Houston Astros vs Minnesota Twins Prediction 4/5/25 MLB Picks

-Recent Betting trends and streaks involving Houston

-Recent Betting trends and streaks involving Minnesota

-Recent betting trends in games played between Houston and Minnesota

-A summary that ties it all together produces a favorable betting outcome for Today’s Game between the Astros and Twins. 

Slow Start For Twins

It has been a slow start for the Twins, and they are coming off a loss in the first game of this series on Thursday. The Twins' bats have been ice cold, and it was no different in the first game of this series as they only put up two runs. Matt Wallner did have one hard-hit ball and also drove in one run. Joe Ryan also wasn’t good enough for his second straight start, going five innings and giving up five hits and four runs. 

The Twins are averaging 3.14 runs overall, while their defense is giving up 5.28 goals per game. This offense still has a lot of big-name bats in the lineup, but so far, they haven’t been good enough. Bailey Ober will get the start for the Twins. He has a 0-1 record and an ERA of 27.00. Against the St. Louis Cardinals, he went 2.2 innings, giving up seven hits and seven runs. 

Why the Twins Will Beat the Astros

• The Twins have won each of their last five day games against AL West opponents following a loss.
• The Astros have lost five of their last six games following a win.
• The Twins have covered the run line in each of their last four home games against AL West opponents following a home loss.
• The Astros have failed to cover the run line in five of their last six games.

Can Astros Move Back to .500? 

It’s early in the season, but the Astros are looking to move back to .500 with a victory in this game. On Thursday, the Astros actually fell behind 2-0, but that was the only real struggle for pitching, and they ended up cruising. Even if they won, the top four in the lineup had a grand total of four hits. Hunter Brown went six innings, giving up five hits and two earned runs. 

The Astros are averaging 2.43 runs per game, which isn’t shocking with the way the top of the lineup has performed so far this season. As a team, they are batting only .191, which is 27th in all of baseball. Hayden Wesneski could end up being activated before this game. Spencer Arrighettii is expected to get the start, and he sits with a 1-0 record and an ERA of 1.50. In his start against the New York Mets, he went six innings, giving up one hit and one run. 

Total Runs Facts

• Five of the Astros' last six road games have gone UNDER the total runs line.
• Nine of the Twins' last 12 games as home favorites have gone OVER the total runs line.
• The 'Inning 1 OVER 0.5 runs' market has hit in eight of the Twins' last nine day games.
• The 'Inning 1 UNDER 0.5 runs' market has hit in 10 of the Astros' last 12 day games.

Houston Astros vs Minnesota Twins Prediction

Give me the Minnesota Twins here. Sure, Bailey Ober struggled in his last start, but let’s not act like he’s a really good pitcher. Last season, he finished with a 12-9 record and an ERA of 3.98. Even though the Astros won on Thursday, the way the top of their lineup performed was a major issue, and they are going ot really struggle to get the offense going again here. The Twins' offense might not run up the score, but three or four runs will be enough to get the job done. Back the Astros.