Los Angeles Angels vs Seattle Mariners Prediction 9/14/2025 Today’s MLB Picks

The Los Angeles Angels and the Seattle Mariners meet Sunday in MLB action from T-Mobile Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Los Angeles Angels vs. Seattle Mariners prediction.

Starting Pitching Matchup

The Los Angeles Angels will start Kyle Hendricks here and Hendricks is 7-9 with a 4.58 ERA and 95 strikeouts this season. In his career, Hendricks is 2-0 with a 3.00 ERA and 12 strikeouts against Seattle. George Kirby will get the start for the Mariners here and is 8-7 with a 4.56 ERA and 106 strikeouts this season. In his last five starts against the Angels, Kirby is 4-1 with a 3.13 ERA and 37 strikeouts.

Los Angeles Angels Recap

The Los Angeles Angels come into this game looking to rebound from their 5-3 loss at the hands of the Mariners in Saturday’s matchup to drop to 69-80 this season. After this series, the Angels will go on the road once again for a series against the Milwaukee Brewers.

Angels Lose Three Straight

Logan O’Hoppe has 85 hits including 19 home runs and 43 RBIs while Nolan Schanuel has 123 hits with 22 doubles, a triple, 10 home runs and 49 RBIs. Luis Rengifo has 15 doubles with his 115 hits and Taylor Ward also has 120 hits as well while Mike Trout’s added 21 home runs and 58 RBIs so far this season. Jo Adell has 35 home runs and 94 RBIs. Ward has also chipped in 31 doubles, 30 home runs and 97 RBIs but has a team-high 158 strikeouts while Zach Neto has 29 doubles, 26 home runs, 62 RBIs and 26 stolen bases.

Seattle Mariners Recap

The Seattle Mariners come into this game looking to add on to their win over the Angels from Saturday’s matchup to sit at 81-68 this season. After this series, the Mariners will head on the road for a game against the Kansas City Royals.

Mariners Pick Up 8th Straight W

Jorge Polanco has 112 hits including 24 home runs and 70 RBIs while Cal Raleigh has 131 hits with 21 doubles, a team-high 53 home runs and 113 RBIs. Randy Arozarena has 136 hits with 30 doubles, 27 home runs, 73 RBIs and 28 stolen bases. Julio Rodriguez also has 162 hits with 27 doubles, 4 triples, 30 home runs, 89 RBIs and 26 stolen bases. J.P Crawford has 138 hits with 21 doubles, 9 home runs and 50 RBIs.

Los Angeles Angels @ Seattle Mariners Betting Trends: September 14, 2025

• Probable Starting Pitcher: George Kirby      Record this season: 8-7      ERA: 4.56
• Home Record: 4-3
• Last 5 against Angels: 4-1

Why the Seattle Mariners will win

• The Mariners have won each of their last eight games.
• The Angels have lost each of their last eight road games against the Mariners following a loss.
• The Angels have failed to cover the run line in five of their last six road games against the Mariners following a loss.
• The Mariners have covered the run line in eight of their last 10 day games against AL West opponents following a home win.
• The Mariners have led after 5 innings in each of their last five home day games.
• The Mariners have led after 3 innings in each of their last five home day games.

• Probable Starting Pitcher: Kyle Hendricks      Record this season: 7-9      ERA: 4.58
• Road Record: 2-4
• Last 5 against Mariners: 2-0

Why the Los Angeles Angels will win

• The Mariners have lost each of their last five day games against AL West opponents following a win.
• The Angels have won four of their last six games as underdogs following a loss.
• The Mariners have failed to cover the run line in each of their last seven day games against AL West opponents following a win.
• The Angels have covered the run line in each of their last seven day games against American League opponents following a loss.
• The Angels have led after 5 innings in five of their last six day games against AL West opponents.

Total Runs Facts

• Five of the Mariners’ last six games against American League opponents have gone OVER the total runs line.
• Four of the Angels’ last five day games after playing the previous day have gone UNDER the total runs line.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in six of the Angels’ last seven road games against AL West opponents.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in six of the Mariners’ last seven day games against AL West opponents.

Seattle Mariners Player Prop Facts

• Jorge Polanco has recorded at least one Double in each of the Mariners’ last seven home games.
• Cal Raleigh has hit at least one home run in three of the Mariners’ last four day games against opponents that held a losing record.
• George Kirby has recorded a win in seven of his last eight appearances in day games against AL West teams that held a losing record.
• Victor Robles has recorded at least one hit in each of his last 13 appearances in day games.
• Cal Raleigh ranks 1st in the league in Home Runs (53) this season.

Los Angeles Angels Player Prop Facts

• Jo Adell has hit a home run in four of his last five road appearances after playing the previous day.
• Nolan Schanuel has recorded at least one hit in each of his last eight appearances with the Angels as road underdogs against AL West opponents.
• Jo Adell ranks 8th in the league in Home Runs (36) this season.

Matchup/League Facts

• The Mariners rank 29th in the league for doubles this season (208).
• The Mariners rank T29th in the league for triples this season (8).
• The Angels rank 30th in the league for doubles this season (202).
• The Angels rank 30th in the league for strikeouts against this season (1478).

Los Angeles Angels vs. Seattle Mariners Prediction

I’m backing the Mariners in this one. I just think that the Mariners keep finding ways to win and smell blood in the water now that they’ve caught up to the Astros at the top of the AL West. The Angels will have spots where they can provide value down the stretch, I just don’t think this is one of those. Give me Seattle here.