Jun 16, 2025; West Sacramento, California, USA; Houston Astros outfielder Jose Altuve (27) hits a home run against the Athletics during the first inning at Sutter Health Park. Mandatory Credit: Ed Szczepanski-Imagn Images

Oakland Athletics vs Houston Astros Prediction 06/17/2025 Picks

Pick details

Houston (41-31) vs Oakland (30-44)

June 17, 2025 at 10:05 PM EDT

The Line: Betting Odds: Oakland +120 / Houston -140 — Over/Under: 10.5

(Get latest betting odds)

The Houston Astros are visiting the Athletics on Tuesday, June 17th at the Sutter Health Park in the second game of this series, with the Athletics having the 1-0 lead. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Houston Astros vs Athletics Prediction. We will examine:
The Athletics recent form and player performance
The Houston Astros recent form and player performance
Recent betting trends and streaks involving the Athletics
Recent betting trends and streaks involving the Houston Astros
Recent betting trends in games played between the Houston Astros vs Athletics
A summary that ties it all together and produces a favorable betting outcome for the Houston Astros vs Athletics game

Athletics Preview

The Athletics have a 30-44 record this season and are sitting on the last place of the AL West. The Athleticshave a 13-23 home record and are 40-29 in over/under They are coming off a 3-1 home victory over the Astros, and have four consecutive wins. Under is 3-0 in their last 3 games and are playing the Guardians and the Tigers next.

The Athletics have a .253 batting average this season, .320 OBP and .418 Slugging percentage. Athletics’ pitching staff has a 5.42 ERA and 1.49 WHIP. Jacob Wilson leads the Athletics with 98 hits and a team-high .362 batting average, while Tyler Soderstrom leads the team with 45 RBI, and Brent Rooker adds a team-high 15 home runs.

JP Sears (L) is the projected starter for the Athletics, and he has a 5-5 record, 5.08 ERA and 1.25 WHIP. He has been weaker at home, with a 6.00 ERA in his 5 home starts, and he has been in terrible form lately, with a 1-4 record in his last 5 games and an 8.75 ERA in that span. In his previous start against the Astros this season, he got torched for 9 earned runs in 3.1 innings pitched. JP Sears is 2-3 with an ERA of 5.36 and 20 strikeouts in 9 appearances versus the Astros in his career.

Houston Astros Preview

The Houston Astros have a 41-31 record this season and are sitting on the first place of the AL West. The Astroshave a 14-18 road record and 28-41 in over/under. They are coming off a 1-3 road defeat by the Athletics, which snapped their previous five-game winning streak. Under is 6-2 in their last 8 games, and they are playing the Angels and the Phillies next.

The Astros have a .253 batting average this season, .317 OBP and .391 slugging percentage. Houston’s pitching staff has a 3.43 ERA and 1.15 WHIP. Jeremy Pena leads the Astros with 89 hits and he is the team’s best hitter, with a .320 batting average. Isaac Paredes leads the team in RBI with 42, adding a team-high 15 home runs.

Reliever Jason Alexander (R) is the projected starter for the Astros, and he has a 0-0 record, 18.00 ERA and 2.83 WHIP. He is coming off a terrible game, where he gave up 9 runs in just 2.1 innings pitched, and he has never faced the Astros before in his career.

Why the Athletics will win

The Athletics have won each of their last four games as underdogs.
The Astros have lost seven of their last 12 games as road favorites against American League opponents.
The Athletics have covered the run line in each of their last six games.
The Astros have failed to cover the run line in four of their last five games as favorites.
The Athletics have led after 3 innings in four of their last five home games.

Why the Houston Astros will win

The Astros have won each of their last eight games against AL West opponents following a loss.
The Athletics have lost 11 of their last 12 games against AL West opponents.
The Astros have covered the run line in each of their last six night games against AL West opponents following a road loss.
The Athletics have failed to cover the run line in six of their last seven night games against American League opponents that held a winning record.
The Astros have led after 3 innings in each of their last four night games against American League opponents.
The Astros have won the first inning in three of their last four night games against American League opponents.
The Astros have led after 5 innings in seven of their last nine games as road favorites against AL West opponents.

Total Runs Facts

Four of the Astros’ last five road games against AL West opponents have gone UNDER the total runs line.
Four of the Athletics’ last five games after playing the previous day have gone UNDER the total runs line.
The ‘Inning 1 OVER 0.5 runs’ market has hit in 10 of the Athletics’ last 11 games as home underdogs against AL West opponents.
The ‘Inning 1 UNDER 0.5 runs’ market has hit in six of the Astros’ last seven road games.

Matchup/League Facts

The Athletics rank 30th in the league for home runs allowed this season (105).
The Athletics rank 29th in the league for ERA this season (5.42).
The Astros rank 1st in the league for strikeouts this season (711).

Houston Astros vs Athletics Prediction

The Astros are 3-1 in their last 4 meetings against the A’s, but the A’s are 4-2 in their last 6 home meetings. Over is 5-2-1 in their last 8 meetings.  
In this Houston Astros vs Athletics Prediction, the Astros are coming as -140 road favorites. The Astros are rightfully favored, as they have a better overall record, but they have been below average on the road. the Astros are going with a bullpen game today, and the A’s put Sears on the mound, so I don’t trust either side in this spot. The A’s have the worst bullpen in the league, and Sears has been terrible at home with a 6.00 ERA. The Astros are also very good against lefties, averaging 5.1 runs per game against left-handed pitching, and in a hitter-friendly park, I expect a high-scoring game tonight. Take the over 10.5 runs.
 
 

Nikos Lagouretos's Pick: Over 10.5

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