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Tampa Bay Rays vs Houston Astros Prediction 5/31/25 MLB Picks

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Houston Astros (31-26) vs Tampa Bay Rays (29-28)

May 31, 2025 at 04:10 PM EDT

The Line: Betting Odds: Houston Astros -120 / Tampa Bay Rays +100 — Over/Under: 8.5

(Get latest betting odds)

The Tampa Bay Rays and the Houston Astros meet Saturday in MLB action from Daikin Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Tampa Bay Rays vs. Houston Astros prediction.

Starting Pitching Matchup

The Tampa Bay Rays will start Zack Littell here and Littell is 4-5 with a 3.97 ERA and 42 strikeouts this season. In his career, Littell is 2-0 with a 2.61 ERA and 16 strikeouts against the Astros. The Houston Astros will send out Colton Gordon for the start here and Gordon is 0-0 with a 5.52 ERA and 14 strikeouts this season. This will be Gordon’s second career start against the Astros.

Tampa Bay Rays Recap

The Tampa Bay Rays come into this game looking to rebound from a 2-1 loss at the hands of the Astros from Friday’s matchup, slipping to 29-28 on the year as a result. After this series, the Rays will head home for a series with the Texas Rangers.

Rays Looking To Rebound

Jonathan Aranda has 55 hits with a team-high 11 doubles, 7 home runs and 31 RBIs. Brandon Lowe has 49 hits with 11 homers and 30 RBIs as well while Junior Caminero has 52 hits with 11 doubles, a team-high 11 home runs and 32 RBIs. Yandy Diaz has 50 hits with 11 doubles, 7 homers and 31 RBIs and Kameron Misner has 35 hits with 8 doubles, 4 homers and 17 RBIs as well while Christopher Morel has 50 strikeouts while Lowe has 54 strikeouts and Misner has 49 K’s as well this season. Jose Caballero has 18 stolen bases while Taylor Walls has 7 stolen bases and Chandler Simpson has 19 stolen bases as well this season.

Why the Tampa Bay Rays will win

  • The Rays have won each of their last six day games against American League opponents.
  • The Astros have lost three of their last four games as favorites against the Rays following a home win.
  • The underdogs have covered the run line in each of the last seven games between the Rays and Astros.
  • The Astros have failed to cover the run line in eight of their last nine games as favorites after playing the previous day.

Tampa Bay Rays Player Prop Facts

  • Brandon Lowe has hit a home run in each of the Rays’ last three day games.
  • Yandy Diaz has recorded at least one RBI in five of his last six road appearances.
  • Brandon Lowe has recorded at least one Single in seven of his last eight road appearances.
  • Brandon Lowe has scored at least one run in each of his last eight appearances.
  • Brandon Lowe has recorded at least one hit in each of his last 14 appearances against AL opponents.

Houston Astros Recap

The Houston Astros come into this game looking to add on to their win over Tampa Bay from Friday’s matchup to improve to 31-26 this season. After this series, the Astros will head on the road for a series against the Pittsburgh Pirates.

Astros Win 5 Of Their Last 6 Games

Jose Altuve has 57 hits including 9 home runs and 22 RBIs. Jeremy Pena also has 65 hits with 7 homers and 27 RBIs with 9 stolen bases while Yordan Alvarez has 4 doubles and 18 RBIs with 21 strikeouts as well. Jake Meyers has 9 doubles as well and Christian Walker has also accrued a team-high 62 strikeouts so far this season. Altuve also has 4 stolen bases while Jake Meyers has 8 stolen bases this season. Isaac Paredes also has a team-high 11 home runs with 32 RBIs of his own and Cam Smith has contributed 3 homers and 17 RBIs.

Why the Houston Astros will win

  • The Astros have won each of their last seven day games against AL East opponents following a win.
  • The Rays have lost five of their last six road games against AL West opponents that held a winning record.
  • The Astros have covered the run line in each of their last seven day games against AL East opponents following a win.
  • The Rays have failed to cover the run line in each of their last four games against AL West opponents following a loss.

Houston Astros Player Prop Facts

  • Yainer Diaz has hit a home run in each of the Astros’ last two games as favorites.
  • Yainer Diaz has scored a run in each of the Astros’ last four games as home favorites against AL East opponents.
  • Christian Walker has recorded at least one Single in each of his last eight appearances with his team as a favorite against AL East opponents.
  • Yainer Diaz has recorded at least one hit in each of the Astros’ last 16 games against AL East opponents that held a winning record.
  • Yordan Alvarez has recorded a Double in each of his last five Saturday appearances at Daikin Park.
  • Yordan Alvarez has recorded an RBI in each of his last five appearances with the Astros as home favorites.
  • Jeremy Pena ranks T10th in the league in Hits (65) this season.

Total Runs Facts

  • Five of the Astros’ last six home games against AL East opponents have gone UNDER the total runs line.
  • Twelve of the Rays’ last 15 road games against AL West opponents have gone UNDER the total runs line.

Tampa Bay Rays vs. Houston Astros Prediction

I’m backing the Rays here. Framber Valdez was able to stifle the Rays on Friday, but realistically, the Rays have been doing a pretty good job as of late when it comes to smashing left-handed pitching and Gordon is a far cry from the likes of Framber Valdez. Zack Littell has been rolling in recent starts and I think the Rays have a bullpen edge too. Give me the Rays here.

Chris Ruffolo's Pick: Tampa Bay Rays +100

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