Jun 14, 2025; Los Angeles, California, USA;  Los Angeles Dodgers designated hitter Shohei Ohtani reacts after a swinging strike during the sixth inning of a baseball game against the San Francisco Giants at Dodger Stadium. Mandatory Credit: Ryan Sun-Imagn Images

Los Angeles Dodgers vs San Diego Padres Prediction 06/16/2025 Picks

Pick details

San Diego (39-31) vs Los Angeles (43-29)

June 16, 2025 at 10:10 PM EDT

The Line: Betting Odds: Los Angeles -1.5 — Over/Under: +9

(Get latest betting odds)

In this article, we will formulate a Padres vs Dodgers prediction for this MLB game on Monday, June 16, at Dodger Stadium in Los Angeles, California. Let’s take a look at the prediction for this MLB matchup.

San Diego Padres Betting Preview

The San Diego Padres (39-31, 18-19 Away) snapped a three-game losing skid and avoided getting swept at the hands of the Arizona Diamondbacks with an 8-2 win in Game 3 of that series on Sunday. San Diego lost the last two series; alongside that one to the D-backs, they fell to the Los Angeles Dodgers. In Sunday’s 8-2 victory in Phoenix, Manny Machado and Jake Cronenworth led the offense with two RBI apiece, while Nick Pivetta got the win after allowing two runs on two hits with nine strikeouts and one walk across 7.0 innings of work.

This season, the Padres’ average 4.21 runs per game (17th in the MLB) on a .249/.316/.378 triple-slash. When it comes to pitching, the Padres’ staff has a 3.51 ERA (8th) and 1.21 WHIP (9th). Manny Machado leads the Padres with a .316 batting average, ten home runs, and 43 RBI this season.

Dylan Cease will take the mound for the Padres on Monday. The 29-year-old right-hander has a 2-5 record in 14 starts this year with a 4.28 ERA and 1.30 WHIP in 75.2 innings.

Los Angeles Dodgers Betting Preview

The Los Angeles Dodgers (43-29, 25-12 Home) responded to a series loss to the St. Louis Cardinals with wins over the Padres and Giants. Although they lost Game 1 to San Francisco, the Dodgers won the next two, clinching the series with a 5-4 win on Sunday. Andy Pages led the team with four RBI, while Dustin May got the win after allowing three runs on six hits with three strikeouts and four walks in 6.0 innings.

This year, the Dodgers average 5.54 runs per game (1st in the MLB) on a .264/.340/.459 triple-slash. When it comes to pitching, the Dodgers’ staff has a 4.19 ERA (22nd) and 1.31 WHIP (20th). Teoscar Hernandez leads the Dodgers with a .264 batting average, 13 home runs, and 50 RBI this season.

The projected starting pitcher for the Dodgers is Shohei Ohtani, who will get his first start since 2023.

Why the Los Angeles Dodgers will win

The Padres have lost seven of their last eight games at Dodger Stadium following a road win.
The Dodgers have won five of their last six games after playing the previous day.
The Padres have failed to cover the run line in four of their last five games at Dodger Stadium following a road win.

Total Runs Facts

Each of the Dodgers’ last four night games against National League opponents have gone OVER the total runs line.
Seven of the Padres’ last nine games as road underdogs have gone UNDER the total runs line.
The ‘Inning 1 OVER 0.5 runs’ market has hit in nine of the Dodgers’ last 10 home games.
The ‘Inning 1 UNDER 0.5 runs’ market has hit in eight of the Padres’ last nine games as road underdogs against National League opponents.

Matchup/League Facts

The Dodgers rank 1st in the league for home runs this season (112).
The Dodgers rank 1st in the league for RBIs this season (383).
The Padres rank 27th in the league for home runs this season (60).
The Padres rank 4th in the league for opponent batting average this season (.225).

Padres vs Dodgers Prediction

The Dodgers won seven of the previous ten H2H encounters, including four of the last five. This season, the Dodgers won two out of three H2Hs, and I am backing them to add another victory on Monday. Shohei Ohtani will pitch for the first time in the Dodgers uniform, but I am sure he didn’t forget how to do it, as he was quite effective on the mound earlier in his career with the Angels. Dylan Cease, on the other hand, was dominant in his previous start, which happened to be in an 11-1 win over the Dodgers, when he shut the opponents out in 7.0 innings. Prior to that, though, Cease surrendered three runs in four consecutive starts. There is no way he will register another shutout against the Dodgers here. Back the hosts to win.

Oliver Zivic's Pick: Dodgers ML

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