Jun 15, 2025; Baltimore, Maryland, USA; Los Angeles Angels pitcher Yusei Kikuchi (16) throws during the first inning against the Baltimore Orioles at Oriole Park at Camden Yards. Mandatory Credit: Daniel Kucin Jr.-Imagn Images

Los Angeles Angels vs Boston Red Sox Prediction 06/25/2025 Picks

Pick details

Boston (40-41) vs Los Angeles (39-40)

June 25, 2025 at 04:07 PM EDT

The Line: Betting Odds: Los Angeles -125 / Boston +105 — Over/Under: +9

(Get latest betting odds)

The Boston Red Sox are visiting the Los Angeles Angelson Wednesday, June 25th at the Angel Stadium in the third game of this series, with the Angels having the 2-0 lead. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Boston Red Sox vs Los Angeles Angels Prediction. We will examine:
The Los Angeles Angels recent form and player performance
The Boston Red Sox recent form and player performance
Recent betting trends and streaks involving the Los Angeles Angels
Recent betting trends and streaks involving the Boston Red Sox
Recent betting trends in games played between the Boston Red Sox vs Los Angeles Angels
A summary that ties it all together and produces a favorable betting outcome for the Boston Red Sox vs Los Angeles Angels game

Los Angeles Angels Preview

The Los Angeles Angels have a 39-40 record this season and are sitting on the third place of the AL West. The Angels have a 18-18 home record and 41-37 in over/under They are coming off a 3-2 home victory over the Red Sox, and are 6-3 in their last 9 games. Over is 3-1 in their last 4 games and are playing the Braves and the Nationals next.

The Angels have a .226 batting average this season, .291 OBP and .403 Slugging percentage. LA’s pitching staff has a 4.55 ERA and 1.45 WHIP. Nolan Schanuel leads the Angels with 77 hits and he is the team’s best hitter with a .278 batting average. Taylor Ward leads the team with 53 RBI and a team-high 19 home runs.

Yusei Kikuchi (L) is the projected starting pitcher for the Angels, and he has a 2-6 record, 3.01 ERA and 1.43 WHIP. He has been excellent at home, with a 1.31 ERA across seven home starts, but he has given 2+ runs in three of his last four starts. In his previous start against the Red Sox this season, he gave up 3 runs in 5 innings of work.  

Boston Red Sox Preview

The Boston Red Sox have a 40-41 record this season and are sitting on the 4th place of the AL East. The Red Sox have a 18-24 road record and are 37-43 in over/under. They are coming off a 2-3 road defeat by the Angels and have four straight losses. They are playing the Blue Jays and the Reds next.

The Red Sox have a .248 batting average this season, .322 OBP and .416 slugging percentage. Boston’s pitching staff has a 3.95 ERA and 1.32 WHIP.  Jarren Duran leads the Red Sox with 87 hits, while being the team’s best hitter, with a .257 batting average. Trevor Story leads the team in RBI, with 38.

Richard Fitts (R) is the projected starting pitcher for the Red Sox, and he has a 0-3 record, 4.71 ERA and 1.29 WHIP. He has been excellent on the road, with a 1.93 ERA across three road starts, but he was torched by the Angels in his last start, with 5 earned runs in just one inning of work.

Why the Los Angeles Angels will win

The Red Sox have lost each of their last four games.
The Angels have won each of their last six games as home favorites against American League opponents.
The home team has covered the run line in each of the Angels’ last six games.
The Red Sox have failed to cover the run line in 10 of their last 11 games at Angel Stadium of Anaheim against teams that held a losing record.
The Angels have won the first inning in three of their last four home games against AL East opponents that held a losing record.
The Red Sox have trailed after 5 innings in each of their last four day games against American League opponents that held a losing record.
The Red Sox have trailed after 3 innings in each of their last four games as underdogs.

Why the Boston Red Sox will win

The Angels have lost each of their last 10 day games against AL East opponents following a win.
The underdogs have won four of the last five games between the Red Sox and Angels.
The Angels have failed to cover the run line in each of their last nine games as favorites against AL East opponents following a win.
The Red Sox have covered the run line in each of their last six games as road underdogs against AL West opponents following a loss.
The Angels have trailed after 3 innings in each of their last four games as favorites against AL East opponents.
The Angels have lost the first inning in four of their last five day games against American League opponents that held a losing record.
The Angels have trailed after 5 innings in each of their last seven Wednesday day home games.

Total Runs Facts

Six of the Red Sox’s last seven day games against AL West opponents have gone UNDER the total runs line.
Six of the Angels’ last seven day games against AL East opponents have gone OVER the total runs line.
The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Angels’ last six day games against AL East opponents.
The ‘Inning 1 OVER 0.5 runs’ market has hit in six of the Red Sox’s last seven day games.

Matchup/League Facts

The Angels rank 30th in the league for on-base percentage this season (.291).
The Angels rank 30th in the league for walks allowed this season (307).
The Red Sox rank 1st in the league for doubles this season (149).
The Red Sox rank 28th in the league for strikeouts against this season (752).

Boston Red Sox vs Los Angeles Angels Prediction

The Angels are 4-1 in their last 5 overall meetings against the Red Sox, and are 3-1 in their last 4 meetings against the Red Sox in Los Angeles.
In this Boston Red SoxvsLos Angeles AngelsPrediction, the Angelsare coming as -125 home favorites. Both teams have almost identical overall records, and have exactly 18 home/away wins. Both pitchers have been shaky this season, with a combined 7.71 ERA, but both are due for some negative regression, as they have a combined 10.13 ERA. The Angels have the third-worst bullpen in the majors, and the Red Sox are crushing lefties, with 5.4 runs per game against left-handed pitching. Both teams score 9.8 runs per game versus the opposing starter throw hand, so I expect a high-scoring game in LA today. Take the over 9 runs.

Nikos Lagouretos's Pick: Over 9

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