Boston Red Sox vs Milwaukee Brewers Prediction 5/28/25 MLB Picks

In this article, we will formulate a Red Sox vs Brewers prediction for this MLB game on Wednesday, May 28, at American Family Field in Milwaukee, Wisconsin. Let’s take a look at the prediction for this MLB matchup.

Boston Red Sox Betting Preview

The Boston Red Sox (27-30, 11-16 Away) matched their longest losing skid of the season at four after succumbing to a 5-1 defeat against the Milwaukee Brewers in Game 2 of the series last night. Boston lost the opening game 3-2, while prior to this series, the Red Sox had lost two in a row to the Baltimore Orioles and earned only a split. In Tuesday’s 5-1 extra-innings defeat, Richard Fitts pitched for 3.0 innings in a no-decision, allowing no runs on two hits with two strikeouts and one walk. Liam Hendriks took the loss.

This season, the Red Sox average 4.80 runs per game (7th in the MLB) on a .254/.326/.422 triple-slash. When it comes to pitching, the Red Sox’s staff has a 4.01 ERA (16th) and 1.34 WHIP (21st). Rafael Devers leads the Red Sox with a .286 batting average, 12 home runs, and 48 RBI this season.

Brayan Bello will take the mound for the Red Sox on Wednesday. The 26-year-old right-hander has a 2-1 record in seven starts this year with a 4.08 ERA and 1.70 WHIP in 35.1 innings.

Milwaukee Brewers Betting Preview

The Milwaukee Brewers (28-28, 17-10 Home) beat the Baltimore Orioles, split with the Pittsburgh Pirates, and won the first two games of the series against the Boston Red Sox. Following a narrow 3-2 win in Game 1, the Brewers needed ten innings to see off the Red Sox in Game 2, but did it thanks to Christian Yelich, who blasted a walk-off grand slam off Liam Hendricks to make it 5-1. Aaron Civale pitched for 5.0 innings in a no-decision, allowing one run on three hits with four strikeouts and one walk. Rob Zastryzny was credited with the win.

This year, the Brewers average 4.27 runs per game (14th in the MLB) on a .232/.311/.353 triple-slash. When it comes to pitching, the Brewers’ staff has a 4.07 ERA (22nd) and 1.35 WHIP (22nd). Christian Yelich leads the Brewers with a .210 batting average, ten home runs, and 34 RBI this season.

The projected starting pitcher for the Brewers is Freddy Peralta, who is 5-3 in 11 starts this season, with a 2.55 ERA and 1.12 WHIP in 60.0 innings.

Why the Brewers will beat the Red Sox

• The Red Sox have lost each of their last six road games against National League opponents.
• The Brewers have won each of their last 10 Wednesday games as home favorites against American League opponents.
• The Red Sox have failed to cover the run line in each of their last six road games against National League opponents after playing the previous day.
• The home team has covered the run line in each of the Brewers’ last four games.
• The Red Sox have trailed after 3 innings in five of their last six games as road underdogs against National League opponents.
• The Red Sox have trailed after 5 innings in five of their last six road games against National League opponents.

Total Runs Facts

• Each of the Red Sox’s last five games against National League opponents have gone UNDER the total runs line.
• Each of the last three games between the Red Sox and Brewers have gone UNDER the total runs line.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Brewers’ last four games as home favorites.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in four of the Red Sox’s last five day games against National League opponents.

Matchup/League Facts

• The Brewers rank 28th in the league for walks allowed this season (208).
• The Brewers rank T26th in the league for doubles this season (74).
• The Red Sox rank 28th in the league for strikeouts against this season (509).
• The Red Sox are one of only four teams in the league to rank top 10 in both steals and batting average this season.

Red Sox vs Brewers Prediction

The Brewers won six of the previous ten H2H encounters, including four of the last five. I am going with another win for Milwaukee because of Freddy Peralta, who has a clear advantage over Brayan Bello. Peralta allowed more than two runs only twice this season, while he surrendered two runs in his last two starts. Bello, on the other hand, allowed multiple runs in his previous three starts, 11 in total in that stretch. Back the Brewers to win and sweep the series.