Jun 17, 2025; Toronto, Ontario, CAN;   Toronto Blue Jays shortstop Bo Bichette (11) hits a solo home run against the Arizona Diamondbacks in the ninth inning at Rogers Centre. Mandatory Credit: Dan Hamilton-Imagn Images

Boston Red Sox vs Toronto Blue Jays Prediction 06/27/2025 Picks

Pick details

Toronto (43-37) vs Boston (40-42)

June 27, 2025 at 07:10 PM EDT

The Line: Betting Odds: Boston -105 — Over/Under: +8.5

(Get latest betting odds)

The Toronto Blue Jays and the Boston Red Sox meet Friday in MLB action from Fenway Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Toronto Blue Jays vs. Boston Red Sox prediction.

Starting Pitching Matchup

The Toronto Blue Jays will send out Jose Berrios for the start here and Berrios is 3-3 with a 3.51 ERA and 81 strikeouts this season. In his last five starts against the Red Sox, Berrios is 4-0 with a 2.12 ERA and 30 strikeouts. Brayan Bello will get the start for the Red Sox here and is 3-2 with a 3.31 ERA and 51 strikeouts this season. In his last five starts against Toronto, Bello is 2-2 with a 4.78 ERA and 31 strikeouts.

Toronto Blue Jays Recap

The Toronto Blue Jays come into this game looking to add on to their 6-0 win over the Cleveland Guardians last time out to sit at 43-37 on the year. After this series, the Blue Jays will head home for a series against the New York Yankees.

Blue Jays Alternate Wins & Losses In 6 Straight

George Springer has 63 hits and Bo Bichette has 93 hits with Springer adding 11 home runs, a triple, 15 doubles and 38 RBIs while Bichette has 19 doubles, 11 home runs and 48 RBIs. Andres Gimenez has added 36 hits with 7 doubles and 4 home runs and 14 RBIs this season along with 9 stolen bases while Anthony Santander has 56 strikeouts so far this season. Vladimir Guerrero Jr. also has 11 homers, 16 doubles and 40 RBIs while Springer also has a .260 batting average and 62 strikeouts up to this point in the year. Addison Barger’s chipped in 16 doubles with 8 home runs and 24 RBIs and Ernie Clement’s added 17 doubles as part of his 77 hits this season.

Why the Toronto Blue Jays will win

The Red Sox have lost each of their last 10 games as home underdogs against the Blue Jays following a loss.
The Blue Jays have won each of their last nine games as road favorites against the Red Sox following a win.
The Blue Jays have covered the run line in seven of their last eight games against the Red Sox.
The Red Sox have failed to cover the run line in eight of their last nine home games against the Blue Jays following a loss.

Toronto Blue Jays Player Prop Facts

Ernie Clement has recorded a Double in three of the Blue Jays’ last four games as road favorites against AL opponents.
Jose Berrios has recorded a win in four of his last five appearances against the Red Sox.
Ernie Clement has recorded two or more hits in each of the Blue Jays’ last eight games as favorites against AL opponents.
Jose Berrios has recorded six or more strikeouts in five of his last six appearances against the Red Sox.
Daulton Varsho has hit a home run in each of the Blue Jays’ last two games against the Red Sox.
Bo Bichette ranks 5th in the league in Hits (93) this season.

Boston Red Sox Recap

The Boston Red Sox come into this game looking to rebound from their 5-2 loss at the hands of the Angels last time out to drop to 40-42 on the year. After this series, the Red Sox will take on the Cincinnati Reds at home.

Red Sox Lose Five In A Row

Alex Bregman has 59 hits including a team-high 17 doubles along with 11 home runs and 35 RBIs this season. Trevor Story’s added 70 hits with 11 home runs, 41 RBIs and 11 stolen bases while Jarren Duran has 87 hits with 20 doubles, 8 triples, 5 home runs, 38 RBIs and a team-high 15 stolen bases. Kristian Campbell’s added 51 hits with 10 doubles, 6 homers and 21 RBIs while Wilyer Abreu has 13 home runs with 36 RBIs and 4 stolen bases and Ceddanne Rafaela has 8 homers, 13 doubles, 2 triples, 30 RBIs and 11 stolen bases this season.

Why the Boston Red Sox will win

The Blue Jays have lost each of their last eight games as favorites against AL East opponents following a win.
The Red Sox have won each of their last four games as home underdogs against the Blue Jays.
The Blue Jays have failed to cover the run line in each of their last 11 games as favorites against AL East opponents following a win.
The Red Sox have covered the run line in 12 of their last 13 games as underdogs against AL East opponents following a road loss.

Boston Red Sox Player Prop Facts

Jarren Duran has hit a home run in each of his last three appearances against the Blue Jays after not playing the previous day.
Masataka Yoshida has recorded two or more hits in each of the Red Sox’s last four games as home underdogs against the Blue Jays.

Total Runs Facts

Each of the last seven games between the Blue Jays and Red Sox at Fenway Park have gone UNDER the total runs line.
Each of the Blue Jays’ last five games as road favorites have gone OVER the total runs line.

Toronto Blue Jays vs. Boston Red Sox Prediction

I’m backing the Blue Jays in this one. I get the case to be made for the Red Sox at home here but I’m not a Brayan Bello fan at Fenway as I have watched Bello implode at home far more often than not over the course of his career, and the Jays are just hitting well right now and not striking out a whole lot. The Red Sox are one of the worst in baseball against righties right now and Jose Berrios has solid numbers against the Red Sox in his career to begin with. Give me Toronto here.

Chris Ruffolo's Pick: Toronto -115

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