Aug 3, 2024; Columbia, South Carolina, USA; Manchester United midfielder Casemiro (18) heads the ball against Liverpool in the second half at Williams-Brice Stadium. Mandatory Credit: Jeff Blake-Imagn Images

Manchester United vs Manchester City Prediction 9/14/2025 Today’s EPL Picks

Pick details

Manchester United (1-1-1) vs Manchester City (1-0-2)

September 14, 2025 at 11:30 AM EDT

The Line: Betting Odds: Manchester City -125 / Manchester United +310 — Over/Under: 3.5

(Get latest betting odds)

In this article, we will formulate a Manchester United vs Manchester City Prediction for this English Premier League Week 4 matchup on Sunday, September 14th, at the Etihad Stadium. Let’s take a look at the prediction for this English Premier League matchup.

Manchester City Preview

Manchester City has 3 points this season, with a 1-2-0 record, and are in 13th place in the Premier League standings. Manchester City is coming off a 1-2 road loss against Brighton, where they had 64% possession of the ball and 12 total shots, with 3 on goal. They completed 87% of their passes and had fewer expected goals, posting 1.82 compared to Brighton’s 2.29.

They have a 0-1 home record and a 1-1 road record this season, and they average 1.67 goals per game, while allowing 1.33 goals per game. Erling Haaland is the top scorer for Manchester City with total 3 goals this season in Premier League. Tijani Reijnders and Ryan Cherki follow with one goal each.

Manchester United Preview

Manchester United has 4 points this season, with a 1-1-1 record, and are in 9th place in the Premier League standings. Manchester United is coming off a 3-2 road win against Burnley, where they had 38% possession of the ball and 6 total shots, with 3 on goal. They completed 71% of their passes and had fewer expected goals, posting 1.20 compared to Burnley’s 3.63.

They have a 1-1 home record and a 0-0-1 road record this season, and they average 1.33 goals per game, while allowing 1.33 goals per game. Manchester United’s current top scorers are Bruno Fernandes and Mbeumo with 1 goal apiece.

Why Manchester City will win

·        Manchester City has won five of its last six EPL home matches.

·        Manchester City has won 29 of its last 38 EPL matches following a league loss.

·        Manchester City has won each of its last eight EPL Week 4 home matches.

·        Manchester City has won three of its last four EPL Sunday home matches against Manchester United.

·        Manchester City has won seven of its last 10 EPL matches.

·        Manchester City has won 21 of its last 24 EPL home matches following a league loss.

·        Manchester United has lost six of its last seven EPL matches following a league win.

·        Manchester United has lost four of its last six EPL away matches.

Total Points Facts

·        The ‘Both Teams to Score’ market has failed to hit in three of Manchester City’s last four EPL matches.

·        The ‘Both Teams to Score’ market has hit in seven of the last eight EPL matches between Manchester City and Manchester United at Etihad Stadium.

·        The ‘Over 2.5 Goals’ market has hit in seven of Manchester United’s last eight EPL matches at Etihad Stadium.

·        The ‘Over 3.5 Goals’ market has hit in four of Manchester City’s last five EPL day matches as a home favorite.

·        The ‘Over 2.5 Goals’ market has hit in six of the last seven EPL matches between Manchester City and Manchester United.

Manchester United vs Manchester City Prediction

In their two meetings last season, United won 2-1 on the road, while both teams had a 0-0 draw in Old Trafford. City is 5-2-1 in their last 8 overall meetings against United, and over is 6-1 in their last 7 meetings.

In this Manchester United vs Manchester City Prediction, Manchester City is coming as -125 road favorites. Both teams have been unimpressive to start the season, with City being winless at home and United winless on the road. City has back-to-back losses in the Premier League, while on the flip side, United has not lost in their two games following the defeat in their season opener. Given both team’s poor form, I like the guests to keep this one close, so take Manchester United by +0.5 goals in this one.

Nikos Lagouretos's Pick: Manchester United +0.5

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