Houston Astros vs St. Louis Cardinals Prediction 4/14/25 MLB Picks

Astros Still Trying To Find Consistency After Alternating Wins & Losses In 10 Consecutive Games

Jose Altuve leads the Astros with 19 hits, including 3 home runs and 7 RBIs. Jeremy Pena also has a pair of homers and 4 stolen bases, while Yordan Alvarez has 2 doubles and a team-high 9 RBIs with 17 strikeouts as well. Brendan Rodgers has a pair of doubles, while Jake Meyers has a pair of doubles as well, and Christian Walker has also accrued a team-high 20 strikeouts so far this season. Altuve also has 3 stolen bases, while Jake Meyers has a team-high 5 stolen bases this season.

Why the Houston Astros will win

• The Cardinals have lost seven of their last eight night games against American League opponents following a win.
• The Astros have won four of their last five games at Busch Stadium.
• The Cardinals have failed to cover the run line in each of their last six night games against AL West opponents following a win.
• The Astros have covered the run line in seven of their last eight night games against teams that held a losing record.

Houston Astros Player Prop Facts

• Isaac Paredes has hit a home run in each of the Astros' last three games as favorites.
• Yainer Diaz has recorded at least one RBI in each of the Astros' last four games as favorites against the Cardinals.
• Framber Valdez has recorded a win in six of his last seven appearances with the Astros as favorites against NL opponents.
• Jose Altuve has scored at least one run in each of his last six road appearances against the Cardinals after playing the previous day.
• Framber Valdez has recorded seven or more strikeouts in five of his last six appearances with the Astros as favorites against NL opponents.
• Jose Altuve has recorded at least one Single in each of the Astros' last 10 games as favorites against NL opponents.
• Jose Altuve has recorded at least one hit in each of the Astros' last 10 games as favorites against NL opponents.
• Brendan Rodgers has recorded a Double in three of his last four appearances with his team as a favorite against NL Central opponents.
• Jake Meyers ranks T10th in the league in Steals (5) this season.

St. Louis Cardinals Recap

The St. Louis Cardinals come into this game looking to add on to their series win over the Philadelphia Phillies with a 7-0 win in Sunday’s series finale to improve to 7-8 this season. After this series, the Cardinals will head on the road for a series against the New York Mets.

Cardinals Also Trying To Search For Consistent Play

Brendan Donovan has a team-high 21 hits, along with 4 doubles, 2 home runs, and 10 RBIs, while Lars Nootbaar has 15 hits with a pair of home runs and a pair of stolen bases. Noaln Arenado also has 15 hits with 4 doubles of his own, and Victor Scott II has 14 hits with a pair of doubles, a triple, 7 RBIs, and a team-high 5 stolen bases. Ivan Herrera has also added a team-high 4 home runs and 11 RBIs so far this season.

Why the St. Louis Cardinals will win

• The Astros have lost each of their last six games as favorites following a win.
• The Cardinals have won seven of their last eight games as home underdogs.
• The Astros have failed to cover the run line in each of their last seven games against NL Central opponents.
• The Cardinals have covered the run line in nine of their last 10 games as underdogs after playing the previous day.

St. Louis Cardinals Player Prop Facts

• Nolan Arenado has recorded a Double in each of the Cardinals' last three games against AL opponents that held a losing record.
• Sonny Gray has recorded a win in four of his last five home appearances against AL opponents.
• Nolan Arenado has recorded at least one RBI in six of the Cardinals' last seven home games against AL opponents.
• Nolan Arenado has scored at least one run in each of his last six home appearances against AL opponents that held a losing record.
• Brendan Donovan has recorded at least one Single in each of the Cardinals' last 10 games against opponents that held a losing record.
• Sonny Gray has recorded six or more strikeouts in each of his last 10 appearances against AL opponents.
• Brendan Donovan has recorded at least one hit in each of the Cardinals' last 13 games as underdogs.
• Nolan Gorman has hit at least one home run in three of his last four appearances in night games against AL teams that held a losing record.
• Brendan Donovan ranks T4th in the league in Hits (21) this season.

Total Runs Facts

• Each of the Cardinals' last five night games after playing the previous day have gone OVER the total runs line.
• Each of the Astros' last four road games against National League opponents have gone UNDER the total runs line.

Houston Astros vs. St. Louis Cardinals Prediction

I’m on the Cardinals in this one. I get why the Astros would be favored on the road here with an ace-level pitcher in Valdez going, but I like what the Cardinals drummed up this past weekend against the Phillies, and the pitching for the Cards has been elite over the last week. Houston’s offense has been inconsistent at the best of times this season, and I think they could be in trouble here again. Give me the Cardinals here.