Chicago White Sox vs New York Mets Prediction 5/26/25 MLB Picks

The Chicago White Sox and the New York Mets meet Monday in MLB action from Citi Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Chicago White Sox vs. New York Mets prediction.

Starting Pitching Matchup

The Chicago White Sox will send out Adrian Houser for the start here, and Houser is 1-0 with a 0.00 ERA and 2 strikeouts this season. In his career, Houser is 1-1 with a 3.52 ERA and 8 strikeouts against the Mets. Clay Holmes will start this one for the Mets and is 5-3 with a 3.13 ERA and 53 strikeouts this season. This will be Holmes’ first career start against the White Sox.

Chicago White Sox Recap

The Chicago White Sox come into this game looking to bounce back from a 5-4 loss at the hands of the Texas Rangers last time out to fall to 17-36 on the year. After this series, the White Sox will head on the road for a series against the Baltimore Orioles.

White Sox Pick Up Rare Series Win

Lenyn Sosa leads the White Sox with 49 hits, including 9 doubles and 16 RBIs. Andrew Benintendi has 21 hits, including 5 home runs, 15 RBIs, and a .219 batting average, while Miguel Vargas has a team-high 12 doubles, 7 home runs, and 23 RBIs. Brooks Baldwin has also added 16 RBIs, while Luis Robert Jr. has a team-high 20 stolen bases along with 20 RBIs so far this season. Andrew Vaughn has 5 home runs and 19 RBIs as well as 8 doubles this season.

Why the Chicago White Sox will win

• The White Sox have won each of their last five games as underdogs following a home loss.
• The Mets have lost four of their last five games as favorites against American League opponents.
• The Mets have failed to cover the run line in each of their last eight day games against AL Central opponents following a home win.
• The road team has covered the run line in 10 of the last 11 games between the White Sox and Mets.

Chicago White Sox Player Prop Facts

• Miguel Vargas has hit at least one home run in four of the White Sox’s last five games against NL opponents that held a winning record.
• Miguel Vargas has recorded at least one RBI in each of the White Sox’s last five games against NL opponents that held a winning record.
• Andrew Benintendi has scored a run in each of his last four appearances against opponents that held a winning record.
• Andrew Vaughn has recorded at least one hit in each of his last 12 Monday appearances with the White Sox as underdogs.
• Korey Lee has recorded a Double in each of his three previous appearances with the White Sox as road underdogs against NL East opponents.
• Korey Lee has recorded a Single in each of his last five appearances with the White Sox as underdogs against NL East opponents.
• Luis Robert ranks 1st in the league in Steals (20) this season.

New York Mets Recap

The New York Mets come into this game looking to add on to their 3-1 win over the Los Angeles Dodgers from Sunday’s series finale to improve their record to 32-21 on the year. After this series, the Mets will welcome the Colorado Rockies to town.

Mets Pick Up Big Series Win Vs. Dodgers

Pete Alonso has 57 hits with 16 doubles, 10 home runs, 40 RBIs, and a .291 batting average, while Juan Soto has 45 hits with 10 doubles, 8 home runs, and 24 RBIs on the year. Francisco Lindor has 57 hits with 9 stolen bases along with 9 doubles, 10 home runs, and 29 RBIs, while Mark Vientos has 5 home runs, 18 RBIs, but 41 strikeouts so far this season. Brandon Nimmo has also added 38 hits with 9 doubles and 8 home runs, and 27 RBIs this season. Luis Torrens has also chipped in 9 doubles, and Luisangel Acuna has 11 stolen bases as well this season.

Why the New York Mets will win

• The White Sox have lost each of their last eight road games against teams that held a winning record.
• The Mets have won each of their last seven home games against American League opponents.
• The White Sox have failed to cover the run line in each of their last eight Monday day road games.
• The home team has covered the run line in each of the White Sox’s last five games.

New York Mets Player Prop Facts

• Juan Soto has hit a home run in four of his last five appearances with his team as a favorite against AL Central opponents.
• Francisco Lindor has recorded a Double in four of the Mets’ last five home games against AL opponents.
• Francisco Lindor has recorded at least one RBI in each of the Mets’ last four day games.
• Juan Soto has recorded a Single in each of his last nine appearances against opponents that held a losing record.
• Francisco Lindor has scored at least one run in seven of the Mets’ last eight home games against AL opponents.
• Starling Marte has recorded at least one hit in each of his last 12 appearances in day games against AL Central teams that held a losing record.
• Clay Holmes ranks T9th in the league for Wins (5) this season.

Total Runs Facts

• Each of the Mets’ last seven day games against American League opponents have gone UNDER the total runs line.
• Nine of the White Sox’s last 10 games as underdogs against the Mets have gone UNDER the total runs line.

Chicago White Sox vs. New York Mets Prediction

I’m on the Mets here. I know the White Sox had a solid series this past weekend against Texas, but the Mets looked really good in their own right against a tougher opponent in the Dodgers, and I’m not sold on Adrian Houser after one start back. The Mets know what he’s tossing, and I think that the White Sox will have trouble matching against Clay Holmes here. Give me the Mets in this one.