St. Louis Cardinals vs Athletics Prediction 5/13/2026 Today’s MLB Picks

The St. Louis Cardinals and the Athletics meet Wednesday in MLB action from Sutter Health Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a St. Louis Cardinals vs. Athletics prediction.

Starting Pitching Matchup

The St. Louis Cardinals will send out Matthew Liberatore for the start here and Liberatore is 2-1 with a 4.07 ERA and 29 strikeouts this season. In his career, Liberatore is 1-1 with a 4.66 ERA and 12 strikeouts against the Athletics. JT Ginn will start for the Athletics here and is 1-1 with a 3.62 ERA and 31 strikeouts this season. This will be Ginn’s first career start against the Cardinals.

St. Louis Cardinals Recap

The St. Louis Cardinals come into this game looking to add on to their 6-4 win over the Athletics from Tuesday’s matchup to sit at 24-17 this season. After this series, the Cardinals will head home for a series against the Kansas City Royals.

Cardinals Snap Two-Game Slide

Going into Tuesday, Jordan Walker leads the Cardinals with 44 hits, 8 doubles, 11 home runs and 29 RBIs while Alec Burleson has 41 hits with 10 doubles, 6 home runs and 30 RBIs. JJ Wetherholt has 36 hits with 7 home runs and 20 RBIs while Ivan Herrera has 38 hits with 11 doubles, 4 home runs and 18 RBIs. Nolan Gorman has 29 hits with 5 home runs and 22 RBIs this season. Masyn Winn’s added 33 hits with 6 doubles and 16 RBIs and Nathan Church has 29 hits with 5 home runs and 17 RBIs this season. 

Athletics Recap

The Athletics come into this game looking to bounce back from a loss to St. Louis on Tuesday to fall to 21-20 this season. After this series, the Athletics will take on the San Francisco Giants in a series at home.

Athletics Drop Back-To-Back Games

Entering Tuesday, Shea Langeliers has 50 hits with 9 doubles, 11 home runs and 22 RBIs while Tyler Soderstrom’s added 30 hits with 12 doubles, a triple, 5 home runs and 20 RBIs. Brent Rooker has 17 hits with 5 home runs and 18 RBIs while Max Muncy has also chipped in 22 hits with 5 doubles, 2 triples, 2 home runs and 7 RBIs this season. Jacob Wilson also has 47 hits with 8 doubles, 3 home runs and 19 RBIs and Nick Kurtz has 37 hits with 7 doubles, 5 home runs and 20 RBIs this season.

St. Louis Cardinals @ Athletics Betting Trends: May 13, 2026

• Probable Starting Pitcher: J.T. Ginn      Record this season: 1-1      ERA: 3.62
• Home Record: 0-1
• Last 5 against Cardinals: –

Why the Athletics will win

• The Cardinals have lost five of their last six night games against AL West opponents that held a winning record.
• The Athletics have won four of their last five games following a home loss.
• The Athletics have covered the run line in each of their last four games after playing the previous day.
• The Cardinals have failed to cover the run line in five of their last six night games against AL West opponents that held a winning record.
• The Athletics have led after 5 innings in three of their last four night games.
• The Athletics have led after 3 innings in four of their last five games against opponents that held a winning record.

• Probable Starting Pitcher: Matthew Liberatore      Record this season: 2-1      ERA: 4.07
• Road Record: 1-0
• Last 5 against Athletics: 1-1

Why the St. Louis Cardinals will win

• The Cardinals have won each of their last 10 night games against teams that held a winning record.
• The Athletics have lost each of their last eight Wednesday games against National League opponents.
• The Cardinals have covered the run line each of their last 10 night games against teams that held a winning record.
• The Athletics have failed to cover the run line in each of their last eight Wednesday games against National League opponents.
• The Athletics have lost the first inning in four of their last five games against NL Central opponents.
• The Cardinals have led after 5 innings in seven of their last eight night games.
• The Athletics have trailed after 3 innings in each of their last five games against NL Central opponents.

Total Runs Facts

• Seven of the Athletics’ last eight games as favorites against National League opponents have gone UNDER the total runs line.
• Each of the Cardinals’ last four games after playing the previous day have gone UNDER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in 12 of the Athletics’ last 13 games as home favorites.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in five of Matthew Liberatore’s last six appearances as a starter.

Athletics Player Prop Facts

• Shea Langeliers has hit at least one home run in each of his last three home appearances against opponents that held a winning record.
• Zack Gelof has recorded at least one hit in each of his last seven appearances after playing the previous day.
• Shea Langeliers ranks 2nd in the league in Hits (52) this season.

St. Louis Cardinals Player Prop Facts

• Alec Burleson has hit a home run in three of the Cardinals’ last six road games against AL opponents that held a winning record.
• Lars Nootbaar has recorded at least one hit in each of his last seven appearances in night games against teams that held a winning record.
• Jordan Walker ranks 9th amongst qualified players for Slugging Percentage (.570) this season.

Matchup/League Facts

• The Athletics rank 26th in the league for walks allowed this season (178).
• The Athletics rank 7th in the league for slugging percentage this season (.399).
• The Cardinals rank 30th in the league for strikeouts this season (298).
• The Cardinals rank T27th in the league for triples this season (2).

St. Louis Cardinals vs. Athletics Prediction

I’m on the Athletics here. I just think this is a spot for the Athletics to bounce back Liberatore has been very profitable this season but he’s been backed up a lot by the Cardinals as a unit and I think this could be a situation where the Athletics bats are too much for Liberatore to hld down here. Ultimately it should be a great game but I like the A’s for the bounce back here.

Chris Ruffolo's Pick: Athletics -140