Brewers vs Pirates Prediction 9/7/2025 Today’s MLB Picks

In this article we will formulate a Brewers vs Pirates prediction for this MLB game on Sunday, September 7th at PNC Park in Pittsburgh, Pennsylvania. Let’s take a look at the prediction for this MLB matchup. 

Milwaukee Brewers Betting Preview

The Milwaukee Brewers are 88-55 this season after they won the first two games in this series by scores of 5-2 and 4-1. In their game two win, Milwaukee scored the first four runs in the game and they picked up the easy victory. The Brewers recorded eight hits in the game and they were led by Bauers and Chourio, who both had two RBIs in the win. Milwaukee started Woodruff, who allowed two hits and zero earned runs over 6.0 innings for the win, while Ashby picked up the save. 

Prior to this series, the Brewers lost two out of three against the Phillies, but did win two out of three against the Blue Jays before that. Milwaukee has won three of their last four games and they continue to lead the NL Central. The Milwaukee pitching staff has a 3.60 ERA with a 1.23 WHIP and a .231 opponent batting average, while the offense has scored 726 runs with a .259 batting average and a .332 on base percentage this season. Christian Yelich has led Milwaukee with 27 home runs and 92 RBIs, while William Contreras has added 17 home runs and 69 RBIs this year. The projected starting pitcher for Milwaukee is Jacob Misiorowski, who is 4-2 with a 4.50 ERA and a 1.15 WHIP over 48.0 innings pitched this season. 

Pittsburgh Pirates Betting Preview

The Pittsburgh Pirates are 64-79 this year after they lost game two by a score of 4-1 on Saturday night. Pittsburgh didn’t do much at the plate in this game, but they did score in the ninth to avoid the shutout. The Pirates recorded five hits in the game and they were led by Cruz, who went 0-3 with one RBI in the loss. Pittsburgh started Keller, who allowed five hits and two earned runs over 6.1 innings for the loss, while Sisk allowed two earned runs in relief. 

Prior to this series, the Pirates won all three against the Dodgers and two out of three against the Red Sox. Pittsburgh has won three of their last five games and they are currently last in the NL Central standings. The Pittsburgh pitching staff has a 3.87 ERA with a 1.22 WHIP and a .237 opponent batting average, while their offense has scored 520 runs with a .234 batting average and a .307 on base percentage this season. Oneil Cruz has led Pittsburgh with 19 home runs and 56 RBIs, while Bryan Reynolds has added 15 home runs and 70 RBIs this year. The projected starting pitcher for Pittsburgh is Bubba Chandler, who is 2-0 with a 2.25 ERA and a 0.83 WHIP over 12.0 innings pitched this year. 

Why the Brewers will beat the Pirates 

The Brewers have won each of their last nine road games against National League opponents that held a losing record.
The Pirates have lost each of their last five games against the Brewers following a loss.
The Brewers have covered the run line each of their last nine road games against National League opponents that held a losing record.
The Pirates have failed to cover the run line in eight of their last nine games against the Brewers following a loss.

Total Runs Facts

Each of the Pirates’ last four games as underdogs against NL Central opponents have gone UNDER the total runs line.
Four of the Brewers’ last five games against NL Central opponents have gone UNDER the total runs line.
The ‘Inning 1 UNDER 0.5 runs’ market has hit in six of the Pirates’ last seven day games against National League opponents.
The ‘Inning 1 UNDER 0.5 runs’ market has hit in four of the Brewers’ last five day games against NL Central opponents.

Pittsburgh Pirates Player Prop Facts

Bryan Reynolds has recorded at least one hit in 11 of his last 12 appearances against the Brewers.
Oneil Cruz has hit a home run in five of his last 18 appearances with the Pirates as home underdogs against the Brewers.
Joey Bart has recorded a Double in three of his last four appearances in day games against teams that held a winning record.

Milwaukee Brewers Player Prop Facts

Christian Yelich has recorded at least one hit in each of his last 13 appearances with the Brewers as favorites against the Pirates.
Christian Yelich has hit a home run in two of his last three appearances with the Brewers as favorites against the Pirates.

Brewers vs Pirates Prediction

Pittsburgh came into this series playing their best ball of the season, but they have lost the first two and are trying to avoid being swept here. The Pirates are 42-32 at home this year, while the Brewers are 42-29 on the road. Milwaukee has scored at least five runs in three of their last five games and they are facing Chandler, who has allowed three earned runs and nine hits over 12.0 innings. The Pirates are going against Misiorowski, who has allowed three earned runs or more in four straight starts. I don’t love the pitching matchup for either side, but Milwaukee has the way better lineup. Take the Brewers -1.5 in this contest.