Cincinnati Reds shortstop Elly De La Cruz (44) sets for a pitch in the fourth inning of the MLB game between Cincinnati Reds and Minnesota Twins at Great American Ball Park in Cincinnati on Wednesday, June 18, 2025.

Cincinnati Reds vs Minnesota Twins Prediction 06/19/2025 Picks

Pick details

Minnesota (36-37) vs Cincinnati (39-35)

June 19, 2025 at 12:40 PM EDT

The Line: Betting Odds: Cincinnati -115 — Over/Under: 9

(Get latest betting odds)

The Minnesota Twins and the Cincinnati Reds meet Thursday in MLB action from Great American Ballpark. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Minnesota Twins vs. Cincinnati Reds prediction.

Starting Pitching Matchup

The Minnesota Twins will send out Chris Paddack for the start here and Paddack is 2-6 with a 4.30 ERA and 53 strikeouts this season. In his career, Paddack is 1-1 with a 4.09 ERA and 16 strikeouts against Cincinnati. Nick Martinez will get the start for the Reds here and is 4-7 with a 3.92 ERA and 58 strikeouts this season. In his last five starts against the Twins, Martinez is 1-1 with a 5.81 ERA and 22 strikeouts.

Minnesota Twins Recap

The Minnesota Twins come into this game looking to rebound from a 4-2 loss at the hands of the Reds in Wednesday’s matchup to sit at 36-37 on the year. After this series, the Twins will head home for an interleague series against the Minnesota Twins.

Twins Lose Sixth Straight

Byron Buxton has 58 hits along with 8 doubles, a team-high 13 home runs and 43 RBIs with 12 stolen bases and 3 triples while Carlos Correa has 54 hits with 13 doubles and Willi Castro has 52 hits with 11 doubles as well. Harrison Bader’s added 7 home runs and 27 RBIs while Buxton’s contributed a team-high 67 strikeouts as well this season. Ty France has also added 68 hits, 11 doubles, 5 home runs and 37 RBIs and Trevor Larnach’s chipped in 65 hits with 10 doubles, 10 home runs and 34 RBIs as well this season.

Why the Minnesota Twins will win

The Reds have lost nine of their last 12 games as home favorites against AL Central opponents following a win.
The underdogs have won eight of the Reds’ last 12 games.
The Reds have failed to cover the run line in nine of their last 10 home games against American League opponents that held a losing record.
The Twins have covered the run line in seven of their last eight games as underdogs against the Reds.

Minnesota Twins Player Prop Facts

Chris Paddack has recorded five or more strikeouts in each of his last five appearances against NL opponents.
Byron Buxton has recorded at least one RBI in each of his last four appearances with the Twins as road underdogs.
Willi Castro has recorded a Double in four of the Twins’ last five day games against NL opponents that held a winning record.
Willi Castro has recorded at least one hit in each of his last eight appearances in day games against NL teams that held a winning record.
Byron Buxton has scored at least one run in each of his last seven appearances with the Twins as road underdogs.
Byron Buxton has hit a home run in each of his last three road appearances with the Twins against NL opponents.

Cincinnati Reds Recap

The Cincinnati Reds come into this game looking to build on their win over Minnesota to sit at 39-35 on the year. After this series, the Reds will head on the road for a series against the St. Louis Cardinals.

Reds Win 4 Straight & 9 Of Last 11

Elly De La Cruz has 75 hits with 16 home runs, 50 RBIs, 14 doubles and 21 stolen bases while TJ Friedl has 77 hits with 12 doubles, 8 home runs and 28 RBIs with 9 stolen bases. Gavin Lux has added 59 hits with a team-high 14 doubles and 29 RBIs while Spencer Steer has 6 home runs and 24 RBIs and Matt McLain has added 8 homers, 26 RBIs and 11 stolen bases as well on the year. Jose Trevino’s also chipped in 15 doubles as well this season.

Why the Cincinnati Reds will win

The Twins have lost each of their last seven road games against teams that held a winning record.
The Reds have won each of their last six home games against American League opponents.
The Twins have failed to cover the run line in each of their last seven day games against National League opponents.
The Reds have covered the run line in each of their last five home games against American League opponents after playing the previous day.

Cincinnati Reds Player Prop Facts

Elly De La Cruz has hit a home run in each of the Reds’ last three day games.
Will Benson has recorded at least one RBI in each of the Reds’ last six home games against AL Central opponents.
Spencer Steer has recorded a Double in three of the Reds’ last four games against AL Central opponents that held a losing record.
Jose Trevino has recorded at least one hit in each of his last 10 appearances after playing the previous day.
Elly De La Cruz has scored at least one run in each of the Reds’ last six games against AL opponents that held a losing record.

Total Runs Facts

Seven of the Reds’ last eight home games against AL Central opponents have gone UNDER the total runs line.
Each of the Twins’ last three games after playing the previous day have gone UNDER the total runs line.

Minnesota Twins vs. Cincinnati Reds Prediction

I’m on the Reds here. The Twins just continue to be one of the streakier teams in baseball and It’s just hard to really feel good about the direction that this team is headed in right now and Chris Paddack isn’t the kind of pitcher to be a stopper for this team especially with how the Reds continue to smack right-handed pitching. I think the Reds get the W to pick up the big result from this series. Give me Cincinnati here.

Chris Ruffolo's Pick: Cincinnati -115

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