Sep 14, 2025; Boston, Massachusetts, USA; New York Yankees shortstop Jose Caballero (72) high-fives first baseman Ben Rice (22) after hitting a home run against the Boston Red Sox during the seventh inning at Fenway Park. Mandatory Credit: Brian Fluharty-Imagn Images

New York Yankees vs Minnesota Twins Prediction 9/15/2025 Today’s MLB Picks

Pick details

New York (83-66) vs Minnesota (65-84)

September 15, 2025 at 07:40 PM EDT

The Line: Betting Odds: Minnesota +1.5 — Over/Under: +8.5

(Get latest betting odds)

The New York Yankees and Minnesota Twins meet Monday in MLB action at Target Field. Here’s a New York Yankees vs Minnesota Twins Prediction. This article will include a New York Yankees vs Minnesota Twins Pick.

New York Yankees Betting Preview


The New York Yankees are 83-66 on the year and play the Orioles, White Sox, and Orioles next. The New York Yankees are batting .249 on the season, have a .329 OBP, and a .454 slugging percentage. The New York Yankees pitching staff has a 4.00 ERA and a 1.27 WHIP. Aaron Judge leads the New York Yankees with 163 hits and 102 RBI, while Cody Bellinger and Paul Goldschmidt have combined for 275 hits and 136 RBI.

Carlos Rodon gets the ball for the New York Yankees, and he is 16-8 with a 3.11 ERA and 186 strikeouts this season. Rodon is 9-3 with a 4.00 ERA and 93 strikeouts in his career against the Minnesota Twins.

Minnesota Twins Betting Preview


The Minnesota Twins are 65-84 on the year and play the Guardians, Rangers, and Phillies next. The Minnesota Twins are batting .239 on the season, have a .313 OBP, and a .399 slugging percentage. The Minnesota Twins pitching staff has a 4.61 ERA and a 1.33 WHIP. Byron Buxton leads the Minnesota Twins with 119 hits and 76 RBI while Trevor Larnach and Brooks Lee have combined for 224 hits and 116 RBI.

Simeon Woods Richardson gets the ball for the Minnesota Twins, and he is 6-4 with a 4.58 ERA and 84 strikeouts this season. This will be Woods Richardson’s first career game against the New York Yankees.

New York Yankees @ Minnesota Twins Betting Trends: September 15, 2025


  • Probable Starting Pitcher: Simeon Woods-Richardson      Record this season: 6-4      ERA: 4.58
  • Home Record: 4-2
  • Last 5 against Yankees: –

Why the Minnesota Twins will win

  • The underdogs have won 10 of the Twins’ last 13 games.
  • The Yankees have lost each of their last four Monday games as road favorites.
  • The Twins have covered the run line in each of their last six games as underdogs against American League opponents.
  • The Yankees have failed to cover the run line in eight of their last 10 games as road favorites against American League opponents following a road loss.

  • Probable Starting Pitcher: Carlos Rodon      Record this season: 16-8      ERA: 3.11
  • Road Record: 7-4
  • Last 5 against Twins: 4-0

Why the New York Yankees will win

  • The Twins have lost each of their last six home games after playing the previous day.
  • The Yankees have won 10 of their last 11 games against teams that held a losing record.
  • The Twins have failed to cover the run line in each of their last seven games at Target Field.
  • The Yankees have covered the run line in 10 of their last 11 games against teams that held a losing record.
  • The Twins have trailed after 3 innings in seven of their last eight games against AL East opponents.
  • The Twins have trailed after 5 innings in each of their last five home games against AL East opponents.

Total Runs Facts

  • Ten of the Twins’ last 12 night games against American League opponents have gone OVER the total runs line.
  • Four of the Yankees’ last five night games against American League opponents have gone OVER the total runs line.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Yankees’ last four games against American League opponents.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in six of the Twins’ last seven home games against AL East opponents.

Minnesota Twins Player Prop Facts

  • Byron Buxton has hit at least one home run in three of his last four appearances against the Yankees at Target Field.
  • Trevor Larnach has recorded at least one hit in nine of his last 10 home appearances against AL opponents.

New York Yankees Player Prop Facts

  • Aaron Judge has hit at least one home run in four of the Yankees’ last five games as favorites against AL Central opponents.
  • Carlos Rodon has recorded a win in each of his last four appearances against the Twins.
  • Anthony Volpe has recorded at least one hit in each of the Yankees’ last 12 games as favorites against the Twins.
  • Aaron Judge has recorded two or more Doubles in three of the Yankees’ last four games at Target Field.
  • Aaron Judge ranks 1st amongst qualified players for Batting Average (.326) this season.

Matchup/League Facts

  • The Twins rank 25th in the league for runs scored this season (632).
  • The Twins rank 25th in the league for RBIs this season (600).
  • The Yankees rank 1st in the league for RBIs this season (747).
  • The Yankees rank 1st in the league for slugging percentage this season (.454).

New York Yankees vs Minnesota Twins Prediction

Rodon has been rolling this season with a 3.11 ERA and 1.07 WHIP, and he’s allowed 15 hits and 4 earned runs in his last 18 innings. The Twins continue to play underachieving ball and Woods Richardson doesn’t provide much hope, as he’s allowed 12 hits and 10 earned runs in his last 13.2 innings. I have little confidence in the Twins in this spot, especially against a Yankees ace. Give me the Yankees.

Randy Chambers's Pick: New York Yankees

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