St. Louis Cardinals vs Minnesota Twins Prediction 6/13/2026 Today’s MLB Picks

The St. Louis Cardinals and the Minnesota Twins meet Saturday in MLB action from Target Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s a St. Louis Cardinals vs. Minnesota Twins prediction.

Starting Pitching Matchup

The St. Louis Cardinals will send out Matthew Liberatore for the start here and Liberatore is 3-3 with a 4.48 ERA and 61 strikeouts this season. Connor Prielipp will start for Minnesota and is 2-4 with a 5.15 ERA and 49 strikeouts this season. 

St. Louis Cardinals Recap

The St. Louis Cardinals come into this game looking to rebound from a 9-8 loss at the hands of the Twins on Friday to sit at 37-30 this season. After this series, the Cardinals will head home for a series against the San Diego Padres.

Cardinals Drop Back-To-Back Games

Going into Friday, Jordan Walker leads the Cardinals with 77 hits, 15 doubles, 17 home runs and 52 RBIs while Alec Burleson has 74 hits with 17 doubles, 11 home runs and 48 RBIs. JJ Wetherholt has 60 hits with 9 home runs and 27 RBIs while Ivan Herrera has 64 hits with 13 doubles, 7 home runs and 28 RBIs. Nolan Gorman has 39 hits with 7 home runs and 26 RBIs this season. Masyn Winn’s added 51 hits with 9 doubles and 22 RBIs and Nathan Church has 40 hits with 5 home runs and 18 RBIs this season. 

Minnesota Twins Recap

The Minnesota Twins come into this game looking to add on to their win over the Cards from Friday’s matchup to improve to 32-39 on the year. After this series, the Twins will head on the road for a game against the Texas Rangers.

Twins Looking To Build Momentum

Entering Friday, Byron Buxton has 61 hits with 10 doubles, a triple, 20 home runs and 32 RBIs while Josh Bell’s added 56 hits with 12 doubles, 7 home runs and 38 RBIs. Luke Keaschall has 56 hits with 10 doubles, a homer and 21 RBIs. Brooks Lee has 10 home runs with 38 RBIs and Victor Caratini has 23 RBIs while Kody Clemens has 48 hits with 14 doubles, 2 triples, 9 home runs and 21 RBIs this season.

St. Louis Cardinals @ Minnesota Twins Betting Trends: June 13, 2026

• Probable Starting Pitcher: Connor Prielipp      Record this season: 2-4      ERA: 5.15
• Home Record: 2-2
• Last 5 against Cardinals: –

Why the Minnesota Twins will win

• The home team has won each of the last four games between the Cardinals and Twins.
• The Cardinals have lost four of their last five games against American League opponents.
• The Twins have covered the run line in four of their last five home games against National League opponents.
• The Cardinals have failed to cover the run line in five of their last six day games against AL Central opponents following a loss.
• The Cardinals have lost the first inning in three of their last four day games against AL Central opponents.
• The Twins have led after 5 innings in each of their last four day games at Target Field against National League opponents.

• Probable Starting Pitcher: Matthew Liberatore      Record this season: 3-3      ERA: 4.48
• Road Record: 1-2
• Last 5 against Twins: 0-1

Why the St. Louis Cardinals will win

• The Twins have lost each of their last eight day games after playing the previous day.
• The Cardinals have won five of their last six games against the Twins following a loss.
• The Cardinals have covered the run line each of their last six games against teams that held a losing record.
• The Twins have failed to cover the run line in each of their last five games against the Cardinals following a win.
• The Twins have lost the first inning in three of their last four day games.
• The Twins have trailed after 5 innings in eight of their last nine day games.
• The Twins have trailed after 3 innings in seven of their last eight day games.

Total Runs Facts

• Each of the Twins’ last seven day games against National League opponents have gone OVER the total runs line.
• Each of the Cardinals’ last four day games against American League opponents have gone UNDER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the last five games between the Cardinals and Twins.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Cardinals’ last four day games against AL Central opponents.

Minnesota Twins Player Prop Facts

• Byron Buxton has hit a home run in three of the Twins’ last four games.
• Josh Bell has recorded at least one hit in each of the Twins’ last eight games against opponents that held a winning record.
• Byron Buxton ranks 3rd in the league in Home Runs (21) this season.

St. Louis Cardinals Player Prop Facts

• Alec Burleson has hit a home run in each of the Cardinals’ last four games.
• Masyn Winn has recorded at least one hit in each of his last eight road appearances against AL opponents.
• Jordan Walker is one of only three players to hit over .300 and have 45+ RBIs this season.

Matchup/League Facts

• The Twins rank 28th in the league for ERA this season (4.81).
• The Twins rank 28th in the league for runs allowed this season (367).
• The Cardinals rank T28th in the league for triples this season (5).
• The Cardinals rank 28th in the league for strikeouts this season (518).

St. Louis Cardinals vs. Minnesota Twins Prediction

I’m on the Cardinals here. The Twins were lucky to escape with one on Friday, but get a tough draw here. Matthew Liberatore isn’t my favorite arm in this Cardinal rotation, but he’s a lefty and the Twins have really struggled against lefties in recent weeks. The Cards on the other hand have excelled against lefties and Connor Prielipp’s been struggling in recent starts after a strong start to his campaign. Give me St. Louis for the bounce back.

Chris Ruffolo's Pick: St. Louis +125