Baltimore Orioles vs St. Louis Cardinals Prediction 8/27/2026 Today’s MLB Picks

The Baltimore Orioles and St. Louis Cardinals meet Thursday in MLB action at Busch Stadium. Here’s a Baltimore Orioles vs St. Louis Cardinals Prediction. This article will include a Baltimore Orioles vs St. Louis Cardinals Pick.

Baltimore Orioles Betting Preview

The Baltimore Orioles are 65-68 on the year and play the Rockies and Athletics next. The Baltimore Orioles are batting .237 on the season, with a .319 OBP and a .399 slugging percentage. The Baltimore Orioles pitching staff has a 4.19 ERA and a 1.34 WHIP. Pete Alonso leads the Baltimore Orioles with 138 hits and 91 RBI, while Leody Taveras and Gunnar Henderson have combined for 199 hits and 100 RBI.

Trevor Rogers gets the ball for the Baltimore Orioles, and he is 9-8 with a 4.14 ERA and 114 strikeouts this season. Rogers is 0-2 with a 3.00 ERA and 15 strikeouts in his career against the St. Louis Cardinals.

St. Louis Cardinals Betting Preview

The St. Louis Cardinals are 66-68 on the year and play the Pirates and Dodgers next. The St. Louis Cardinals are batting .241 on the season, with a .316 OBP and a .382 slugging percentage. The St. Louis Cardinals’ pitching staff has a 4.24 ERA and a 1.34 WHIP. Alec Burleson leads the St. Louis Cardinals with 146 hits and 96 RBI, while Jordan Walker and JJ Wetherholt have combined for 265 hits and 144 RBI.

The St. Louis Cardinals didn’t list a starting pitcher at the time of this writing.

Why the St. Louis Cardinals will win

• The Cardinals have won each of their last four day games against teams that held a losing record.
• The Orioles have lost four of their last five day games against NL Central opponents.
• The Orioles have failed to cover the run line in each of their last four day games against NL Central opponents following a win.
• The Cardinals have covered the run line in six of their last seven day games against AL opponents following a loss.
• The Orioles have trailed after 5 innings in each of their last three day games against opponents that held a losing record.

Why the Baltimore Orioles will win

• The Cardinals have lost each of their last eight home games against AL East opponents following a home loss.
• The road team has won each of the last four games between the Orioles and Cardinals.
• The Cardinals have failed to cover the run line in eight of their last 10 games against AL East opponents following a home loss.
• The Orioles have covered the run line in seven of their last nine road games against NL opponents.
• The Cardinals have trailed after 5 innings in three of their last four home games against AL East opponents that held a losing record.
• The Cardinals have trailed after 3 innings in each of their last three home games against AL East opponents.

Total Runs Facts

• Each of the Cardinals’ last six games after playing the previous day have gone OVER the total runs line.
• Six of the Orioles’ last seven road games have gone OVER the total runs line.
• There has been no run scored during the first inning in each of Trevor Rogers’ last four road appearances as a starter.
• There has been at least one run scored in the first inning in five of the Cardinals’ last six games.

St. Louis Cardinals Player Prop Facts

• Nolan Gorman has hit a home run in two of his last three home appearances against the Orioles.
• Alec Burleson has recorded at least one hit in each of his eight previous appearances against the Orioles.

Baltimore Orioles Player Prop Facts

• Trevor Rogers has recorded a win in five of his last six road appearances against NL opponents.
• Pete Alonso has hit a home run in each of the Orioles’ last three road games.
• Trevor Rogers has recorded five or more strikeouts in six of his last seven road appearances against NL opponents.
• Pete Alonso has recorded at least one hit in each of his last eight appearances against the Cardinals.

Matchup/League Facts

• The Cardinals rank 5th in the league for strikeouts against this season (1047).
• The Cardinals rank 26th in the league for opponent batting average this season (.254).
• The Orioles rank 26th in the league for hits this season (1049).
• The Orioles rank 25th in the league for batting average this season (.237).

Baltimore Orioles vs St. Louis Cardinals Prediction

The Cardinals and the plus money are worth a look at home with the quick turnaround, but Rogers has looked like his old all-star self over the last two months. Rogers has allowed just 17 earned runs in his last 53.1 innings. The Orioles are 9-2 in Rogers’ last 11 starts. I don’t care who the Cardinals are throwing out there on the mound. The O’s have the edge behind this new and improved Rogers. Give me the Orioles and the soft price.

Randy Chambers's Pick: Baltimore Orioles