Apr 26, 2026; Milwaukee, Wisconsin, USA; Milwaukee Brewers first baseman Jake Bauers (9) and second baseman Brice Turang (2) celebrates after beating the Pittsburgh Pirates at American Family Field. Mandatory Credit: Benny Sieu-Imagn Images
Benny Sieu-Imagn Images

Brewers vs Reds Prediction 9/4/2026 Today’s MLB Picks

Pick details

MATCHUP Milwaukee Brewers Cincinnati Reds
Team Records 87-54 67-73
Spread -1.5 -102 +1.5 -118
Moneyline -168 +139
Total Over 9.5 (-112) Under 9.5 (-108)
Where Great American Ball Park, Cincinnati, Ohio
When Friday, September 4, 2026
Time 06:10 PM EDT
TV MLB.TV

In this article we will formulate a Brewers vs Reds prediction for this MLB game on Friday, September 4th at Great American Ball Park in Cincinnati, Ohio. Let’s take a look at the prediction for this MLB matchup. 

Milwaukee Brewers Betting Preview

The Milwaukee Brewers are 87-54 this year after they split four games with the Cubs by scores of 3-17, 9-4, 9-5, and 1-2. In game four, Milwaukee cut the deficit to 2-1 in the fourth inning, but couldn’t find the tying run in the loss. The Brewers recorded five hits in the game and they were led by Vaughn, who went 1-4 with one home run and one RBI. Henderson allowed three hits and two earned runs over 7.0 innings for the loss, while Hall threw an inning in relief. Prior to that series, Milwaukee won two out of three against the Rangers and two out of three against the Mets. 

This season, Milwaukee has a 3.47 ERA with a 1.17 WHIP and a .221 opponent batting average, while they have scored 705 runs with a .256 batting average and a .339 on base percentage. Jake Bauers has led the Brewers with 23 home runs and 76 RBIs, while Brice Turang has added 17 home runs and 79 RBIs. The projected starting pitcher for Milwaukee is Shane Drohan, who is 7-5 with a 3.75 ERA and a 1.30 WHIP over 110.1 innings pitched this year. 

Cincinnati Reds Betting Preview

The Cincinnati Reds are 67-73 this season after they won two out of three against the Padres by scores of 0-5, 4-3, and 7-3. In game three, Cincinnati trailed 3-0 in the second inning, but they scored the last seven runs for the win. The Reds recorded 10 hits in the game and they were led by Brito, who went 1-3 with one home run and three RBIs. Williamson allowed seven hits and three earned runs over 5.1 innings for the win, while Antone picked up a hold. Prior to that series, Cincinnati won two out of three against the Cubs, but lost two out of three against the Giants before that. 

This season, Cincinnati has a 4.64 ERA with a 1.42 WHIP and a .252 opponent batting average, while they have scored 581 runs with a .228 batting average and a .307 on base percentage. Sal Stewart has led the Reds with 31 home runs and 105 RBIs, while Elly De La Cruz has added 21 home runs and 60 RBIs. The projected starting pitcher for Cincinnati is Rhett Lowder, who is 6-8 with a 5.14 ERA and a 1.46 WHIP over 112.0 innings pitched this season. 

Why the Cincinnati Reds will win

  • The Reds have won each of their last five Friday games as underdogs against NL Central opponents.
  • The Brewers have lost three of their last four games as favorites after playing the previous day.
  • The underdogs have covered the run line in 17 of the last 19 games between the Brewers and Reds at Great American Ball Park.
  • The Brewers have failed to cover the run line in eight of their last nine games as road favorites against the Reds following a loss.

Why the Milwaukee Brewers will win

  • The Reds have lost each of their last seven games against the Brewers at Great American Ball Park following a win.
  • The Brewers have won each of their last eight Friday games at Great American Ball Park.
  • The Reds have failed to cover the run line in each of their last seven night games at Great American Ball Park following a win.
  • The Brewers have covered the run line in each of their last four games following a road loss.
  • The Brewers have won the first inning in each of their last three night games against opponents that held a losing record.
  • The Brewers have led after 5 innings in four of their last five games against opponents that held a losing record.
  • The Brewers have led after 3 innings in four of their last five games against opponents that held a losing record.

Total Runs Facts

  • Each of the Reds’ last four games as underdogs against NL Central opponents have gone OVER the total runs line.
  • Five of the Brewers’ last six road games have gone OVER the total runs line.
  • There has been no run scored during the first inning in each of Shane Drohan’s last five road appearances as a starter.
  • There has been at least one run scored in the first inning in each of the Reds’ last four games against NL Central opponents.

Cincinnati Reds Player Prop Facts

  • Sal Stewart has hit a home run in four of the Reds’ last five games against NL Central opponents that held a winning record.
  • Rhett Lowder has recorded four or more strikeouts in seven of his last eight appearances with the Reds as underdogs against NL Central opponents.
  • Sal Stewart has recorded at least one hit in each of the Reds’ last 15 night games.

Milwaukee Brewers Player Prop Facts

  • Bo Naylor has hit a home run in two of his last three appearances with his team as a favorite against the Reds.
  • Luis Lara has recorded at least one hit in each of his last 14 appearances in night games.

Matchup/League Facts

  • The Reds rank 29th in the league for strikeouts against this season (1329).
  • The Reds rank 28th in the league for triples this season (12).
  • The Brewers rank T29th in the league for home runs this season (130).
  • The Brewers rank 2nd in the league for walks this season (578).

Brewers vs Reds Prediction 

Cincinnati comes into this matchup after winning three of their last four games and they have scored 5+ runs in three of their last five. The Reds are 34-37 at home this year, while the Brewers are 40-29 on the road. Milwaukee has lost three of their last five games, but they have scored nine runs in two of their last three. The Brewers are starting Drohan, who has allowed two earned runs or fewer in three straight outings, while Lowder has allowed 3+ earned runs in three straight starts. Take the Brewers -1.5 here.

David Racey's Pick: Brewers -1.5

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