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Colorado Rockies vs Chicago Cubs Prediction 5/28/25 MLB Picks

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Chicago Cubs (34-21) vs Colorado Rockies (9-46)

May 28, 2025 at 08:05 PM EDT

The Line: Betting Odds: Chicago Cubs -355 / Colorado Rockies +280 — Over/Under: 8

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In this article, we will formulate a Rockies vs Cubs prediction for this MLB game on Wednesday, May 28, at Wrigley Field in Chicago, Illinois. Let’s take a look at the prediction for this MLB matchup.

Colorado Rockies Betting Preview

The Colorado Rockies (9-46, 3-24 Away) were swept by the Philadelphia Phillies and lost the series to the New York Yankees at home, before losing the opening two games of the current series against the Chicago Cubs. Following a 3-1 loss, the Rockies fell short 4-3 to the Cubs in extra innings last night. Brenton Doyle led the offense with two RBI, while German Marquez pitched for 6.0 innings in a no-decision, allowing two runs on seven hits with six strikeouts and one walk. Tyler Kinley took the loss.

This year, the Rockies average 3.20 runs per game (29th in the MLB) on a .219/.285/.359 triple-slash. When it comes to pitching, the Rockies’ staff has a 5.67 ERA (30th) and 1.60 WHIP (30th). Hunter Goodman leads the Rockies with a .276 batting average, seven home runs, and 31 RBI this season.

The projected starting pitcher for the Rockies is Tanner Gordon, who is 1-1 in two starts this season, with a 4.38 ERA and 1.38 WHIP in 12.1 innings.

Chicago Cubs Betting Preview

The Chicago Cubs (34-21, 17-10 Home) won the previous four series, and now added one more following two wins over the Colorado Rockies. Prior to this series, the Cubs defeated the Marlins (twice), swept the White Sox, and beat the Reds. Chicago won nine of the previous 11 games. In Game 2 victory against Colorado on Tuesday, Cade Horton pitched for 6.0 innings in a no-decision, allowing two runs on four hits with six strikeouts and one walk. Chris Flexen was credited with the win.

This season, the Cubs average 6.00 runs per game (1st in the MLB) on a .263/.336/.455 triple-slash. When it comes to pitching, the Cubs’ staff has a 4.01 ERA (17th) and 1.29 WHIP (18th). Seiya Suzuki leads the Cubs with a .272 batting average, 14 home runs, and 50 RBI this season.

Matthew Boyd will take the mound for the Cubs on Wednesday. The 34-year-old left-hander has a 4-2 record in ten starts this year with a 3.42 ERA and 1.32 WHIP in 55.1 innings.

Total Runs Facts

  • Four of the Rockies’ last five road games against NL Central opponents have gone UNDER the total runs line.
  • Four of the Cubs’ last five games following an extra innings win have gone UNDER the total runs line.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in 10 of the Cubs’ last 11 games.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in five of the Rockies’ last six night games against NL Central opponents.

Matchup/League Facts

  • The Cubs rank 1st in the league for RBIs this season (320).
  • The Cubs rank 2nd in the league for triples this season (13).
  • The Rockies rank 30th in the league for strikeouts against this season (538).
  • The Rockies rank 30th in the league for ERA this season (5.61).

Rockies vs Cubs Prediction

The Cubs won eight of the previous ten H2H encounters, including the last three. I am going with Over in this one after the opening two games failed to produce more than seven runs. Tanner Gordon allowed six earned runs in his two starts this season, and I am sure the Cubs are going to score 3+ against him in the first five or six innings. After all, the Cubs have the best offense in the MLB, and the Rockies have the worst defense. Matthew Boyd, on the other hand, allowed multiple runs in each of his previous eight starts, and I don’t think that will change on Wednesday. Back the Over.

Oliver Zivic's Pick: Over 7.5

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