Cleveland Guardians vs St. Louis Cardinals Prediction MLB Picks 9/22/24

St. Louis Cardinals (77-77) vs Cleveland Guardians (90-65)

Game Info: Sunday, September 22, 2024 at 2:15 pm (Busch Stadium)

Andre Pallante (7-8) (3.87) vs Gavin Williams (3-10) (5.12)

Betting Odds: St. Louis Cardinals -109 / Cleveland Guardians -109 --- Over/Under: Click Here for the Latest Odds

Where to Watch: BALLY Stream the MLB Game of the Day all season on ESPN+. Sign up now! Advertisement

The Cleveland Guardians and the St. Louis Cardinals meet Sunday in MLB action from Busch Stadium. Here’s a Cleveland Guardians vs St. Louis Cardinals prediction. This will be the final installment in a three-game series. We will look at this from a betting perspective and determine the best Guardians vs Cardinals pick. We will examine:

The Cleveland Guardians' recent form and player performance

The St. Louis Cardinals' recent form and player performance

Recent betting trends and streaks involving the Cleveland Guardians

Recent betting trends and streaks involving the St. Louis Cardinals

Recent betting trends in games played between the Guardians and Cardinals

A summary that ties it all together and produces a favorable betting outcome for the Guardians vs Cardinals game

Cleveland Guardians Betting Preview

Cleveland played the Minnesota Twins in their last set. The Guardians lost 4-1 Tuesday but won the other three games. Cleveland kept it going Friday with a 5-1 win over the Cardinals. On Saturday the Guardians took a tough loss 6-5.

In the starter slot for Sunday Cleveland is going with Gavin Williams. So far Williams is 3-10 with a 5.12 ERA in 15 starts. Over 31 career starts Williams is 6-15 with a 4.14 ERA.

St. Louis Cardinals Betting Preview

Over on the Cardinals’ side, they played the Pittsburgh Pirates in their last set. St. Louis won the first three games before a 3-2 loss Thursday. In Saturday’s matchup, the Cards were out-hit 10-8 in the win and gave up four runs in the eighth inning.

It’ll be Andre Pallante in the start for St. Louis on Sunday. This season Pallante is 7-8 with a 3.87 ERA in 27 games (18 starts). Over 136 career games (28 starts) Pallante is 17-14.

St. Louis Cardinals Player Prop Facts

  • Nolan Arenado has recorded at least one Single in each of the Cardinals' last six-day games against AL opponents that held a winning record.
  • Paul Goldschmidt has recorded at least one hit in each of his last 12 Sunday appearances against teams that held a winning record.
  • Paul Goldschmidt has recorded at least one total base in each of his last 12 Sunday appearances against teams that held a winning record.
  • Paul Goldschmidt has scored a run in five of his last six appearances in day games against AL Central teams that held a winning record.
  • Alec Burleson has hit a home run in three of the Cardinals' last six games at Busch Stadium against AL Central opponents that held a winning record.

Cleveland Guardians Player Prop Facts

  • Myles Straw has recorded at least one Single in nine of his last 10 road appearances against NL Central opponents.
  • Lane Thomas has recorded at least one hit in each of his last nine appearances against the Cardinals after playing the previous day.
  • Jose Ramirez has recorded at least one RBI in six of the Guardians' last seven games against the Cardinals.
  • Lane Thomas has recorded at least one total base in each of his last nine appearances against former teams.
  • Jose Ramirez has scored a run in each of the Guardians' last four road games.
  • Jose Ramirez has hit a home run in three of the Guardians' last four road games against the Cardinals.

Cleveland Guardians vs St. Louis Cardinals Prediction

I’ll probably stay with the Guardians. Also probably not touching it. Williams is on a rough run lately, going 0-3 in his last trio with 10 earned runs in 11.0 total innings. As for Pallante, he’s 1-2 in his last three with eight earned in 17.0 total frames.

On Saturday the Guardians nearly came back from a 6-1 hole but fell short of the epic evening. There were only two earned runs for Cleveland in this one, so the mound wasn’t exactly the trouble. I like the Guardians to come back from this one Sunday.

Andrew’s Pick Cleveland Guardians -109

Get Premium Picks Start Winning Now »
The pick in this article is the opinion of the writer, not a PickDawgz site consensus.

Mitch's Take...

NBA, NCAAF, NCAAB, NHL Best Bets for Today Picks & Predictions Friday 11/8/24 | 7 Picks in 5 Minutes

18+ Has gambling become a problem for you? Call the National Problem Gambling Hotline.
1-800-522-4700 | ncpgambling.org

Credit Guaranteed Packages

Packages with Credit Guarantees automatically give you a credit if the package does not turn a profit—the sum of betting all individual picks. THESE ARE NOT PARLAYS UNLESS OTHERWISE CLEARLY STATED. If a credit guaranteed package does not profit, a credit for its full purchase price is automatically issued after picks are graded and verified.

For example, if you purchase a $39.95 package that doesn’t profit, you’ll get a $39.95 credit towards any future purchase(s) on our site. Credits are usually issued within hours of a game’s conclusion, so please allow a few hours for final verification.

To use your credits, log in to your account and add another package or pass to your cart. Credits will automatically reduce what you owe. Any remaining balance will be settled through our payment system, with any leftover credits available future purchases. Credits do not expire.

Dismiss