Minnesota Twins vs Chicago White Sox Prediction 3/31/25 MLB Picks

In this article, we will formulate a Minnesota Twins vs Chicago White Sox prediction for this MLB game on Monday, March 31st at Rate Field in Chicago, Illinois. Let’s take a look at the prediction for this MLB matchup. 

Minnesota Twins Betting Preview

The Minnesota Twins are 0-3 this year after they were swept by St. Louis over the weekend by scores of 5-3, 5-1, and 9-2. Minnesota struggled with their pitching staff all weekend, while the offense was very inconsistent. In game three, the Twins took a 1-0 lead in the first inning on a single by Buxton, but they allowed eight runs in the second and third innings, which put the game away. Minnesota recorded just five hits in the game and was led by Buxton and Castro, who had one RBI each. The Twins started Bailey Ober, who allowed eight earned runs and eight hits over 2.2 innings, while Dobnak came on in relief and pitched the remaining 5.1 innings to eat up some innings. 

The Minnesota pitching staff has a 6.38 ERA with a 1.75 WHIP and a .306 opponent batting average, while their offense has scored six runs with a .167 batting average and a .208 on-base percentage this year. Willi Castro has led Minnesota through three games with one home run and three RBIs, while Harrison Bader has one home run and two RBIs on the season. The projected starting pitcher for Minnesota is Chris Paddack, who went 5-3 with a 4.99 ERA and a 1.39 WHIP over 88.1 innings pitched this year. 

Chicago White Sox Betting Preview

The Chicago White Sox are 1-2 this season after they lost two out of three games against the Angels to start the year. Chicago won game one by a score of 8-1 but lost games two and three by scores of 1-0 and 3-2. In game three, the White Sox were able to tie the game at two in the bottom of the first inning, but they went scoreless in the last eight innings for the loss. Chicago recorded seven hits in the game and was led by Maton, who went 1-3 with one home run and one RBI. The White Sox started Martin, who allowed four hits and zero earned runs, while Booser allowed one earned run and two hits in the eighth inning for the loss. 

The Chicago pitching staff has a 1.00 ERA with a 1.00 WHIP and a .202 opponent batting average, while the offense has scored 10 runs with a .196 batting average and a .260 on-base percentage this year. Andrew Benintendi has led Chicago with one home run and three RBIs, while Sosa and Vargas both have two RBIs each. The projected starting pitcher for Chicago is Martin Perez, who went 3-1 with a 3.46 ERA and a 1.21 WHIP over 52.0 innings with the Padres after getting traded from Pittsburgh last year. 

Why the White Sox will beat the Twins 

• The Twins have lost 10 of their last 11 games as favorites.
• The White Sox have won four of their last five games as home underdogs after playing the previous day.
• The White Sox have covered the run line in each of their last eight home games.
• The Twins have failed to cover the run line in each of their last seven games.
• The White Sox have led after 5 innings in four of their last five day games against the Twins.

Why the Twins will beat the White Sox

• The White Sox have lost each of their last 11 day games following a home loss.
• The Twins have won 13 of their last 14 games against the White Sox.
• The White Sox have failed to cover the run line in each of their last eight home games against AL Central opponents.
• The Twins have covered the run line in seven of their last eight games as favorites against the White Sox following a road loss.
• The Twins have led after 3 innings in 12 of their last 14 games as favorites against AL Central opponents.
• The White Sox have trailed after 5 innings in each of their last six Monday day games as home underdogs.

Total Runs Facts

• Six of the White Sox’s last seven day games after playing the previous day have gone UNDER the total runs line.
• Four of the Twins’ last five day games against AL Central opponents have gone UNDER the total runs line.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in 13 of the White Sox’s last 14 games.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in four of the Twins’ last five games.

Chicago White Sox Player Prop Facts

• Nick Maton has hit a home run in two of his last three home appearances after playing the previous day.
• Martin Perez has recorded a win in three of his last four appearances against AL opponents that held a losing record.
• Andrew Vaughn has recorded two RBIs in each of the White Sox’s last three home games against AL Central opponents that held a losing record.
• Andrew Benintendi has scored a run in five of his last six appearances at Rate Field against AL Central opponents that held a losing record.
• Andrew Benintendi has recorded at least one Single in each of his last six home appearances against opponents that held a losing record.
• Martin Perez has recorded four or more strikeouts in nine of his last 10 appearances against opponents that held a losing record.
• Andrew Benintendi has recorded at least one hit in each of his last eight appearances at Rate Field against opponents that held a losing record.

Minnesota Twins Player Prop Facts

• Carlos Correa has hit a home run in two of the Twins’ last three road games against the White Sox.
• Willi Castro has recorded a Double in each of the Twins’ last three games.
• Willi Castro has recorded an RBI in each of the Twins’ last four road games.
• Willi Castro has recorded at least one Single in each of his last seven Monday appearances against AL teams that held a losing record.
• Carlos Correa has recorded at least one hit in each of his last eight appearances against AL Central opponents that held a losing record.
• Trevor Larnach has scored at least one run in nine of his last 10 appearances with the Twins as favorites against the White Sox.

Minnesota Twins vs Chicago White Sox Prediction 

Both of these teams come into this matchup after struggling in their first series of the season, as Minnesota is looking for its first win. The Twins allowed 19 runs in three games against the Cardinals and will turn to Chris Paddack, who did not have a good 2024 season. Chicago started the season with an 8-1 win on Thursday, but they scored just two runs in the last two games, despite some very good pitching. I don’t love Martin Perez, and I think the Twins will jump on him early here. Take the over in this game.