May 17, 2026; Chicago, Illinois, USA; Chicago Cubs right fielder Michael Conforto (20) runs the bases after hitting a three-run home run against the Chicago White Sox during the ninth inning at Rate Field. Mandatory Credit: David Banks-Imagn Images
David Banks-Imagn Images

Milwaukee Brewers vs Chicago Cubs Prediction 5/18/2026 Today’s MLB Picks

Pick details

MATCHUP Milwaukee Brewers Chicago Cubs
Team Records 26-18 29-18
Spread +1.5 -136 -1.5 113
Moneyline +135 -163
Total Over 10.5 (-108) Under 10.5 (-111)
Where Wrigley Field, Chicago, Illinois
When Monday, May 18, 2026
Time 07:40 PM EDT
TV MLB.TV

The Milwaukee Brewers and Chicago Cubs meet Monday in MLB action at Wrigley Field. Here’s a Milwaukee Brewers vs. Chicago Cubs Prediction. This article will include a Milwaukee Brewers vs. Chicago Cubs Pick.

Milwaukee Brewers Betting Preview

The Milwaukee Brewers are 26-18 on the year and play the Cardinals and Dodgers next. The Milwaukee Brewers are batting. 244 on the season, have a .333 OBP, and have a .360 slugging percentage. The Milwaukee Brewers’ pitching staff has a 3.26 ERA and a 1.22 WHIP. William Contreras leads the Milwaukee Brewers with 47 hits and 27 RBI, while Brice Turang and Jake Bauers have combined for 82 hits and 50 RBI.

Brandon Sproat gets the ball for the Milwaukee Brewers, and he is 1-2 with a 5.75 ERA and 36 strikeouts this season. This will be Sproat’s first career game against the Chicago Cubs.

Chicago Cubs Betting Preview

The Chicago Cubs are 29-18 on the year and play the Pirates and Astros next. The Chicago Cubs are batting .246 on the season and have a .343 OBP, and a .406 slugging percentage. The Chicago Cubs’ pitching staff has a 3.90 ERA and a 1.19 WHIP. Nico Hoerner leads the Chicago Cubs with 49 hits and 29 RBI, while Alex Bregman and Pete Crow-Armstrong have combined for 88 hits and 36 RBI.

Shota Imanaga gets the ball for the Chicago Cubs, and he is 4-3 with a 2.32 ERA and 59 strikeouts this season. Imanaga is 1-3 with a 5.73 ERA and 18 strikeouts in his career against the Milwaukee Brewers.

Why the Chicago Cubs will win

  • The Cubs have won each of their last 15 games at Wrigley Field.
  • The Brewers have lost 11 of their last 12 night games against National League opponents following a loss.
  • The Brewers have failed to cover the run line in 12 of their last 13 night games against National League opponents following a loss.
  • The Cubs have covered the run line in three of their last four games after going to extra innings.
  • The Cubs have led after 3 innings in seven of their last nine home games.
  • The Brewers have trailed after 5 innings in five of their last six games at Wrigley Field.

Why the Milwaukee Brewers will win

  • The Brewers have won each of their last six games as road underdogs against the Cubs following a loss.
  • The Cubs have lost four of their last five games as favorites after playing the previous day.
  • The Brewers have covered the run line in each of their last 15 games as road underdogs against NL Central opponents following a loss.
  • The Cubs have failed to cover the run line in each of their last seven games as home favorites against NL Central opponents following a road loss.

Total Runs Facts

  • Each of the Brewers’ last four games as underdogs has gone UNDER the total runs line.
  • Four of the Cubs’ last five games after going to extra innings have gone OVER the total runs line.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Cubs’ last four games against National League opponents.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in four of the Brewers’ last five games against NL Central opponents.

Chicago Cubs Player Prop Facts

  • Seiya Suzuki has hit a home run in each of the Cubs’ last three Monday games against NL opponents that held a winning record.
  • Shota Imanaga has recorded a win in each of his last three appearances at Wrigley Field.
  • Shota Imanaga has recorded six or more strikeouts in eight of his last nine appearances with the Cubs as home favorites against NL Central opponents.
  • Alex Bregman has recorded at least one hit in each of his last eight appearances.
  • Shota Imanaga ranks 10th amongst qualified players for Earned Run Average (2.32) this season.

Milwaukee Brewers Player Prop Facts

  • Andrew Vaughn has hit a home run in two of his last three appearances against NL Central opponents.
  • Sal Frelick has recorded a hit in each of the Brewers’ last nine games as road underdogs.

Matchup/League Facts

  • The Cubs rank T28th in the league for home runs allowed this season (64).
  • The Cubs rank 4th in the league for runs scored this season (241).
  • The Brewers rank 2nd in the league for hits allowed this season (323).
  • The Brewers rank 28th in the league for slugging percentage this season (.360).

Milwaukee Brewers vs Chicago Cubs Prediction

The Brewers have had success against Imanaga, so you can make a case for the road dog. The problem is we know what Imanaga is capable of when he’s right so I’ll trust the larger sample size. Sproat has been on the struggle bus through 36 innings with a 5.75 ERA and 1.53 WHIP. Also, the Cubs are 18-5 at home this season. Give me the Cubs and the reasonable price at home.

Randy Chambers's Pick: Chicago Cubs

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