May 16, 2026; St. Louis, Missouri, USA; St. Louis Cardinals first baseman Alec Burleson (41) hits a one run single against the Kansas City Royals during the eighth inning at Busch Stadium. Mandatory Credit: Jeff Curry-Imagn Images
Jeff Curry-Imagn Images

Cardinals vs Cubs Prediction 8/14/2026 Today’s MLB Picks

Pick details

MATCHUP St. Louis Cardinals Chicago Cubs
Team Records 61-60 71-51
Spread +1.5 -149 -1.5 123
Moneyline +153 -186
Total Over 8 (-110) Under 8 (-110)
Where Wrigley Field, Chicago, Illinois
When Friday, August 14, 2026
Time 02:20 PM EDT
TV Apple TV

In this article we will formulate a Cardinals vs Cubs prediction for this MLB game on Friday, August 14th at Wrigley Field in Chicago, Illinois. Let’s take a look at the prediction for this MLB matchup. 

St. Louis Cardinals Betting Preview

The St. Louis Cardinals are 61-60 this season after they won two out of three against the Phillies by scores of 5-6, 2-0, and 7-1. In game three, St. Louis blew a 1-0 lead in the fourth inning, but they scored the last six runs to get the win. The Cardinals recorded eight hits in the game and they were led by Burleson, who went 2-3 with three RBIs. Leahy allowed six hits and one earned run over 5.0 innings for the win, while Graceffo threw 1.2 innings in relief. Prior to that series, St. Louis won two out of three against the Rockies and two out of three against the Yankees. 

This season, St. Louis has a 4.07 ERA with a 1.34 WHIP and a .253 opponent batting average, while they have scored 529 runs with a .241 batting average and a .316 on base percentage. Jordan Walker has led the Cardinals with 23 home runs and 84 RBIs, while Alec Burleson has added 19 home runs and 84 RBIs. The projected starting pitcher for St. Louis is Matthew Liberatore, who is 5-9 with a 5.15 ERA an da 1.52 WHIP over 113.2 innings pitched this season. 

Chicago Cubs Betting Preview

The Chicago Cubs are 71-51 this year after they won two out of three against the Nationals by scores of 8-6, 12-6, and 0-7. In game three, Chicago fell behind in the fourth inning and never woke up at the plate in the shutout loss. The Cubs recorded one hit and they were led by Busch, who went 1-3 in the game. Gausman allowed seven hits and six earned runs over 4.2 innings for the loss, while Civale thew 3.1 innings in relief. Prior to that series, Chicago won two out of three against the Royals and won a makeup game with the Blue Jays. 

This season, Chicago has a 4.10 ERA with a 1.26 WHIP and a .246 opponent batting average, while they have scored 634 runs with a .249 batting average and a .339 on base percentage. Pete Crow-Armstrong has led the Cubs with 27 home runs and 73 RBIs, while Dansby Swanson has added 18 home runs and 66 RBIs. The projected starting pitcher for Chicago is Clay Holmes, who is 4-5 with a 2.86 ERA and a 1.16 WHIP over 56.2 innings pitched this year. 

Why the Chicago Cubs will win

  • The Cubs have won each of their last six day games following a loss.
  • The Cardinals have lost seven of their last eight day games against National League opponents that held a winning record.
  • The Cubs have covered the run line in eight of their last nine games against NL Central opponents.
  • The Cardinals have failed to cover the run line in seven of their last eight day games against NL Central opponents following a home win.

Why the St. Louis Cardinals will win

  • The Cardinals have won five of their last six games as road underdogs against NL Central opponents following a win.
  • The Cubs have lost three of their last four games as home favorites against NL Central opponents following a loss.
  • The Cubs have failed to cover the run line in each of their last eight games at Wrigley Field following a road loss.
  • The underdogs have covered the run line in each of the Cubs’ last five games at Wrigley Field.
  • The Cubs have trailed after 3 innings in five of their last six home games against NL Central opponents.
  • The Cardinals have led after 5 innings in each of their last three day games.

Total Runs Facts

  • Seven of the Cardinals’ last eight games as road underdogs have gone UNDER the total runs line.
  • Four of the Cubs’ last five day games against NL Central opponents have gone OVER the total runs line.
  • There has been no run scored during the first inning in each of the Cardinals’ last five games as underdogs.
  • There has been at least one run scored in the first inning in five of the Cubs’ last six games as home favorites against National League opponents.

Chicago Cubs Player Prop Facts

  • Pete Crow-Armstrong has hit at least one home run in six of the Cubs’ last 10 games as home favorites against NL opponents.
  • Clay Holmes has recorded six or more strikeouts in four of his last five appearances.
  • Pete Crow-Armstrong has recorded at least one hit in each of the Cubs’ last 13 games as home favorites against NL opponents.

St. Louis Cardinals Player Prop Facts

  • Matthew Liberatore has recorded five or more strikeouts in four of his last five appearances with the Cardinals as underdogs.
  • Jordan Walker has recorded at least one hit in each of his last nine road appearances against opponents that held a winning record.
  • Everson Pereira has hit a home run in two of his last three appearances against opponents that held a winning record.

Cardinals vs Cubs Prediction 

Chicago comes into this matchup after a shutout loss, but they have won three of their last four games and they have scored 8+ runs in all three of those wins. The Cubs are 35-24 at home this year, while the Cardinals are 29-26 on the road. St. Louis has also won three of their last four games and they have scored 5+ runs in four of their last five. The Cardinals are starting Liberatore, who has allowed 5, 0, 3, and 5 earned runs in his last four starts, while Holmes has allowed four earned runs in back to back starts, but has only pitched once since May 15th. Take the over here.

David Racey's Pick: Over 8

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