San Francisco vs Colorado Prediction 11/27/2025 Today’s College Basketball Picks

In this article, we will formulate a Colorado vs San Francisco Prediction for this College Basketball game on Thursday, November 27th. Let’s take a look at the prediction for this College Basketball matchup.

San Francisco Dons Preview

San Francisco has a 5-1 record this season and are in the 5th place of the WCC conference. They are 3-2 ATS, 2-3 in Over/Under and have a 4-0 home record and a 0-1 away record. San Francisco is coming off a 77-65 neutral site win against Minnesota and will face North Alabama, Mississippi State and Saint Louis next.

Offensively, San Francisco averages 80.7 points per game, which ranks 157th in the nation, while defensively, they allow 65.3 points per game (50th). The Dons shoot with 48.3% from the field (78th), and with 41.2% from beyond the arc (17th). They shoot with 72.3% from the free throw line (146th), and grab 39.7 rebounds per game (95th), while dishing out 16.3 assists per game (105th) and committing 13.7 turnovers per game (256th).

Ryan Beasley leads San Francisco in scoring, with an average of 16 points and 3 assists per game. Mookie Cook follows with 13.3 points and 5.8 rebounds per game, while Tyrone Riley IV adds 11.2 points and 5 rebounds per game.

Colorado Buffaloes Preview

Colorado has a 5-0 record this season and are in the 3rd place of the Big 12 conference. They are 3-2 ATS, 5-0 in Over/Under and have a 5-0 home record and a 0-0 away record. Colorado is coming off a 95-79 home win against UC Davis and will face California Baptist, Colorado State and UTSA next.

Offensively, Colorado averages 94.4 points per game, which ranks 13th in the nation, while defensively, they allow 81.6 points per game (316th). The Buffaloes shoot with 53.4% from the field (8th), and with 42.2% from beyond the arc (10th). They shoot with 75.9% from the free throw line (61st), and grab 37 rebounds per game (203rd), while dishing out 19.0 assists per game (27th) and committing 10 turnovers per game (41st).

Isaiah Johnson and Sebastian Rancik lead Colorado in scoring, with an average of 14.8 points per game. Johnson adds 5.2 assists per game, while Rancik adds 6.2 rebounds per game. Alon Michaeli follows with 12.8 points and 4 rebounds per game.

San Francisco Dons @ Colorado Buffaloes Betting Trends: November 27, 2025

Why the Colorado Buffaloes will win

• Colorado has won 10 of its last 11 games against non-Conference opponents.
• San Francisco has lost four of its last five day games.
• Colorado has won the first half in each of its last four games.

Why the San Francisco Dons will win

• San Francisco has won each of its last four games.
• Colorado has lost three of its last four games against non-Conference opponents at neutral venues.
• Colorado has lost the first half in each of its last eight games played at neutral venues.

Total Points Facts

• Each of San Francisco’s last 17 games against non-Conference opponents have produced a total of 153 or fewer points.
• Fourteen of Colorado’s last 15 games against non-AP-ranked opponents at a neutral venue have produced a total of 149 or fewer points.

Colorado vs San Francisco Prediction

In this Colorado vs San Francisco Prediction, San Francisco is coming as -1.5 home favorites. Both teams have been excellent this season, as they have 5 wins each and Colorado has been undefeated so far.  Both teams have also been very good against the spread, having covered their three games each and both have been involved in some higher-scoring games lately, as they are a perfect 7-0 to the over in their last 7 games combined. They both average 175.1 points per game combined, with Colorado having the 13th-best offense in the country. Take the over 157 points in this one.

Nikos Lagouretos's Pick: Over 157