Sep 12, 2025; Seattle, Washington, USA; Seattle Mariners starting pitcher Luis Castillo (58) jokes with Los Angeles Angels designated hitter Mike Trout (27) during the sixth inning at T-Mobile Park. Mandatory Credit: Stephen Brashear-Imagn Images
Stephen Brashear-Imagn Images

Los Angeles Angels vs Seattle Mariners Prediction 9/26/2026 Today’s MLB Picks

Pick details

MATCHUP Los Angeles Angels Seattle Mariners
Team Records 62-98 74-86
Spread +1.5 -136 -1.5 113
Moneyline +161 -196
Total Over 7.5 (-115) Under 7.5 (-105)
Where T-Mobile Park, Seattle, Washington
When Saturday, September 26, 2026
Time 09:40 PM EDT
TV MLB.TV

The Los Angeles Angels and the Seattle Mariners will meet Saturday night in an American League West matchup at T-Mobile Park in Seattle, Washington. Let’s take a look at this matchup from a betting perspective.

Los Angeles Angels Betting Preview

The Los Angeles Angels enter Saturday’s contest with a 61-98 overall record (5th in the American League West) and a 34-47 mark on the road. The Angels offense has struggled this season. Los Angeles has compiled 648 runs scored (29th in MLB), 238 doubles, 153 home runs and .234 team batting average which ranks 29th in Major League Baseball.

The Angels arrive at this contest in good form. More specifically, Los Angeles has won the team’s last two games, including a 6-4 victory over the Seattle Mariners two days ago.

The Angels will turn to right hander Ryan Johnson in this game. In 18 starts made in 2026, Johnson has compiled a 5-9 win-loss record, a 4.93 ERA, a 1.35 WHIP and 76 strikeouts in 95 innings pitched. Ryan Johnson has pitched well recently, allowing one earned run or fewer in four of his last six starts made this season. Johnson will look to continue his recent success on the mound in tonight’s matchup with the Seattle Mariners.

Shifting our focus to the Los Angeles offense, the Angels lineup features Mike Trout and Zach Neto. Mike Trout has compiled a .246 batting average, 22 home runs, 54 RBIs, 26 doubles and an .813 OPS. Zach Neto has tallied a team leading 27 home runs, 77 RBIs, 31 doubles, 66 walks, 24 stolen bases and a .769 OPS.                                                                    

Seattle Mariners Betting Preview

The Seattle Mariners enter Saturday’s contest with a 74-86 overall record (3rd in the American League West) and a 41-38 mark at home. The Mariners arrive at this contest in below average form, losing three of the team’s last four games, including a 7-0 shutout loss to the Houston Astros earlier this week.

The Mariners will start left hander Kade Anderson in this contest. In six starts made this season, Anderson has compiled a 2-2 win-loss record, a 4.18 ERA, a 1.21 WHIP and 28 strikeouts in 32.1 innings pitched. Kade Anderson has pitched well recently, allowing one earned run or less in two of his last three starts made in 2026.  

The Seattle Mariners lineup features outfielder Randy Arozarena. Arozarena has compiled a .280 batting average, 26 home runs, 77 RBIs and an .862 OPS which ranks 16th in Major League Baseball.                          

Why the Los Angeles Angels will win.

• Starting pitching. In 18 starts made in 2026, Ryan Johnson has compiled a 5-9 win-loss record, a 4.93 ERA, a 1.35 WHIP and 76 strikeouts in 95 innings pitched.

• Recent form. The Los Angeles Angels arrive at this contest on the heels of a two-game winning streak.     

Why the Seattle Mariners will win.

• Home field advantage. The Seattle Mariners have amassed a 41-38 record at T-Mobile Park.

• Starting pitching. In six starts made this season, Kade Anderson has compiled a 4.18 ERA, a 1.21 WHIP and 28 strikeouts in 32.1 innings pitched.

Los Angeles Angels vs. Seattle Mariners Prediction

In my view, this matchup favors the Los Angeles Angels staying within the number (1.5) with the upside of winning the contest outright. Why? The Angels arrive at this contest in good form, winning the team’s last two games. Additionally, Los Angeles starting pitcher Ryan Johnson has pitched well recently, allowing one earned run or fewer in four of his last six starts made this season. With that said, I am backing the Los Angeles Angels plus the 1.5 runs in this game.

Hans Geevers's Pick: Los Angeles Angels +1.5

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