Cleveland Guardians vs Minnesota Twins Prediction 7/7/2026 Today’s MLB Picks

The Cleveland Guardians and the Minnesota Twins meet Tuesday in MLB action from Target Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Cleveland Guardians vs. Minnesota Twins prediction.

Starting Pitching Matchup

The Cleveland Guardians will send out Joey Cantillo for the start here and Cantillo is 7-3 with a 3.86 ERA and 89 strikeouts this season. Taj Bradley will get the nod for Minnesota and is 7-3 with a 3.86 ERA and 102 strikeouts this season. 

Cleveland Guardians Recap

The Cleveland Guardians come into this game looking to bounce back from a 7-6 loss at the hands of the White Sox last time out to fall to 47-44 this season. After this series, the Guardians will head on the road for a series against the Miami Marlins.

Guardians Lose Back-To-Back Games

Chase DeLauter has 75 hits with 15 doubles, 8 home runs and 41 RBIs while Steven Kwan has 62 hits with 9 doubles, a home run and 14 RBIs and Jose Ramirez has 64 hits with 18 doubles, 10 home runs and 33 RBIs this season. Brayan Rocchio has also added 81 hits with 13 doubles, 6 home runs and 37 RBIs this season while Angel Martinez has 54 hits with 11 doubles, 11 homers and 33 RBIs and Rhys Hoskins has added 36 hits with 13 doubles, 7 home runs and 29 RBIs. Daniel Schneemann has 49 hits with 10 doubles, 6 home runs and 28 RBIs this season. 

Minnesota Twins Recap

The Minnesota Twins come into this one looking to add on to their 6-1 win over the Yankees last time out to improve to 44-47 this season. After this series, the Twins will take on the Los Angeles Angels in a series at home.

Twins Win Back-To-Back Games

Byron Buxton has 83 hits with 16 doubles, a triple, 25 home runs and 45 RBIs while Josh Bell’s added 79 hits with 18 doubles, 13 home runs and 60 RBIs. Luke Keaschall has 73 hits with 13 doubles, 4 homers and 26 RBIs. Brooks Lee has 14 home runs with 48 RBIs and Victor Caratini has 34 RBIs while Kody Clemens has 68 hits with 17 doubles, 2 triples, 16 home runs and 43 RBIs this season.

Cleveland Guardians @ Minnesota Twins Betting Trends: July 7, 2026

• Probable Starting Pitcher: Taj Bradley      Record this season: 7-3      ERA: 3.86
• Home Record: 1-1
• Last 5 against Guardians: 1-1

Why the Minnesota Twins will win

• The Twins have won each of their last four night games against AL Central opponents that held a winning record.
• The Guardians have lost three of their last four road games.
• The Guardians have failed to cover the run line in each of their last nine night games against the Twins following a home loss.
• The Twins have covered the run line each of their last nine Tuesday games against AL Central opponents that held a winning record.
• The Twins have won the first inning in four of their last five games.
• The Twins have led after 5 innings in six of their last seven night games at Target Field against AL Central opponents.
• The Twins have led after 3 innings in four of their last five games.

• Probable Starting Pitcher: Joey Cantillo      Record this season: 7-3      ERA: 3.86
• Road Record: 3-2
• Last 5 against Twins: 0-1

Why the Cleveland Guardians will win

• The Guardians have won eight of their last nine games as underdogs against the Twins.
• The Twins have lost seven of their last eight games as home favorites following a win.
• The Guardians have covered the run line in each of their last nine games as underdogs against the Twins.
• The Twins have failed to cover the run line in each of their last six home games against the Guardians following a road win.
• The Twins have lost the first inning in each of their last three games as favorites against AL Central opponents.
• The Guardians have led after 5 innings in each of their last six night games against opponents that held a losing record.
• The Guardians have led after 3 innings in each of their last four games as underdogs against AL Central opponents.

Total Runs Facts

• Seven of the Twins’ last eight night games against AL Central opponents have gone OVER the total runs line.
• Five of the Guardians’ last six games as underdogs against the Twins have gone UNDER the total runs line.
• There has been at least one run scored in the first inning in each of the Twins’ last 10 games as favorites.
• There has been no run scored during the first inning in each of the Guardians’ last six road games against AL Central opponents.

Minnesota Twins Player Prop Facts

• Kody Clemens has hit a home run in three of the Twins’ last four games.
• Taj Bradley has recorded seven or more strikeouts in three of his last four appearances.
• Kody Clemens has recorded at least one hit in each of his last 12 appearances with the Twins as favorites.
• Byron Buxton ranks 2nd amongst qualified players for Slugging Percentage (.575) this season.

Cleveland Guardians Player Prop Facts

• Joey Cantillo has recorded six or more strikeouts in each of his last three road appearances against opponents that held a losing record.
• Steven Kwan has recorded at least one hit in each of the Guardians’ last nine road games against the Twins.
• Austin Hedges has hit a home run in two of his last three appearances.
• Joey Cantillo has recorded a win in each of his last five appearances in night games against AL teams that held a losing record.

Matchup/League Facts

• The Twins rank 26th in the league for ERA this season (4.78).
• The Twins rank 26th in the league for runs allowed this season (465).
• The Guardians rank 30th in the league for slugging percentage this season (.368).
• The Guardians rank 28th in the league for hits this season (688).

Cleveland Guardians vs. Minnesota Twins Prediction

I’m on the Guardians here. Not my favorite game on the board because of the matchup on both sides, but I think that the Guardians have the better bullpen and I’m not ready to trust the Twins’ bats against a left-handed pitching in this situation. Cleveland also has a really solid track record in Cantillo’s starts as a team this season so I’ll back Cleveland in this one.

Chris Ruffolo's Pick: Cleveland -105