Cleveland Guardians vs New York Yankees Prediction 6/4/25 MLB Picks

The Cleveland Guardians and New York Yankees meet Wednesday in MLB action at Yankee Stadium. Here’s a Cleveland Guardians vs New York Yankees Prediction. This article will include a Cleveland Guardians vs New York Yankees Pick.

Cleveland Guardians Betting Preview

The Cleveland Guardians are 32-27 on the year and play the Astros, Reds, and Mariners next. The Cleveland Guardians are batting .234 on the season, have a .307 OBP, and a .378 slugging percentage. The Cleveland Guardians’ pitching staff has a 4.05 ERA and a 1.38 WHIP. Jose Ramirez leads the Cleveland Guardians with 71 hits and 29 RBI, while Steven Kwan and Carlos Santana have combined for 120 hits and 50 RBI. 

Luis Ortiz gets the ball for the Cleveland Guardians, and he is 2-6 with a 4.40 ERA and 64 strikeouts this season. Ortiz is 0-2 with a 5.79 ERA and 15 strikeouts in his career against the New York Yankees.

New York Yankees Betting Preview

The New York Yankees are 37-22 on the year and play the Red Sox, Royals, and Red Sox next. The New York Yankees are batting .258 on the season, have a .343 OBP, and a .467 slugging percentage. The New York Yankees’ pitching staff has a 3.58 ERA and a 1.18 WHIP. Aaron Judge leads the New York Yankees with 86 hits and 50 RBI, while Paul Goldschmidt and Anthony Volpe have combined for 123 hits and 62 RBI.

Clarke Schmidt gets the ball for the New York Yankees, and he is 2-2 with a 3.95 ERA and 42 strikeouts this season. Schmidt is 1-1 with a 5.12 ERA and 25 strikeouts in his career against the Cleveland Guardians.

Why the New York Yankees will win

• The Yankees have won each of their last 12 Wednesday games against AL Central opponents.
• The Guardians have lost seven of their last eight games at Yankee Stadium.
• The Guardians have failed to cover the run line in each of their last six Wednesday night road games against American League opponents.
• The favorites have covered the run line in four of the last five games between the Guardians and Yankees at Yankee Stadium.
• The Guardians have trailed after 3 innings in four of their last five night games.
• The Yankees have led after 5 innings in seven of their last eight games as favorites.

Why the Cleveland Guardians will win

• The Guardians have won five of their last seven games as road underdogs against American League opponents following a loss.
• The Yankees have failed to cover the run line in each of their last eight Wednesday night games as favorites against American League opponents.
• The Guardians have covered the run line in seven of their last eight games as underdogs against American League opponents.

New York Yankees Player Prop Facts

• Jazz Chisholm has scored at least one run in each of the Yankees’ last six games as favorites against AL Central opponents.
• DJ LeMahieu has recorded at least one Single in 12 of his last 13 home appearances against the Guardians.
• Cody Bellinger has recorded at least one hit in each of his last nine appearances against AL opponents that held a winning record.
• Giancarlo Stanton has hit a home run in four of his last five appearances with the Yankees as favorites against the Guardians.
• Giancarlo Stanton has recorded at least one RBI in seven of his last eight appearances against AL Central opponents.
• Aaron Judge ranks 1st amongst qualified players for Batting Average (.387) this season.

Cleveland Guardians Player Prop Facts

• Carlos Santana has recorded a Double in three of his last four appearances with the Guardians as underdogs against AL opponents.
• Jose Ramirez has hit a home run in two of the Guardians’ last three games.
• Nolan Jones has recorded at least one RBI in four of the Guardians’ last five games.
• Jose Ramirez has scored at least one run in nine of the Guardians’ last 10 games as underdogs.
• Steven Kwan has recorded at least one Single in 10 of the Guardians’ last 11 night games against AL opponents that held a winning record.
• Carlos Santana has recorded at least one hit in each of his last nine appearances with the Guardians as underdogs.
• Jose Ramirez ranks T6th in the league in Hits (71) this season.

Cleveland Guardians vs New York Yankees Prediction

The Guardians continue to be hit or miss, and while Ortiz has been OK at times this season, he has a 6.39 ERA and .280 allowed batting average in 31 road innings. Ortiz isn’t going to like the Little League park that is Yankee Stadium. The Yankees continue to pile up the wins, and Schmidt has been more consistent this season, which includes allowing 23 hits and 10 runs in his last 28.2 innings. In 22.2 home innings, Schmidt has a 3.18 ERA and a .195 allowed batting average. The Yankees are at home, the better team, and have the pitching edge. Give me the Yankees, and I’ll lay the RL to shave down the juice.

Randy Chambers's Pick: New York Yankees -1.5