Seattle Mariners vs San Diego Padres Prediction 5/18/25 MLB Picks

In this article, we will formulate a Mariners vs Padres prediction for this MLB game on Sunday, May 18, at PETCO Park in San Diego, California. Let’s take a look at the prediction for this MLB matchup.

Seattle Mariners Betting Preview

The Seattle Mariners (25-19, 12-8 Away) beat the Athletics and then were swept by the Blue Jays and lost the series to the Yankees at home, losing five of six games along the way. However, the Mariners responded very well with a pair of road victories in the current series against the Padres. They displayed some excellent defense in 5-1 and 4-1 wins. Last night, in a 4-1 victory, Dylan Moore led the offense with two RBI, while Emerson Hancock pitched for 4.2 innings in a no-decision, allowing one run on six hits with three strikeouts and one walk. Gabe Speier was credited with the win.

This season, the Mariners average 4.79 runs per game (9th in the MLB) on a .240/.328/.403 triple-slash. When it comes to pitching, the Mariners’ staff has a 3.84 ERA (13th) and 1.33 WHIP (21st). Cal Raleigh leads the Mariners with a .253 batting average, 15 home runs, and 31 RBI this season.

Bryan Woo will take the mound for the Mariners on Sunday. The 25-year-old right-hander has a 4-1 record in eight starts this year with a 2.84 ERA and 0.89 WHIP in 50.2 innings.

San Diego Padres Betting Preview

The San Diego Padres (27-17, 16-7 Home) defeated the Rockies and Angels following a series loss to the New York Yankees. The Padres were favorites in the opening two games of the series against the Mariners, but lost both, and now are hoping to avoid being swept on Sunday. In Saturday’s 4-1 defeat, Nick Pivetta pitched for 6.0 innings in a no-decision, allowing one run on two hits with seven strikeouts and one walk. Adrian Morejon took the loss.

This year, the Padres average 4.58 runs per game (13th in the MLB) on a .263/.331/.399 triple-slash. When it comes to pitching, the Padres’ staff has a 3.34 ERA (6th) and 1.17 WHIP (6th). Fernando Tatis Jr. leads the Padres with a .305 batting average, 11 home runs, and 26 RBI this season.

The projected starting pitcher for the Padres is Michael King, who is 4-1 in nine starts this season, with a 2.32 ERA and 0.99 WHIP in 44.1 innings.

Total Runs Facts

• Each of the Mariners’ last five day games against National League opponents have gone OVER the total runs line.
• Each of the Padres’ last four day games against AL West opponents have gone UNDER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in 10 of the Mariners’ last 11 day games against National League opponents.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in 10 of the Padres’ last 11 day games against AL West opponents.

Matchup/League Facts

• The Padres rank 3rd in the league for opponent batting average this season (.217).
• The Padres rank 3rd in the league for hits allowed this season (311).
• The Mariners are one of only four teams in the league to rank top 10 in both steals and home runs this season.
• The Mariners rank T5th in the league for walks this season (174).

Mariners vs Padres Prediction

The Mariners won eight of the previous ten H2H encounters, including seven of the last eight. Although I believe the Padres will not be swept at home here, I am opting for Under instead of backing the hosts. Bryan Woo struggled against the A’s recently, but recorded shutouts in a start before and a start after that one. Woo allowed a .095 BA in 21 at-bats against the Padres, while Michael King allowed a .214 BA in 56 at-bats against the Mariners. King surrendered just seven runs in his previous six starts. He allowed more than two runs only twice this year. Go with Under.