St. Louis Cardinals vs Colorado Rockies Prediction 9/5/2026 Today’s MLB Picks

The St. Louis Cardinals and the Colorado Rockies meet Saturday in MLB action from Coors Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s a St. Louis Cardinals vs. Colorado Rockies prediction.

Starting Pitching Matchup

The St. Louis Cardinals will send out Matthew Liberatore here and Liberatore is 5-13 with a 5.41 ERA and 141 strikeouts this season. Mason Adams will start for the Rockies and is 0-0 with a 3.00 ERA and 10 strikeouts this season.

St. Louis Cardinals Recap

The St. Louis Cardinals come into this game looking to build on their 7-6 win over the Rockies from Friday’s matchup to sit at 71-71 this season. After this series, the Cardinals will head on the road for a series against the San Francisco Giants.

Cardinals Win 3 Of Last 4 Games

Jordan Walker has 156 hits, 32 doubles, 28 home runs and 100 RBIs while Alec Burleson has 151 hits with 33 doubles, 21 home runs and 102 RBIs. JJ Wetherholt has 122 hits with 17 home runs and 48 RBIs while Ivan Herrera has 131 hits with 24 doubles, 15 home runs and 59 RBIs. Masyn Winn’s added 103 hits with 19 doubles and 51 RBIs and Nathan Church has 89 hits with 10 home runs and 47 RBIs this season. 

Colorado Rockies Recap

The Colorado Rockies come into this game looking to bounce back from their loss at the hands of the Cardinals to sit at 54-87 this season. After this series, the Rockies will head on the road for a series against the New York Yankees.

Rockies Lose 6 Of Last 8

TJ Rumfield has 142 hits with 26 doubles, 2 triples, 15 home runs and 65 RBIs while Ezequiel Tovar has 87  hits with 21 doubles, 10 home runs and 41 RBIs. Hunter Goodman’s added 113 hits with 18 doubles, 36 home runs and 74 RBIs. Troy Johnston has 103 hits with 29 doubles, 4 home runs and 47 RBIs. Willi Castro also has 111 hits with 20 doubles, 15 home runs and 56 RBIs. Jake McCarthy also has 134 hits with 29 doubles, 8 triples, 14 home runs and 72 RBIs.

St. Louis Cardinals @ Colorado Rockies Betting Trends: September 5, 2026

• Probable Starting Pitcher: Mason Adams      Record this season: 0-0      ERA: 3.00
• Home Record: 0-0
• Last 5 against Cardinals: –

Why the Colorado Rockies will win

• The Cardinals have lost four of their last five games as road favorites against NL West opponents following a road win.
• The Rockies have won each of their last three games as home underdogs against NL Central opponents following a loss.
• The Cardinals have failed to cover the run line in each of their last 17 games as favorites against NL West opponents following a win.
• The underdogs have covered the run line in each of the Cardinals’ last 10 games.
• The Cardinals have trailed after 5 innings in three of their last four games as road favorites against NL West opponents.
• The Cardinals have trailed after 3 innings in each of their last seven Saturday games against NL West opponents that held a losing record.

• Probable Starting Pitcher: Matthew Liberatore      Record this season: 5-13      ERA: 5.41
• Road Record: 2-7
• Last 5 against Rockies: 0-2

Why the St. Louis Cardinals will win

• The Rockies have lost seven of their last eight home games against NL opponents.
• The road team has won five of the Cardinals’ last six games.
• The Cardinals have covered the run line in each of their last five night games following a win.
• The Rockies have failed to cover the run line in three of their last four home games against NL opponents after playing the previous day.
• The Cardinals have led after 5 innings in each of their last seven games as road favorites.
• The Rockies have trailed after 3 innings in five of their last six games against NL opponents.

Total Runs Facts

• Each of the Rockies’ last six home games after playing the previous day have gone UNDER the total runs line.
• Eight of the Cardinals’ last nine road games have gone OVER the total runs line.
• There has been at least one run scored in the first inning in seven of the Cardinals’ last eight road games.
• There has been no run scored during the first inning in seven of the Rockies’ last eight night games.

Colorado Rockies Player Prop Facts

• TJ Rumfield has hit a home run in three of the Rockies’ last four games as home underdogs against NL Central opponents.
• TJ Rumfield has recorded at least one hit in each of the Rockies’ last nine games.

St. Louis Cardinals Player Prop Facts

• Ivan Herrera has hit a home run in three of the Cardinals’ last four road games against NL West opponents that held a losing record.
• Matthew Liberatore has recorded six or more strikeouts in each of his last four appearances.
• Jordan Walker has recorded at least one hit in each of the Cardinals’ last 13 games against NL West opponents.

Matchup/League Facts

• The Rockies rank 30th in the league for strikeouts this season (958).
• The Rockies rank 30th in the league for opponent batting average this season (.286).
• The Cardinals rank 26th in the league for slugging percentage this season (.385).
• The Cardinals rank 26th in the league for opponent batting average this season (.254).

St. Louis Cardinals vs. Colorado Rockies Prediction

I’m on the over in this one. I get the case to be made for either side here, but these are two questionable options for their respective rotations. Liberatore’s had issues keeping runs off of the board this season and Adams is a solid pitcher that has upside, but he has the disservice of pitching at Coors Field and I think this St. Louis offense that has momentum after rallying on Friday can put up enough to get us up and over this total. Give me the over.

Chris Ruffolo's Pick: Over 11