Loyola Chicago vs Santa Clara Prediction 12/20/2025 Today’s College Basketball Picks

The Loyola Chicago Ramblers and the Santa Clara Broncos meet Wednesday in college basketball action from the Kaiser Permanente Arena. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Loyola Chicago Ramblers vs. Santa Clara Broncos prediction.

Loyola Chicago Ramblers Recap

The Loyola Chicago Ramblers come into this game looking to bounce back from their 85-71 loss at the hands of San Francisco last time out to sit at 3-9 this season. After this game, Loyola Chicago will head on the road for a game against Rhode Island.

Ramblers Drop Back-To-Back Games

Miles Rubin leads the Ramblers in scoring and rebounding with 12.2 PPG and 7.1 RPG while Justin Moore has 12 PPG with 2.5 RPG and a team-high 4.8 APG to lead the Ramblers in assists. Deywilk Tavarez has 11.2 PPG with 2.7 RPG to cap off the group of double-digit scorers for Loyola-Chicago so far this season. Kayde Dotson has 8.5 PPG with 2.5 RPG while Chuck Love has 8.4 PPG with 2.8 RPG as well on the year. As a team, Loyola Chicago is averaging 68.3 PPG on 41.4% shooting from the field, 32.7% from three and 69% from the foul line this season. 

Santa Clara Broncos Recap

The Santa Clara Broncos come into this game looking to add on to their 63-60 win over North Texas last time out to sit at 9-3 on the year. After this game, Santa Clara will head on the road for a game against Oregon State.

Broncos Snap Two-Game Slide

Christian Hammond leads the Broncos in scoring with 16.6 PPG along with 3.5 RPG and 2.5 APG while Elijah Mahi has 13.8 PPG with 4.8 RPG and 2.6 APG as the only other double-digit scorer for Santa Clara so far this season. Bukky Oboye has 9.3 PPG with 3.6 RPG and Allen Graves has 8.8 PPG with 6.3 RPG and 2.1 APG. Brenton Knapper has 7.5 PPG with 3.1 APG and Sash Gavalyugov has 7.3 PPG with 2.3 RPG and 2.7 APG. Jake Ensminger also has 6.9 PPG with 6.6 RPG and 3.8 APG to lead Santa Clara in rebounding and assists so far this season. As a team, Santa Clara is averaging 79.2 PPG on 45% shooting from the field, 31.2% from three and 67.7% from the foul line so far this season.

Loyola Chicago Ramblers vs. Santa Clara Broncos Prediction

I’m on Santa Clara here. I think the Broncos are the better team by a mile here and maybe it’s a fade of Loyola Chicago more than anything else but the thing here is that the Ramblers have not given anyone any reason to think that they’ll be able to compete in this game. The Broncos haven’t been blowing away inferior teams this season but I think they’re good enough here to get the job done for the win and cover against a Ramblers team that could be checked out on the season. Give me Santa Clara here.

Chris Ruffolo's Pick: Santa Clara -17.5