Los Angeles Angels vs Seattle Mariners Prediction 9/24/2026 Today’s MLB Picks

The Los Angeles Angels and the Seattle Mariners meet Thursday in MLB action from T-Mobile Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Los Angeles Angels vs. Seattle Mariners prediction.

Starting Pitching Matchup

The Los Angeles Angels send out Grayson Rodriguez will start here and Rodriguez is 4-8 with a 5.96 ERA and 83 strikeouts this season. Bryan Woo will start for the Seattle Mariners and is 12-9 with a 3.92 ERA and 167 strikeouts this season. 

Los Angeles Angels Recap

The Los Angeles Angels come into this game looking to rebound from their 7-3 loss at the hands of the Athletics last time out to sit at 60-98 this season. 

Angels Drop 3 Straight

Zach Neto leads the Angels across the board with a team-high 144 hits, 26 home runs, and 74 RBIs while adding 29 doubles and 5 triples so far this season. Mike Trout has added 124 hits with 26 doubles, 22 home runs, and 54 RBIs, while Nolan Schanuel has contributed 108 hits with 22 doubles, 7 home runs, and 49 RBIs on the year. Jo Adell has logged 101 hits with 16 doubles, a triple, 16 home runs, and 62 RBIs, while Vaughn Grissom has added 99 hits with 22 doubles, 13 home runs, and 70 RBIs. Oswald Peraza has recorded 76 hits with 12 doubles, 2 triples, 7 home runs, and 25 RBIs, and Jorge Soler has chipped in 64 hits with 16 doubles, a triple, 12 home runs, and 49 RBIs for Los Angeles up to this point in the season.

Seattle Mariners Recap

The Seattle Mariners come into this game looking to add on to their 6-5 win over the Houston Astros last time out to sit at 74-84 this season. 

Mariners Alternate Wins & Losses In 5 Straight

Josh Naylor and Randy Arozarena tie for the Mariners’ team lead with 155 hits each, with Naylor contributing 22 doubles, 10 home runs, and 55 RBIs while Arozarena paces Seattle across the board with a team-high 26 home runs and 76 RBIs along with 31 doubles and a triple so far this season. Julio Rodríguez has added 145 hits with 26 doubles, 21 home runs, and 68 RBIs, while Cole Young has logged 138 hits with 19 doubles, 4 triples, 17 home runs, and 65 RBIs on the year. Cal Raleigh has contributed 79 hits with 15 doubles, 23 home runs, and 68 RBIs, and Luke Raley has chipped in 59 hits with 9 doubles, a triple, 15 home runs, and 39 RBIs for Seattle up to this point in the season.

Los Angeles Angels @ Seattle Mariners Betting Trends: September 24, 2026

• Probable Starting Pitcher: Bryan Woo      Record this season: 12-9      ERA: 3.92
• Home Record: 8-1
• Last 5 against Angels: 2-0

Why the Seattle Mariners will win

• The Angels have lost each of their last 11 road games against the Mariners following a loss.
• The Mariners have won each of their last nine home games against the Angels.
• The Angels have failed to cover the run line in each of their last seven games.
• The Mariners have covered the run line in four of their last five home games against the Angels.
• The Angels have trailed after 3 innings in four of their last five games.
• The Angels have lost the first inning in three of their last four games at T-Mobile Park against opponents that held a losing record.
• The Angels have trailed after 5 innings in four of their last five games.

• Probable Starting Pitcher: Grayson Rodriguez      Record this season: 4-8      ERA: 5.96
• Road Record: 3-3
• Last 5 against Mariners: 1-0

Why the Los Angeles Angels will win

• The Mariners have lost seven of their last eight games as favorites against AL opponents following a win.
• The Angels have won each of their last four games as underdogs against AL West opponents following a loss.
• The Mariners have failed to cover the run line in each of their last 10 games as favorites against AL opponents following a win.
• The Angels have covered the run line in eight of their last nine games as road underdogs.
• The Mariners have trailed after 5 innings in five of their last six home night games.
• The Mariners have trailed after 3 innings in each of their last four home night games.

Total Runs Facts

• Each of the Mariners’ last five games after going to extra innings have gone OVER the total runs line.
• Each of the Angels’ last four road games have gone OVER the total runs line.
• There has been no run scored during the first inning in each of the Angels’ last four games as road underdogs against AL opponents.
• There has been at least one run scored in the first inning in five of Bryan Woo’s last six appearances as a starter.

Seattle Mariners Player Prop Facts

• J.P. Crawford has hit a home run in three of the Mariners’ last eight night games.
• Bryan Woo has recorded a win in nine of his last 10 home appearances against AL West opponents.
• Bryan Woo has recorded seven or more strikeouts in four of his last five home appearances against AL West opponents that held a losing record.
• Dominic Canzone has recorded at least one hit in each of the Mariners’ last 18 night games.
• Randy Arozarena ranks 10th amongst qualified players for On Base Percentage (.380) this season.

Los Angeles Angels Player Prop Facts

• Zach Neto has hit a home run in three of the Angels’ last four games as road underdogs against AL opponents.
• Grayson Rodriguez has recorded a win in each of his last four road appearances against AL West opponents.
• Zach Neto has recorded at least one hit in each of the Angels’ last 10 road games against AL West opponents.
• Grayson Rodriguez has recorded five or more strikeouts in each of his last 11 appearances against AL West opponents.
• Mike Trout ranks 7th amongst qualified players for On Base Percentage (.385) this season.

Matchup/League Facts

• The Mariners rank 30th in the league for doubles this season (199).
• The Mariners rank 29th in the league for hits this season (1215).
• The Angels rank 30th in the league for runs scored this season (635).
• The Angels rank 30th in the league for slugging percentage this season (.369).

Los Angeles Angels vs. Seattle Mariners Prediction

I’m on the Mariners here. I just think that Bryan Woo is the far better starting option in this game and while the Angels are getting a pretty price tag here, I think it’s for good reason as Grayson Rodriguez has been brutal up to this point in the year and Woo has been at his best for the most part at home so far this season. Give me the Mariners.

Chris Ruffolo's Pick: Seattle -195