Detroit Tigers vs Arizona Diamondbacks Prediction 3/31/2026 Today’s MLB Picks

The Detroit Tigers and the Arizona Diamondbacks meet Tuesday in MLB action from Chase Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Detroit Tigers vs. Arizona Diamondbacks prediction.

Starting Pitching Matchup

The Detroit Tigers will send out Casey Mize for the start here and Mize was 14-6 with a 3.87 ERA and 139 strikeouts last season. This will be Mize’s second career start against the Diamondbacks. Brandon Pfaadt will start this game for Arizona and was 13-9 wtih a 5.25 ERA and 147 strikeouts last season. This will be Pfaadt’s second career start against Detroit. 

Detroit Tigers Recap

The Detroit Tigers come into this game looking to shake off a 9-6 loss at the hands of Arizona in Monday’s series opener to slip to 2-2 on the year. After this series, the Tigers will head home for a set against the St. Louis Cardinals.

Tigers Drop Back-To-Back Games

Dillon Dingler has 4 hits with a home run, a double and a team-high 5 RBIs while Colt Keith’s added a team-high 6 hits with 3 doubles and 2 RBIs. Kevin McGonigle’s added 5 hits with a pair of doubles and 4 RBIs and Spencer Torkelson’s added 3 hits with a double and 3 RBIs as well this season. 

Arizona Diamondbacks Recap

The Arizona Diamondbacks come into this game looking to add on to their win over the Tigers from Monday’s opener to push their record to 1-3 on the year. After this series, Arizona will take on the Atlanta Braves at home.

Diamondbacks Finally Get First Win

Corbin Carroll leads the Diamondbacks with 4 hits including a triple, a home run and a team-high 5 RBIs while Alek Thomas has logged 3 doubles with 4 RBIs as well this season. Ketel Marte and Geraldo Perdomo each have 4 hits with a home run and 2 RBIs, with Perdomo logging a double as well this season. 

Detroit Tigers @ Arizona Diamondbacks Betting Trends: March 31, 2026

• Probable Starting Pitcher: Brandon Pfaadt      Record this season: –      ERA: –
• Home Record: –
• Last 5 against Tigers: 0-1

Why the Arizona Diamondbacks will win

• The home team has won each of the Diamondbacks’ last seven games.
• The Tigers have lost seven of their last eight night games against National League opponents.
• The Diamondbacks have covered the run line in each of their last six night games against American League opponents.
• The Tigers have failed to cover the run line in each of their last six night games against National League opponents following a loss.
• The Diamondbacks have led after 3 innings in each of their last five home games against American League opponents.
• The Tigers have trailed after 5 innings in each of their last seven night games against National League opponents.

• Probable Starting Pitcher: Casey Mize      Record this season: –      ERA: –
• Road Record: –
• Last 5 against Diamondbacks: 0-0

Why the Detroit Tigers will win

• The Diamondbacks have lost each of their last seven games after playing the previous day.
• The Tigers have won 12 of their last 14 games against NL West opponents.
• The Diamondbacks have failed to cover the run line in each of their last four home games against AL Central opponents following a win.
• The Tigers have covered the run line in eight of their last 10 night games against NL West opponents that held a losing record.
• The Diamondbacks have trailed after 3 innings in each of their last five Tuesday games.
• The Tigers have led after 5 innings in nine of their last 12 games against NL West opponents.

Total Runs Facts

• Each of the last six games between the Tigers and Diamondbacks at Chase Field have gone OVER the total runs line.
• Each of the Tigers’ last six night games after playing the previous day have gone UNDER the total runs line.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in seven of the Tigers’ last eight night games.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in six of the Diamondbacks’ last seven night games at Chase Field.

Arizona Diamondbacks Player Prop Facts

• Brandon Pfaadt has recorded five or more strikeouts in four of his last five home appearances against AL opponents.
• Ildemaro Vargas has hit a home run in each of his last two home appearances against the Tigers.
• Ildemaro Vargas has recorded at least one hit in each of his last 13 appearances in night games.

Detroit Tigers Player Prop Facts

• Casey Mize has recorded four or more strikeouts in 10 of his last 11 appearances against opponents that held a losing record.
• Gleyber Torres has recorded at least one hit in 13 of his 14 previous road appearances against NL West opponents that held a losing record.
• Jake Rogers has hit a home run in three of his last seven appearances against NL opponents that held a losing record.
• Colt Keith ranks T10th amongst qualified players for Batting Average (.429) this season.

Matchup/League Facts

• The Diamondbacks rank T3rd in the league for triples this season (1).
• The Diamondbacks rank 27th in the league for ERA this season (5.73).
• The Tigers rank T29th in the league for home runs this season (1).
• The Tigers rank T5th in the league for doubles this season (8).

Detroit Tigers vs. Arizona Diamondbacks Prediction

I’m on the Tigers here. I think that the first game of the series was a bit of an anomaly as Detroit’s bullpen has been a lot more solid than what they showed in that opener and I think this is a good bounce back spot here. Mize was a really reliable option in Detroit’s rotation last season, and Pfaadt had more than his fair share of issues at home. I’ll side with Detroit in this one.

Chris Ruffolo's Pick: Detroit -125