Cleveland Guardians vs Baltimore Orioles Prediction 9/9/2026 Today’s MLB Picks

In this article, we will formulate a Guardians vs Orioles Prediction for this MLB matchup on Wednesday, September 9th in the third game of this series. Let’s take a look at the prediction for this MLB matchup.

Baltimore Orioles Preview

The Baltimore Orioles have a 70-76 record this season and are sitting in the 5th place of the AL East. They have a 35-39 home record and are coming off a 5-9 home loss against the Guardians. They will face the Blue Jays and the Mets next.

The Baltimore Orioles have a .234 batting average this season, .316 OBP and .394 Slugging percentage. Baltimore’s pitching staff has a 4.14 ERA and 1.34 WHIP. Pete Alonso is the team’s best hitter with a .268 batting average, while leading the team in RBI with 97, adding a team-high 34 home runs.

Shane Baz (R) is the projected starting pitcher for the Orioles, and he has a 5-15 record, 3.91 ERA and 1.33 WHIP.

Cleveland Guardians Preview

The Cleveland Guardians have a 74-72 record this season and are sitting in the 2nd place of the AL Central. They have a 38-33 road record and are coming off a 9-5 road win against the Orioles. They will face the Twins and the White Sox next.

The Cleveland Guardians have a .237 batting average this season, .314 OBP and .372 Slugging percentage. Cleveland’s pitching staff has a 3.77 ERA and 1.26 WHIP. Chase DeLauter is the team’s best hitter with a .294 batting average. Brayan Rocchio leads the team in RBI with 62, while Angel Martinez adds a team-high 14 home runs.

Foster Griffin (L) is the projected starting pitcher for the Guardians, and he has a 15-4 record, 3.26 ERA and 1.14 WHIP.

Cleveland Guardians @ Baltimore Orioles Betting Trends: September 9, 2026

• Probable Starting Pitcher: Shane Baz      Record this season: 5-15      ERA: 3.91
• Home Record: 3-7
• Last 5 against Guardians: 0-2

Why the Baltimore Orioles will win

• The Guardians have lost nine of their last 10 games as road favorites against AL East opponents following a road win.
• The Orioles have won each of their last four games as underdogs against AL Central opponents following a loss.
• The Guardians have failed to cover the run line in each of their last 11 games as road favorites against AL East opponents following a road win.
• The Orioles have covered the run line in each of their last five games against AL Central opponents following a loss.
• The Guardians have trailed after 5 innings in four of their last five games as road favorites against AL opponents.
• The Guardians have trailed after 3 innings in each of their last four games as favorites.
• The Guardians have lost the first inning in three of their last four games as favorites.

• Probable Starting Pitcher: Foster Griffin      Record this season: 15-4      ERA: 3.26
• Road Record: 8-2
• Last 5 against Orioles: 0-0

Why the Cleveland Guardians will win

• The Orioles have lost each of their last nine games as home underdogs following a loss.
• The Guardians have won seven of their last eight road games.
• The road team has covered the run line in seven of the Guardians’ last eight games.
• The Orioles have failed to cover the run line each of their last four night games against AL Central opponents that held a winning record.
• The Guardians have led after 5 innings in five of their last six night games against the Orioles.
• The Orioles have trailed after 3 innings in four of their last five games as underdogs against AL Central opponents.
• The Guardians have won the first inning in three of their last four games as favorites against the Orioles at Oriole Park at Camden Yards.

Total Runs Facts

• Eight of the Orioles’ last nine games against AL Central opponents have gone OVER the total runs line.
• Seven of the Guardians’ last eight games as road favorites have gone UNDER the total runs line.
• There has been no run scored during the first inning in seven of the Guardians’ last eight road games against AL East opponents.
• There has been no run scored during the first inning in six of Shane Baz’s last seven home appearances as a starter.

Baltimore Orioles Player Prop Facts

• Pete Alonso has hit a home run in three of the Orioles’ last four Wednesday night games at Oriole Park at Camden Yards.
• Shane Baz has recorded five or more strikeouts in eight of his last nine appearances against AL opponents that held a winning record.
• Pete Alonso has recorded at least one hit in each of the Orioles’ last 14 Wednesday games as underdogs.
• Pete Alonso ranks 9th in the league in Home Runs (34) this season.

Cleveland Guardians Player Prop Facts

• Foster Griffin has recorded a win in each of his last three road appearances against opponents that held a losing record.
• Jose Ramirez has recorded a hit in each of the Guardians’ last eight games as favorites against AL East opponents.
• Angel Martinez has hit a home run in three of the Guardians’ last four games as favorites against AL East opponents.
• Foster Griffin ranks T3rd in the league for Wins (15) this season.

Matchup/League Facts

• The Orioles rank 27th in the league for batting average this season (.234).
• The Orioles rank 27th in the league for strikeouts against this season (1351).
• The Guardians rank 29th in the league for home runs this season (136).
• The Guardians rank 29th in the league for slugging percentage this season (.372).

Guardians vs Orioles Prediction

The Guardians are 7-3 in their last 10 meetings against the Orioles and the over is 4-1 in their last 5 meetings.

In this Guardians vs Orioles Prediction, the Orioles are coming as -110 home favorites. I like the Guardians in this one with Foster Griffin on the mound, who has been excellent on the road with an 8-2 record and 3.14 ERA, while his previous start against the Orioles this season was a shutout. On the flip side, Baz had 4 earned runs in his previous start against the Guardians this season and the Orioles have both a weaker offense and bullpen recently and have been in terrible form, with a 1-7 record in their last 8 games. Take the Guardians to win this one on the road.

Nikos Lagouretos's Pick: Cleveland Guardians ML