Detroit Tigers vs St. Louis Cardinals Prediction 5/20/25 MLB Picks

In this article, we will formulate a Tigers vs Cardinals prediction for this MLB game on Tuesday, May 20, at Busch Stadium in St. Louis, Missouri. Let’s take a look at the prediction for this MLB matchup.

Detroit Tigers Betting Preview

The Detroit Tigers (31-17, 14-12 Away) swept the Boston Red Sox and beat the Toronto Blue Jays before this series against the St. Louis Cardinals. The Tigers opened it with an 11-4 defeat last night, their highest amount of runs allowed in a game this season. Keider Montero pitched for 5.2 innings in a no-decision, allowing five runs on eight hits with three strikeouts and two walks. Sean Guenther took the loss.

This season, the Tigers average 5.35 runs per game (4th in the MLB) on a .260/.332/.422 triple-slash. When it comes to pitching, the Tigers’ staff has a 3.36 ERA (6th) and 1.18 WHIP (8th). Spencer Torkelson leads the Tigers with a .246 batting average, 12 home runs, and 38 RBI this season.

Tarik Skubal will take the mound for the Tigers on Tuesday. The 28-year-old left-hander has a 4-2 record in nine starts this year with a 2.67 ERA and 0.93 WHIP in 54.0 innings.

St. Louis Cardinals Betting Preview

The St. Louis Cardinals (27-21, 16-6 Home) are playing their best baseball of the season after winning 13 of the previous 15 games. They won seven straight series, including the most recent one over the Kansas City Royals, and then opened the current series against the Tigers with an 11-4 victory on Monday. Ivan Herrera, Jordan Walker, and Pedro Pages led the team with two RBI apiece, while Sonny Gray got the win after allowing no runs on three hits with ten strikeouts and one walk across 6.0 innings of work.

This year, the Cardinals average 4.90 runs per game (6th in the MLB) on a .266/.337/.409 triple-slash. When it comes to pitching, the Cardinals’ staff has a 3.68 ERA (12th) and 1.22 WHIP (9th). Willson Contreras leads the Cardinals with a .249 batting average, six home runs, and 27 RBI this season.

The projected starting pitcher for the Cardinals is Erick Fedde, who is 3-3 in nine starts this season, with a 3.44 ERA and 1.30 WHIP in 52.1 innings.

Total Runs Facts

• Each of the Tigers’ last four games against National League opponents have gone OVER the total runs line.
• Each of the last four games between the Tigers and Cardinals at Busch Stadium have gone OVER the total runs line.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Cardinals’ last eight Tuesday night games.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in eight of the Tigers’ last 10 games against NL Central opponents.

Matchup/League Facts

• The Cardinals rank 2nd in the league for batting average this season (.266).
• The Cardinals rank 2nd in the league for home runs allowed this season (35).
• The Tigers rank T4th in the league for hits this season (426).
• The Tigers rank T4th in the league for RBIs this season (245).

Tigers vs Cardinals Prediction

The Tigers won six of the previous ten H2H encounters, but the Cards were better in three of the last five. Although I don’t think the teams will combine for 15 runs like they did last night, I am still going with Over, despite the fact that Skubal starts for the Tigers. Skubal struggled in his previous start, and the Cardinals are red-hot recently, so I wouldn’t bet on Skubal and a quality start here. Erick Fedde, on the other hand, was impressive in his last two starts; he even recorded a complete-game shutout against his former team, the Nationals. It’s hard to expect Fedded to have another shutout game, so I am going with Over.