Jul 18, 2025; Washington, District of Columbia, USA; San Diego Padres first baseman Luis Arraez (4) tosses a fielded ground ball to first base against the Washington Nationals during the third inning at Nationals Park. Mandatory Credit: Geoff Burke-Imagn Images

San Diego Padres vs Washington Nationals Prediction 07/19/2025 Picks

Pick details

San Diego (53-44) vs Washington (38-59)

July 19, 2025 at 06:45 PM EDT

The Line: Betting Odds: Washington +1.5 — Over/Under: +9

(Get latest betting odds)


The San Diego Padres and Washington Nationals meet Saturday in MLB action at Nationals Park. Here’s a San Diego Padres vs Washington Nationals Prediction. This article will include a San Diego Padres vs Washington Nationals Pick.

San Diego Padres Betting Preview

The San Diego Padres are 53-44 on the year and play the Marlins, Cardinals, and Mets next. The San Diego Padres are batting .246 on the season, have a .316 OBP, and a .375 slugging percentage. The San Diego Padres pitching staff has a 3.63 ERA and a 1.24 WHIP. Manny Machado leads the San Diego Padres with 108 hits and 60 RBI, while Luis Arraez and Fernando Tatis Jr. have combined for 201 hits and 77 RBI. 

Yu Darvish gets the ball for the San Diego Padres, and he is 0-1 with a 6.48 ERA and 7 strikeouts this season. Darvish is 2-2 with a 4.60 ERA and 33 strikeouts in his career against the Washington Nationals.

Washington Nationals Betting Preview

The Washington Nationals are 38-59 on the year and play the Reds, Twins, and Astros next. The Washington Nationals are batting .245 on the season, have a .311 OBP, and a .389 slugging percentage. The Washington Nationals’ pitching staff has a 5.23 ERA and a 1.41 WHIP. James Wood leads the Washington Nationals with 99 hits and 69 RBI, while CJ Abrams and Nathaniel Lowe have combined for 180 hits and 96 RBI.

Mitchell Parker gets the ball for the Washington Nationals, and he is 5-10 with a 5.12 ERA and 66 strikeouts this season. Parker is 1-1 with a 9.00 ERA and 6 strikeouts in his career against the San Diego Padres.

Why the Washington Nationals will win

The Padres have lost each of their last seven games following a road win.
The Nationals have won each of their last five Saturday games as home underdogs against NL West opponents.
The Padres have failed to cover the run line in each of their last eight games as favorites against National League opponents following a win.
The Nationals have covered the run line in each of their last 10 Saturday night games as underdogs against NL West opponents.

Why the San Diego Padres will win

The Padres have won nine of their last 10 games against the Nationals.
The Nationals have lost eight of their last nine games against National League opponents.
The Nationals have failed to cover the run line in each of their last eight home games against National League opponents after playing the previous day.
The Padres have covered the run line in seven of their last eight games at Nationals Park against teams that held a losing record.
The Padres have led after 5 innings in each of their last five games at Nationals Park against National League opponents that held a losing record.
The Padres have led after 3 innings in each of their last six Saturday night games as road favorites.

Washington Nationals Player Prop Facts

Amed Rosario has recorded a Double in three of his last four home appearances against NL West opponents that held a winning record.
Amed Rosario has hit a home run in two of his last three appearances in night games against NL teams that held a winning record.
Amed Rosario has recorded at least one hit in 15 of his last 16 appearances at Nationals Park against NL opponents that held a winning record.

San Diego Padres Player Prop Facts

Yu Darvish has recorded five or more strikeouts in each of his last 15 Saturday appearances with his team as a favorite.
Yu Darvish has recorded a win in each of his last four road appearances against NL opponents that held a losing record.
Manny Machado has hit a home run in three of the Padres’ last four road games against opponents that held a losing record.
Manny Machado has recorded at least one hit in each of the Padres’ last 10 road games against NL opponents that held a losing record.

San Diego Padres vs Washington Nationals Prediction

Darvish has just 8.1 innings under his belt this season, but he’s an accomplished veteran who will figure things out with more reps. The Nationals continue to pile up the losses, and Parker has been a mess for much of the season. In his last 15.2 innings, Parker has allowed 24 hits and 14 earned runs. The Nationals have lost seven of the last nine games Parker has pitched. Even with a small sample size, I have to lean toward the Padres. Darvish will settle in with more innings under his belt. 

Randy Chambers's Pick: San Diego Padres

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