Jun 22, 2025; West Sacramento, California, USA; Cleveland Guardians catcher Austin Hedges (27) celebrates with pitcher Emmanuel Clase (48) after defeating the Athletics 3-0 at Sutter Health Park. Mandatory Credit: Dennis Lee-Imagn Images

Blue Jays vs Guardians Prediction 06/24/2025 Picks

Pick details

Toronto (41-36) vs Cleveland (39-37)

June 24, 2025 at 06:40 PM EDT

The Line: Betting Odds: Cleveland +1.5 — Over/Under: +8.5

(Get latest betting odds)

In this article we will formulate a Blue Jays vs Guardians prediction for this MLB game on Tuesday, June 24th at Progressive Field in Cleveland, Ohio. Let’s take a look at the prediction for this MLB matchup. 

Toronto Blue Jays Betting Preview
The Toronto Blue Jays are 41-36 this year after they lost two out of three against the White Sox by scores of 1-7, 7-1, and 2-4. In their game three loss, Toronto led 2-1 in the seventh inning, but they allowed the last three runs for the loss. The Blue Jays recorded eight hits and they committed one error in the game, while they were led by Bichette, who went 2-5 with two RBIs in the loss. Toronto started Bassitt, who allowed three hits and one earned run over 6.0 innings, while the Blue Jays also allowed three unearned runs in the loss. 

Prior to that series, the Blue Jays won two out of three against the Diamondbacks, but did lose all three against the Phillies before that. Toronto has lost six of their last nine games and they are currently third in the AL East standings. The Toronto pitching staff has a 4.17 ERA with a 1.24 WHIP and a .237 opponent batting average, while their offense has scored 330 runs with a .256 batting average and a .324 on base percentage this season. Bo Bichette has led Toronto with 11 home runs and 48 RBIs, while Vladimir Guerrero has added 10 home runs and 39 RBIs this year. The projected starting pitcher for Toronto is Eric Lauer, who is 3-1 with a 2.29 ERA and a 0.93 WHIP over 35.1 innings pitched this year. 

Cleveland Guardians Betting Preview
The Cleveland Guardians are 39-37 this season after they won two out of three against the Athletics by scores of 1-5, 4-2, and 3-0. In their game three win, Cleveland jumped out to a 2-0 lead in the second inning and they added one insurance run in the fifth to seal the win. The Guardians recorded eight hits and they committed one error in the game, while they were led by Arias, Jones, and Fry, who all had one RBI in the win. Cleveland started Cecconi, who allowed six hits and zero earned runs over 7.0 innings for the win, while Clase picked up the save. 

Prior to that series, the Guardians won two out of three against the Giants, but lost all three against the Mariners before that. Cleveland has won four of their last six games and they are currently second in the AL East standings. The Cleveland pitching staff has a 3.84 ERA with a 1.37 WHIP and a .251 opponent batting average, while the offense has scored 286 runs with a .230 batting average and a .300 on base percentage this season. Jose Ramirez has led Cleveland with 13 home runs and 36 RBIs, while Kyle Manzardo has added 11 home runs and 31 RBIs this year. The projected starting pitcher for Cleveland is Logan Allen, who is 5-4 with a 4.21 ERA and a 1.48 WHIP over 66.1 innings pitched this season. 

Why the Guardians will beat the Blue Jays
The Guardians have won eight of their last nine games at Progressive Field following a road win.
The Blue Jays have lost each of their last four games at Progressive Field against AL Central opponents that held a winning record.
The Guardians have covered the run line in eight of their last nine games at Progressive Field following a road win.
The Blue Jays have failed to cover the run line in five of their last six games at Progressive Field.
The Guardians have led after 3 innings in four of their last five games.
The Blue Jays have trailed after 5 innings in each of their last three games at Progressive Field against American League opponents that held a winning record.

Why the Blue Jays will beat the Guardians
The Guardians have lost four of their last five games as favorites against the Blue Jays following a road win.
The Blue Jays have won three of their last four games as underdogs against American League opponents.
The Guardians have failed to cover the run line in each of their last eight Tuesday games as home favorites against American League opponents.
The Blue Jays have covered the run line in seven of their last eight games as underdogs against AL Central opponents.
The Guardians have trailed after 3 innings in three of their last four home games against AL East opponents that held a winning record.
The Blue Jays have led after 5 innings in three of their last four road night games.

Total Runs Facts
Each of the Guardians’ last five games as favorites against American League opponents have gone UNDER the total runs line.
Eight of the Blue Jays’ last 10 games as underdogs have gone OVER the total runs line.
The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Guardians’ last six home games against American League opponents.
The ‘Inning 1 OVER 0.5 runs’ market has hit in six of the Blue Jays’ last seven night games.

Cleveland Guardians Player Prop Facts
Steven Kwan has hit a home run in each of the Guardians’ last two games against the Blue Jays at Progressive Field.
Steven Kwan has recorded at least one hit in each of his last 10 appearances at Progressive Field against AL opponents that held a winning record.
Carlos Santana has recorded at least one RBI in five of his last six appearances with his team as a favorite against the Blue Jays.
Steven Kwan has recorded a Double in three of his last four home appearances against AL opponents that held a winning record.
Carlos Santana has scored at least one run in each of his last five appearances against the Blue Jays at Progressive Field.

Toronto Blue Jays Player Prop Facts
Eric Lauer has recorded four or more strikeouts in 24 of his last 32 appearances in night games.
George Springer has recorded at least one hit in each of the Blue Jays’ last 10 games against AL opponents.
Anthony Santander has recorded at least one RBI in each of his last four appearances with his team as a road underdog against the Guardians.
Ernie Clement has recorded a Double in five of his last six appearances against former teams.
Vladimir Guerrero Jr. has scored at least one run in each of his last four road appearances against AL Central opponents that held a winning record.
Daulton Varsho has hit a home run in each of his last two road appearances after not playing the previous day.

Blue Jays vs Guardians Prediction 
Cleveland was able to end their road trip with two nice wins against the Athletics and they have allowed two runs or fewer in four of their last five games. The Guardians are 19-15 at home this year, while the Blue Jays are 16-20 on the road. Toronto has struggled over the last two weeks, but they are starting Lauer, who has allowed three earned runs in his last 9.1 innings pitched. Cleveland is going with Allen, who has allowed two earned runs in two straight starts. Take the under in this game, especially with this Cleveland offense scoring three runs or fewer in three of their last four. 

David Racey's Pick: Under 8.5

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