn Winn has scored at least one run in 10 of his last 11 appearances in night games against NL teams that held a winning record.
• Sonny Gray has recorded six or more strikeouts in each of his last nine road appearances against opponents that held a winning record.
• Brendan Donovan has recorded at least one Single in nine of his last 10 appearances in night games against NL East teams that held a winning record.
• Willson Contreras has recorded at least one hit in each of the Cardinals’ last 11 games as underdogs against NL East opponents.
• Sonny Gray ranks T10th in the league for Wins (4) this season.

Philadelphia Phillies Recap

The Philadelphia Phillies will be out to bounce back from their loss at the hands of the Cardinals in Monday’s series opener to fall to 24-17 on the year. After this series, the Phillies will square off against the Pittsburgh Pirates at home.

Phillies Still Win 7 Of Their Last 10 Despite Monday’s Loss

Nick Castellanos has 42 hits with 10 doubles, including 4 home runs and 21 RBIs, while Kyle Schwarber has 39 hits with a team-high 14 home runs and 32 RBIs as well on the year. Bryce Harper has 6 stolen bases, 7 home runs, and 22 RBIs. Trea Turner also has 48 hits with a team-high 9 stolen bases. Max Kepler has 8 doubles and Bryson Stott has 5 doubles, 2 triples, 3 homers, and 20 RBIs, while Stott also has 8 stolen bases this season.

Why the Philadelphia Phillies will win

• The Phillies have won each of their last 13 home games against National League opponents following a home loss.
• The Cardinals have lost nine of their last 10 games against the Phillies following a road win.
• The Cardinals have failed to cover the run line in seven of their last eight night games against the Phillies at Citizens Bank Park following a win.
• The Phillies have covered the run line in each of their last four home games against the Cardinals following a loss.

Philadelphia Phillies Player Prop Facts

• Nick Castellanos has recorded a Double in three of the Phillies’ last four night games against NL Central opponents that held a winning record.
• Kyle Schwarber has hit a home run in four of the Phillies’ last seven games as home favorites.
• J.T. Realmuto has recorded at least one RBI in each of his last four home appearances after playing the previous day.
• Kyle Schwarber has scored a run in nine of the Phillies’ last 10 home games against opponents that held a winning record.
• Jesus Luzardo has recorded six or more strikeouts in eight of his last nine appearances with his team as a home favorite against NL opponents.
• Trea Turner has recorded at least one Single in each of the Phillies’ last eight games against NL opponents that held a winning record.
• Nick Castellanos has recorded at least one hit in each of his last 11 appearances with his team as a home favorite against the Cardinals.
• Kyle Schwarber ranks T1st in the league in Home Runs (14) this season.

Total Runs Facts

• Nine of the last 10 games between the Cardinals and Phillies have gone UNDER the total runs line.
• Eight of the Cardinals’ last nine games as underdogs against the Phillies have gone UNDER the total runs line.

St. Louis Cardinals vs. Philadelphia Phillies Prediction

I’m going to take a shot on the Cardinals here. It’s not a game I’m rushing to the window to bet, but the Cardinals are white hot right now, and Gray is a solid starting option for the Cardinals as well. Luzardo is a solid lefty, emerging as one of the better southpaws in baseball, but the thing is that the Phillies behind him have been inconsistent, and I still have a hard time trusting this Phillies bullpen. Give me the Cardinals and the plus money here.

Chris Ruffolo's Pick: St. Louis Cardinals +130