Baltimore Orioles vs Seattle Mariners Prediction 6/5/25 MLB Picks

In this article, we will formulate an Orioles vs White Sox prediction for this MLB game on Thursday, June 5, at T-Mobile Park in Seattle, Washington. Let’s take a look at the prediction for this MLB matchup.

Baltimore Orioles Betting Preview

The Baltimore Orioles (24-36, 12-19 Away) are on a five-game winning streak for the first time this season after sweeping the Chicago White Sox and beating the Seattle Mariners in the opening two games of the current series. In last night’s 3-2 victory, Heston Kjerstad led the offense with two RBI, while Cade Povich pitched for 5.1 innings in a no-decision, allowing two runs on four hits with five strikeouts and one walk. Yennier Cano was credited with the win. 

This year, the Orioles average 3.83 runs per game (25th in the MLB) on a .237/.303/.386 triple-slash. When it comes to pitching, the Orioles’ staff has a 5.14 ERA (28th) and 1.44 WHIP (27th). Cedric Mullins leads the Orioles with a .232 batting average, ten home runs, and 31 RBI this season.

The projected starting pitcher for the Orioles is Zach Eflin, who is 4-2 in ten starts this season, with a 4.46 ERA and 1.09 WHIP in 40.1 innings.

Seattle Mariners Betting Preview

The Seattle Mariners (32-28, 16-16 Away) responded to series losses against the Astros and Nationals with a win over the Minnesota Twins, but then lost the opening two games of the series against Baltimore. Following a 5-1 loss, the Mariners fell short 3-2 in Game 2 on Wednesday. Emerson Hancock pitched for 5.2 innings in a no-decision, allowing one run on two hits with six strikeouts and two walks. Carlos Vargas took the loss. 

This season, the Mariners average 4.43 runs per game (12th in the MLB) on a .235/.319/.392 triple-slash. When it comes to pitching, the Mariners’ staff has a 3.87 ERA (14th) and 1.32 WHIP (21st). Cal Raleigh leads the Mariners with a .264 batting average, 23 home runs, and 46 RBI this season.

Bryan Woo will take the mound for the Mariners on Thursday. The 25-year-old right-hander has a 5-2 record in 11 starts this year with a 2.82 ERA and 0.95 WHIP in 70.1 innings.

Why the Mariners will beat the Orioles

• The Orioles have lost nine of their last 10 day games against American League opponents that held a winning record.
• The Mariners have won seven of their last eight day games at T-Mobile Park following a loss.
• The Orioles have failed to cover the run line each of their last five day games against American League opponents that held a winning record.
• The Mariners have covered the run line in four of their last five day games against AL East opponents.

Total Runs Facts

• Each of the Orioles’ last five games have gone UNDER the total runs line.
• Each of the Mariners’ last four home games against AL East opponents have gone UNDER the total runs line.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Mariners’ last four day games at T-Mobile Park.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in six of the Orioles’ last seven games at T-Mobile Park.

Matchup/League Facts

• The Mariners rank T27th in the league for triples this season (3).
• The Mariners rank 6th in the league for home runs this season (80).
• The Orioles rank 27th in the league for opponent batting average this season (.269).
• The Orioles rank 27th in the league for runs allowed this season (318).

Orioles vs Mariners Prediction

The Orioles won eight of the previous ten H2H encounters, including five of the last six. However, I am backing the Mariners to get a win here and avoid a sweep. Seattle will start Woo, who is having a very strong season so far, allowing more than three runs on just two occasions. Woo has five consecutive quality starts, and I am backing him to add one more on Thursday. Zach Eflin, on the other hand, hasn’t pitched very well in May, as he allowed multiple runs in three of four starts, but did post a shutout in his latest start against the White Sox. Still, I am going with Seattle to win.