Houston Astros vs Milwaukee Brewers Prediction 5/6/25 MLB Picks

Astros Drop 4 Of Their Last 5

Jose Altuve has 35 hits, including 4 home runs and 14 RBIs. Jeremy Pena also has 36 hits with 4 homers and 12 RBIs with 5 stolen bases, while Yordan Alvarez has 4 doubles and a team-high 18 RBIs with 21 strikeouts as well. Jake Meyers has 5 doubles as well, and Christian Walker has also accrued a team-high 40 strikeouts so far this season. Altuve also has 3 stolen bases while Jake Meyers has a team-high 7 stolen bases this season. Isaac Paredes also has a team-high 4 home runs with 14 RBIs of his own, and Cam Smith has contributed 3 homers and 10 RBIs.

Why the Houston Astros will win

• The Astros have won five of their last six games as road underdogs following a loss.
• The Brewers have lost five of their last seven games as favorites against the Astros following a win.
• The Astros have covered the run line in 14 of their last 16 games as road underdogs following a loss.
• The Brewers have failed to cover the run line in four of their last five night games against the Astros following a win.

Houston Astros Player Prop Facts

• Jake Meyers has recorded at least one RBI in four of his five previous appearances against the Brewers after playing the previous day.
• Jose Altuve has scored at least one run in four of the Astros' last five games as road underdogs.
• Jeremy Pena has recorded at least one Single in each of the Astros' last nine games.
• Isaac Paredes has recorded at least one hit in each of the Astros' last nine night games.
• Yordan Alvarez has hit at least one home run in three of his eight previous appearances against the Brewers.

Milwaukee Brewers Recap

The Milwaukee Brewers come into this game looking to build on their win over Houston from Monday’s series opener to improve to 18-18 on the year. After this series, the Brewers will head out on the road for a set against the Tampa Bay Rays.

Brewers Win Back-To-Back Games

Brice Turang has a team-high 41 hits with 3 home runs, 16 RBIs, and 8 stolen bases, while Jackson Chourio has 39 hits with a team-high 12 doubles, 6 home runs, and 24 RBIs, and Sal Frelick has 35 hits as well as 2 triples and 7 stolen bases so far this season. Christian Yelich also has 7 stolen bases with 6 homers and 25 RBIs while also adding 3 doubles. Yelich also has a team-high 38 strikeouts up to this point in the year. William Contreras has 3 homers and 19 RBIs as well this season.

Why the Milwaukee Brewers will win

• The Astros have lost nine of their last 10 road games against NL Central opponents.
• The Brewers have won 14 of their last 16 night games against American League opponents.
• The Astros have failed to cover the run line in 10 of their last 11 games against NL Central opponents.
• The Brewers have covered the run line in seven of their last eight night games against AL West opponents.

Milwaukee Brewers Player Prop Facts

• Rhys Hoskins has hit a home run in three of the Brewers' last six games as home favorites.
• William Contreras has recorded an RBI in five of the Brewers' last six games as favorites.
• William Contreras has scored at least one run in each of the Brewers' last six Tuesday night games as favorites.
• Brice Turang has recorded at least one Single in nine of his last 10 home appearances against AL opponents.
• Sal Frelick has recorded at least one hit in each of his last nine appearances with the Brewers as home favorites.

Total Runs Facts

• Each of the Astros' last eight games as underdogs against National League opponents have gone UNDER the total runs line.
• Six of the last seven games between the Astros and Brewers at American Family Field have gone UNDER the total runs line.

Houston Astros vs. Milwaukee Brewers Prediction

I’m on the Brewers here. The problem for the Astros here is that the offense has been so wildly inconsistent this season that it makes it hard to rely on them on any given night. The Brewers have been hit and miss in their own right, but they’ve navigated a rough first couple of weeks of the season and have been playing some really solid baseball and are starting to have the bounces go their way for a change. I think this could be a launching point for the Brewers to go on a bit of a run, and I think they grab another win in this one. Give me the Brewers here.