Boston Red Sox vs Minnesota Twins Prediction 4/15/2026 Today’s MLB Picks

The Boston Red Sox and the Minnesota Twins meet Wednesday in MLB action from Target Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Boston Red Sox vs. Minnesota Twins prediction.

Starting Pitching Matchup

The Boston Red Sox will start Connelly Early here and Early is 0-0 with a 2.63 ERA and 15 strikeouts this season. This will be Early’s first career start against the Twins. The Minnesota Twins will send out Simeon Woods Richardson here and Woods Richardson is 0-2 with a 4.60 ERA and 8 strikeouts this season. This will be Woods Richardson’s second career start against Boston.

Boston Red Sox Recap

The Boston Red Sox come into this game looking to shake off a 6-0 loss at the hands of the Twins on Tuesday to sit at 6-11 this season. After this series, the Red Sox will head home for a series against the Detroit Tigers. 

Red Sox Looking To Avoid Sweep

Wilyer Abreu leads the Red Sox with 22 hits including 4 doubles, a triple, 3 home runs and 10 RBIs while Trevor Story has 14 hits with 3 doubles, a homer and 12 RBIs and Marcelo Mayer’s added 8 hits with 3 doubles, a home run and 3 RBIs as well. Roman Anthony has 14 hits with 3 doubles, a triple, a home run and 3 RBIs so far this season while Jarren Duran has 10 hits with 3 doubles, a home run and 10 RBIs as well this season. Willson Contreras has added 17 hits with 2 doubles, 3 homers and 11 RBIs of his own on the year.

Minnesota Twins Recap

The Minnesota Twins come into this game looking to add on to their win over Boston last time out to sit at 11-7 this season. After this series, the Twins will take on the Cincinnati Reds in a series at home.

Twins Win 4 Straight

Luke Keaschall has 16 hits with 2 doubles, a home run and 9 RBIs while Josh Bell has 15 hits with 5 doubles and 3 home runs with 14 RBIs. Royce Lewis has 8 hits wtih 2 doubles, 2 home runs and 8 RBIs and Matt Wallner has 13 hits with 2 doubles. 3 home runs and 6 RBIs. Victor Caratini also has 13 hits and 8 RBIs this season. Byron Buxton has also chipped in 16 hits with 3 doubles, a triple, 3 home runs and 4 RBIs and Ryan Jeffers has 13 hits with 2 doubles, 2 home runs and 10 RBIs and Brooks Lee has added 12 hits with 3 home runs and 10 RBIs as well on the year.

Boston Red Sox @ Minnesota Twins Betting Trends: April 15, 2026

• Probable Starting Pitcher: Simeon Woods-Richardson      Record this season: 0-2      ERA: 4.60
• Home Record: 0-0
• Last 5 against Red Sox: 0-0

Why the Minnesota Twins will win

• The Twins have won seven of their last eight games as underdogs.
• The Red Sox have lost each of their last seven games against American League opponents.
• The Red Sox have failed to cover the run line in each of their last seven games as favorites against American League opponents.
• The Twins have covered the run line in each of their last six home games.
• The Twins have led after 3 innings in each of their last six games against AL East opponents.
• The Red Sox have trailed after 5 innings in each of their last eight games against American League opponents.
• The Red Sox have lost the first inning in seven of their last eight games as road favorites against American League opponents.

• Probable Starting Pitcher: Connelly Early      Record this season: 0-0      ERA: 2.63
• Road Record: 0-0
• Last 5 against Twins: –

Why the Boston Red Sox will win

• The Twins have lost six of their last seven games against AL East opponents following a home win.
• The Red Sox have won four of their last five day games against AL Central opponents.
• The Red Sox have covered the run line in each of their last six Wednesday games at Target Field.
• The Twins have failed to cover the run line in each of their last five Wednesday day home games.
• The Red Sox have led after 3 innings in each of their last four day games against the Twins.
• The Red Sox have led after 5 innings in four of their last five day games against the Twins.
• The Twins have lost the first inning in three of their last four day games against AL East opponents.

Total Runs Facts

• Six of the Red Sox’s last seven road games after playing the previous day have gone OVER the total runs line.
• Four of the Twins’ last five games have gone OVER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Red Sox’s last 11 games as road favorites against American League opponents.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Twins’ last five games.

Minnesota Twins Player Prop Facts

• Byron Buxton has hit at least one home run in four of his last five home appearances against the Red Sox.
• Byron Buxton has recorded at least one hit in each of his last 11 appearances against the Red Sox.

Boston Red Sox Player Prop Facts

• Jarren Duran has hit a home run in three of the Red Sox’s last four games against the Twins.
• Roman Anthony has recorded at least one hit in each of his last nine appearances in day games against AL teams that held a winning record.
• Willson Contreras ranks 6th amongst qualified players for On Base Percentage (.444) this season.

Matchup/League Facts

• The Twins rank 3rd in the league for home runs this season (24).
• The Twins rank 4th in the league for runs scored this season (98).
• The Red Sox rank 29th in the league for home runs this season (11).
• The Red Sox rank T28th in the league for steals this season (6).

Boston Red Sox vs. Minnesota Twins Prediction

I’m on the Twins here. I just think that Woods Richardson is a decent option for the Twins, it’s just that he hasn’t gotten the run support in much of his starts this season. Early is a solid arm for Boston, but the Twins have hit lefties well this season and are in solid form overall right now so I’ll back Minnesota here.

Chris Ruffolo's Pick: Minnesota +110