San Diego Padres vs Colorado Rockies Prediction 5/9/25 MLB Picks

The projected starting pitcher for the Padres is Randy Vasquez, who is 1-3 in seven starts this season, with a 3.90 ERA and 1.67 WHIP in 32.1 innings.

Colorado Rockies Betting Preview

The Colorado Rockies (6-31, 4-14 Home) are on a six-game losing skid after losing the series to the San Francisco Giants and getting swept by the Detroit Tigers. The Rox fought in Game 1 against Detroit but lost in extra innings, while they were destroyed in the following two duels. In the latest 11-1 defeat, Tanner Gordon took the loss after allowing seven runs (four earned) on nine hits with four strikeouts and one walk in 6.1 innings.

This season, the Rockies average 3.11 runs per game (30th in the MLB) on a .211/.280/.343 triple-slash. When it comes to pitching, the Rockies’ staff has a 5.47 ERA (28th) and 1.56 WHIP (29th). Hunter Goodman leads the Rockies with a .264 batting average, five home runs, and 18 RBI this season.

Antonio Senzatela will take the mound for the Rockies on Friday. The 30-year-old right-hander has a 1-5 record in seven starts this year with a 5.50 ERA and 1.86 WHIP in 34.1 innings.

Why the Padres will cover

• The Rockies have lost 14 of their last 15 night games following a loss.
• The Padres have won each of their last nine games as favorites against National League opponents.
• The Padres have covered the run line each of their last eight games against National League opponents that held a losing record.
• The Rockies have failed to cover the run line in each of their last six games.
• The Padres have led after 3 innings in five of their last six games as favorites against National League opponents.
• The Padres have led after 5 innings in each of their last five games against NL West opponents.

Total Runs Facts

• Each of the Rockies' last five games have gone OVER the total runs line.
• Four of the Padres' last five games have gone UNDER the total runs line.
• The 'Inning 1 UNDER 0.5 runs' market has hit in each of the Padres' last four night games.
• The 'Inning 1 UNDER 0.5 runs' market has hit in nine of the last 12 games between the Padres and Rockies.

Matchup/League Facts

• The Rockies rank T1st in the league for triples this season (10).
• The Rockies rank 30th in the league for RBIs this season (114).
• The Padres rank 1st in the league for runs allowed this season (114).
• The Padres rank 2nd in the league for opponent batting average this season (.211).

Padres vs Rockies Prediction

The Padres won six of the previous ten H2H encounters. This season, the Padres are 3-0 against the Rox, and they haven't allowed a single run in that series sweep. I don't expect another zero on the scoreboard for the Rockies, but I do expect the Padres to dominate this series and open it with a comfortable win on Friday. Senzatela allowed 4+ runs in four of his previous five starts, while Vasquez kept the opponents under two runs in three of his last five starts. Senzatela allowed a .286 BA in 63 at-bats against the Padres in his career. Back the Padres to win and cover the run line.