Sep 1, 2025; Cincinnati, Ohio, USA; Toronto Blue Jays starting pitcher Chris Bassitt (40) pitches against the Cincinnati Reds in the first inning at Great American Ball Park. Mandatory Credit: Katie Stratman-Imagn Images
Katie Stratman-Imagn Images

Cincinnati Reds vs Toronto Blue Jays Prediction 9/26/2026 Today’s MLB Picks

Pick details

MATCHUP Cincinnati Reds Toronto Blue Jays
Team Records 74-86 77-82
Spread +1.5 -161 -1.5 133
Moneyline +136 -164
Total Over 8 (-105) Under 8 (-114)
Where Rogers Centre, Toronto, Ontario
When Saturday, September 26, 2026
Time 03:07 PM EDT
TV MLB.TV

The Cincinnati Reds and the Toronto Blue Jays will meet Saturday afternoon in an interleague matchup at Rogers Centre in Toronto, Ontario. Let’s take a look at this matchup from a betting perspective.

Cincinnati Reds Betting Preview

The Cincinnati Reds enter Saturday’s contest with a 74-86 overall record (5th in the National League Central) and a 36-43 mark on the road. The Reds offense has struggled to find consistency this season. Cincinnati has compiled 660 runs scored (26th in MLB), 216 doubles, 212 home runs and an abysmal .229 team batting average which ranks 30th in Major League Baseball.    

Cincinnati arrives at this contest in poor form. The Reds have lost four of the team’s last six games played this season, including the Atlanta Braves 3-2 victory over the Cincinnati Reds earlier this week.

The Reds will turn to right hander Rhett Lowder in this game. In 25 starts made in 2026, Lowder has compiled a 6-12 win-loss record, a 6.01 ERA, a 1.55 WHIP and 101 strikeouts in 127.1 innings pitched. Rhett Lowder arrives at this contest in poor form, allowing five earned runs or more in three of his last four starts made this season. Lowder will look to bounce back from his recent subpar performances on the mound in tomorrow afternoon’s matchup with the Toronto Blue Jays.

Turning our attention to the Cincinnati offense, the Reds lineup features shortstop Elly De La Cruz and first baseman Sal Stewart. Elly De La Cruz has tallied a .285 batting average (16th in MLB), 30 home runs, 77 RBIs and an .888 OPS which ranks 7th in Major League Baseball. Sal Stewart has amassed 32 home runs, 25 doubles, 63 walks, 110 RBIs and a .799 OPS.                                                                             

Toronto Blue Jays Betting Preview

The Toronto Blue Jays enter Saturday’s contest with a 78-82 overall record (5th in the American League East) and a 41-38 mark at home. The Blue Jays arrive at this contest in subpar form, losing five of the team’s last seven games played this season.

The Blue Jays will start right hander Spencer Miles in this contest. In eight starts made in 2026, Miles has compiled a 6-2 win-loss record, a 2.57 ERA, a 1.08 WHIP and 91 strikeouts in 94.2 innings pitched. Spencer Miles has pitched exceptionally well recently, allowing zero earned runs in September while striking out 14 batters across 11.1 innings pitched.

The Blue Jays lineup features Kazuma Okamoto and Ernie Clement. Kazuma Okamoto has tallied 33 home runs (11th in MLB), 89 RBIs, 56 walks, 24 doubles and a .759 OPS. Ernie Clement has amassed a .264 batting average and a .660 OPS.                             

Why the Cincinnati Reds will win.

• Starting pitching. In 25 starts made in 2026, Rhett Lowder has compiled a 6-12 win-loss record, a 6.01 ERA, a 1.55 WHIP and 101 strikeouts in 127.1 innings pitched.

• Motivation. The Reds have lost four of the team’s last six games.

Why the Toronto Blue Jays will win.

• Starting pitching. In eight starts made in 2026, Spencer Miles has compiled a 6-2 win-loss record, a 2.57 ERA, a 1.08 WHIP and 91 strikeouts in 94.2 innings pitched.

• Enhanced motivation. The Blue Jays have lost five of the team’s last seven games.

• Offensive balance. Ernie Clement and Kazuma Okamoto have been key contributors for the Toronto Blue Jays in 2026.

Cincinnati Reds vs. Toronto Blue Jays Prediction

In my view, this matchup favors the Toronto Blue Jays. Why? Toronto starting pitcher Miles has performed at a high level in 2026, compiling a 6-2 win-loss record, a 2.57 ERA, a 1.08 WHIP and 91 strikeouts in 94.2 innings pitched. Conversely, Cincinnati hurler Rhett Lowder arrives at this contest in poor form, allowing five earned runs or more in three of his last four starts made this season. With that said, the Blue Jays are the side to be on in this contest. I am backing the Toronto Blue Jays on the moneyline in this game.

Hans Geevers's Pick: Toronto Blue Jays ML

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