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Pittsburgh Pirates vs Philadelphia Phillies Prediction 5/17/25 MLB Picks

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Philadelphia Phillies (26-18) vs Pittsburgh Pirates (15-30)

May 17, 2025 at 06:05 PM EDT

The Line: Betting Odds: Philadelphia Phillies -290 / Pittsburgh Pirates +235 — Over/Under: 8.5

(Get latest betting odds)

The Pittsburgh Pirates and Philadelphia Phillies meet Saturday in MLB action at Citizens Bank Park. Here’s a Pittsburgh Pirates vs Philadelphia Phillies Prediction. This article will include a Pittsburgh Pirates vs Philadelphia Phillies Pick.

Pittsburgh Pirates Betting Preview

The Pittsburgh Pirates are 15-30 on the year and play the Reds, Brewers, and Diamondbacks next. The Pittsburgh Pirates are batting .219 on the season, have a .230176 OBP, and a .326 slugging percentage. The Pittsburgh Pirates’ pitching staff has a 4.11 ERA and a 1.28 WHIP. Ke’Bryan Hayes leads the Pittsburgh Pirates with 40 hits and 15 RBI, while Bryan Reynolds and Joey Bart have combined for 67 hits and 30 RBI. 

Carmen Mlodzinski gets the ball for the Pittsburgh Pirates, and he is 1-3 with a 5.20 ERA and 26 strikeouts this season. Mlodzinski is 1-0 with a 1.93 ERA and 6 strikeouts in his career against the Philadelphia Phillies.

Philadelphia Phillies Betting Preview

The Philadelphia Phillies are 26-18 on the year and play the Rockies, Athletics, and Braves next. The Philadelphia Phillies are batting .258 on the season, have a .337 OBP, and a .401 slugging percentage. The Philadelphia Phillies pitching staff has a 3.90 ERA and a 1.26 WHIP. Trea Turner leads the Philadelphia Phillies with 52 hits and 15 RBI, while Nick Castellanos and Kyle Schwarber have combined for 89 hits and 59 RBI.

Zack Wheeler gets the ball for the Philadelphia Phillies, and he is 4-1 with a 2.95 ERA and 74 strikeouts this season. Wheeler is 4-1 with a 2.68 ERA and 60 strikeouts in his career against the Pittsburgh Pirates.

Why the Philadelphia Phillies will win

  • The Phillies have won each of their last 10 Saturday night home games.
  • The Pirates have lost each of their last nine Saturday road games against National League opponents.
  • The Phillies have covered the run line in 12 of their last 13 Saturday night games as home favorites against National League opponents.
  • The Pirates have failed to cover the run line in nine of their last 10 Saturday games against National League opponents.

Why the Pittsburgh Pirates will win

  • The Phillies have lost four of their last five games as home favorites against National League opponents following a win.
  • The Pirates have won each of their last three games as road underdogs against the Phillies following a road loss.
  • The Phillies have failed to cover the run line in each of their last seven games against the Pirates following a home win.
  • The Pirates have covered the run line in each of their last seven games against NL East opponents following a loss.

Philadelphia Phillies Player Prop Facts

  • Nick Castellanos has recorded a Double in three of the Phillies’ last four games against the Pirates.
  • Kyle Schwarber has hit a home run in seven of his last 12 home appearances against opponents that held a losing record.
  • J.T. Realmuto has recorded at least one RBI in each of his last five appearances against NL Central opponents at Citizens Bank Park.
  • Zack Wheeler has recorded eight or more strikeouts in four of his last five appearances.
  • Trea Turner has scored at least one run in each of the Phillies’ last seven games at Citizens Bank Park against opponents that held a losing record.
  • Zack Wheeler has recorded a win in eight of his last 10 appearances at Citizens Bank Park against opponents that held a losing record.
  • Trea Turner has recorded at least one Single in each of his last seven appearances in night games against NL Central teams that held a losing record.
  • Alec Bohm has recorded at least one hit in each of his last 14 appearances at Citizens Bank Park against opponents that held a losing record.
  • Zack Wheeler ranks 2nd in the league for total Strikeouts (74) this season.

Pittsburgh Pirates Player Prop Facts

  • Andrew McCutchen has hit a home run in three of his last six appearances at Citizens Bank Park against NL East opponents that held a winning record.
  • Jared Triolo has scored at least one run in each of his last four appearances against the Phillies after playing the previous day.
  • Jared Triolo has recorded two hits in each of his last four appearances against the Phillies after playing the previous day.
  • Ke’Bryan Hayes has recorded at least one Single in nine of his last 10 appearances after playing the previous day.
  • Jack Suwinski has recorded at least one RBI in three of his last four appearances at Citizens Bank Park against NL opponents that held a winning record.

Pittsburgh Pirates vs Philadelphia Phillies Prediction

The Pirates continue to rack up the losses and have won just four games since April 26. It’s hard to back the Pirates with confidence, and it’s even tougher with Mlodzinski on the mound given his 5.20 ERA and 1.54 WHIP. In 17.2 road innings, Mlodzinski has a 6.62 ERA and a .288 allowed batting average. The Phillies are playing consistent ball, and you should like their chances with Wheeler on the mound. Wheeler has a 2.95 ERA and 0.91 WHIP on the season. In 20.2 home innings, Wheeler has a 2.18 ERA and .176 allowed batting average. In 77 at-bats against the current Pirates, Wheeler is allowing a .195 batting average, .271 on-base percentage, and has 28 strikeouts. The line is what it is for a reason, folks. Give me the Phillies and the RL for max betting value. 

Randy Chambers's Pick: Philadelphia Phillies -1.5

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