Houston Astros vs Cleveland Guardians Prediction 6/8/25 MLB Picks

The Houston Astros and Cleveland Guardians meet Sunday in MLB action at Progressive Field. Here’s a Houston Astros vs Cleveland Guardians Prediction. This article will include a Houston Astros vs Cleveland Guardians Pick.

Houston Astros Betting Preview

The Houston Astros are 36-28 on the year and play the White Sox, Twins, and Athletics next. The Houston Astros are batting .251 on the season, have a .317 OBP, and a .389 slugging percentage. The Houston Astros’ pitching staff has a 3.52 ERA and a 1.16 WHIP. Jeremy Pena leads the Houston Astros with 79 hits and 32 RBI, while Jose Altuve and Isaac Paredes have combined for 124 hits and 62 RBI. 

Brandon Walter gets the ball for the Houston Astros, and he is 0-0 with a 0.00 ERA and 5 strikeouts this season. This will be Walter’s first career game against the Cleveland Guardians.

Cleveland Guardians Betting Preview

The Cleveland Guardians are 33-30 on the year and play the Reds, Mariners, and Giants next. The Cleveland Guardians are batting .233 on the season, have a .306 OBP, and a .376 slugging percentage. The Cleveland Guardians’ pitching staff has a 3.98 ERA and a 1.37 WHIP. Jose Ramirez leads the Cleveland Guardians with 77 hits and 31 RBI, while Steven Kwan and Carlos Santana have combined for 127 hits and 50 RBI.

Tanner Bibee gets the ball for the Cleveland Guardians, and he is 4-6 with a 3.89 ERA and 56 strikeouts this season. This will be Bibee’s second career game against the Houston Astros.

Why the Cleveland Guardians will win

• The Guardians have won each of their last eight Sunday day home games against AL West opponents.
• The Astros have lost seven of their last eight games after going to extra innings.
• The favorites have covered the run line in each of the Guardians’ last four games at Progressive Field.
• The Astros have failed to cover the run line in five of their last six games after going to extra innings.

Why the Houston Astros will win

• The Astros have won five of their last six games as underdogs.
• The Guardians have lost each of their last seven Sunday games against teams that held a winning record.
• The Guardians have failed to cover the run line in 11 of their last 12 games as favorites after going to extra innings.
• The Astros have covered the run line in 11 of their last 12 games as underdogs against American League opponents.
• The Astros have led after 5 innings in each of their last four games against the Guardians at Progressive Field.

Cleveland Guardians Player Prop Facts

• Jose Ramirez has hit a home run in each of the Guardians’ last three day games.
• Jose Ramirez has scored at least one run in each of the Guardians’ last four day games against AL West opponents that held a winning record.
• Carlos Santana has recorded at least one hit in each of his last 10 appearances with the Guardians as home favorites against AL West opponents.
• Jose Ramirez has recorded at least one Single in each of the Guardians’ last six day games.
• Nolan Jones has recorded at least one RBI in each of the Guardians’ last four games as home favorites.
• Will Brennan has recorded at least one Double in each of his last three appearances with the Guardians as favorites against AL opponents.
• Jose Ramirez ranks 4th amongst qualified players for Batting Average (.333) this season.

Houston Astros Player Prop Facts

• Christian Walker has hit a home run in each of the Astros’ last two games as underdogs.
• Jeremy Pena has recorded at least one RBI in five of the Astros’ last six games against AL Central opponents that held a winning record.
• Jose Altuve has recorded two or more hits in each of his last six appearances with the Astros as road underdogs against the Guardians.
• Jose Altuve has recorded at least one Double in each of his last four appearances with the Astros as underdogs against the Guardians.
• Jeremy Pena has recorded at least one Single in each of the Astros’ last nine games against AL Central opponents that held a winning record.
• Yordan Alvarez has scored at least one run in each of his last six road appearances against AL opponents that held a winning record.
• Jeremy Pena ranks 5th amongst qualified players for Batting Average (.321) this season.

Houston Astros vs Cleveland Guardians Prediction

I’m not sure what we’re going to get from Walter, who will make his second career start and has pitched just five innings in the last two seasons. Bibee is easily the more trustworthy pitcher given the larger sample size, and he’s been good at home with a 2.43 ERA and .234 allowed batting average in 29.2 innings. However, the Astros are rolling right now with wins in 10 of their last 13 games, and that’s the type of success I want to grab in the plus money role. Until the tickets stop cashing and the Astros cool off, I’m going to throw the pitching matchups out the window and grab the favorable prices when I can. Give me the Astros.