Nov 1, 2026; Rome, Italy;  Notre Dame Fighting Irish guard Braeden Smith (3) dribbles the ball up-court during the first half against the Villanova Wildcats at Palazzo dello Sport.  Mandatory Credit: Chris Jones-Imagn Images
IMAGN IMAGES via Reuters Connect

Mercyhurst vs Notre Dame Prediction 11/5/2026 Today’s College Basketball Picks

Pick details

Mercyhurst vs Notre Dame Odds and Matchup Info
MATCHUP Mercyhurst Lakers Notre Dame Fighting Irish
Team Records 0-1 1-0
Spread +19.5 -115 -19.5 -105
Moneyline +1600 -4000
Total Over 141.5 (-110) Under 141.5 (-110)
Where Purcell Pavilion, South Bend, IN
When Thursday, November 5, 2026
Time 07:00 PM EST
TV ACCNX

The Mercyhurst Lakers and the Notre Dame Fighting Irish meet Thursday in college basketball action from the Purcell Pavilion. We will look at this from a betting perspective and determine the best bets for this game. 

Mercyhurst Lakers vs. Notre Dame Fighting Irish Prediction

I’m on Mercyhurst and the points here. I’m still not 100% sold on what Notre Dame’s brought to the table and while the win over Villanova is great, it’s still an international travel spot and an Irish team that’s heard everyone’s hype about that win over the last couple of days. I think Mercyhurst could humble the Irish here a little, as they’re a veteran lineup that will relish the opportunity to take on the Irish here. Give me Mercyhurst and the points.

Mercyhurst Lakers Recap

The Mercyhurst Lakers come into this game looking to rebound from a 78-43 loss at the hands of Marquette last time out to sit at 0-1 this season. After this game, Mercyhurst will have a home game against subdivision Penn State Shenango. Jake Lemelman has 16.0 PPG with 2.0 RPG and 2.0 APG to lead the Lakers in scoring while Hunter Te Ratana has 8.0 PPG with 1.0 RPG. Markus Maxwell-Grimes has 7.0 PPG with 2.0 RPG and 2.0 APG, Cameron Johnson has 6.0 PPG, Geoff Sprouse has 2.0 PPG with 3.0 RPG and a team-high 3.0 APG to lead the Lakers in assists, Chris Leman has 2.0 PPG with 2.0 RPG, and Shane Kirker has 2.0 PPG with 1.0 RPG and 1.0 APG as well this season. Deraje Agbaosi leads the Lakers in rebounding with a team-high 6.0 RPG this season. As a team, Mercyhurst is averaging 43.0 PPG on 29.3% shooting from the field, 14.8% from three and 71.4% from the foul line this season.

Why the Mercyhurst Lakers will win

  • Notre Dame has lost each of its last six night games.
  • Notre Dame has lost the first half in seven of its last eight night games.

Notre Dame Fighting Irish Recap

The Notre Dame Fighting Irish come into this game looking to add on to their 74-72 win over Villanova last time out to sit at 1-0 this season. After this game, Notre Dame will square off against Eastern Illinois at home. Braeden Smith has 16.0 PPG with 4.0 RPG and 3.0 APG while Brady Koehler has 16.0 PPG with a team-high 8.0 RPG to lead the Fighting Irish in rebounding alongside 1.0 APG. Braeden Shrewsberry has 15.0 PPG with 6.0 RPG and 3.0 APG, while Ethan Roberts has 11.0 PPG with 2.0 RPG to cap off the group of double-digit scorers for Notre Dame. Logan Duncomb has 9.0 PPG with 3.0 RPG and a team-high 4.0 APG to lead the Fighting Irish in assists, Tommy Ahneman has 4.0 PPG with 6.0 RPG, and Jonathan Sanderson has 3.0 PPG with 1.0 RPG and 2.0 APG as well this season. As a team, Notre Dame is averaging 74.0 PPG on 35.4% shooting from the field, 37.5% from three and 76.0% from the foul line this season.

Why the Notre Dame Fighting Irish will win

  • Notre Dame has won each of its last nine night games against non-Conference opponents.
  • Mercyhurst has lost each of its last eight road games against non-Conference opponents.
  • Mercyhurst has lost the first half in seven of its last eight road games against non-Conference opponents.

Chris Ruffolo's Pick: Mercyhurst +19.5

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