Roughriders vs Lions Prediction 9/25/2026 Today’s CFL Picks

In this article we will formulate a Roughriders vs Lions prediction for this CFL game on Friday, September 25th at BC Place in Vancouver, British Columbia. Let’s take a look at the prediction for this CFL matchup.

Saskatchewan Roughriders Betting Preview

The Saskatchewan Roughriders are 8-5 this year after they lost to the Blue Bombers by a score of 19-6 in their last game. Saskatchewan cut the deficit to 10-3 at halftime, but they only managed three points in the second half for the disappointing loss. The Roughriders were out gained by a total of 291-278, went 4-22 on second downs, and lost the turnover battle by a total of 5-2 in the game. Harris threw for 231 yards and one interception, while Duncan-Busby caught seven passes for 80 yards. Conley rushed seven times for 35 yards in the loss. 

Prior to that game, Saskatchewan defeated the Blue Bombers by a score of 32-26 and defeated the Argonauts by a score of 28-24, and they are currently second in the West Division. The Roughriders have scored 28.8 points per game with 317.2 passing yards and 93.2 rushing yards per game, while they have allowed 26.2 points against per game this season. Trevor Harris has thrown for 4,124 yards with 24 touchdowns and 12 interceptions this year. 

BC Lions Betting Preview

The BC Lions are 7-6 this season after they defeated the Alouettes by a score of 48-29 in their last game. BC led 31-23 at halftime and they only allowed six points in the second half for the big win. The Lions out gained Montreal by a total of 429-333, went 11-21 on second downs, and won the turnover battle by a total of 2-1 in the game. Rourke threw for 317 yards and one touchdown, while Hatcher caught nine passes for 137 yards and one score. Rourke also led the rushing attack with 77 yards and one touchdown on five carries in the win. 

Prior to that game, BC lost to the Alouettes by a score of 37-30 and defeated the Redblacks by a score of 45-24, and they are currently third in the West Division. The Lions have scored 30.5 points per game with 322.5 passing yards and 121.3 rushing yards per game, while they have allowed 27.5 points against per game this season. Nathan Rourke has thrown for 3,476 yards with 16 touchdowns and 10 interceptions this season. 

Roughriders vs Lions Prediction 

BC rolls into this matchup after winning four of their last five games and they have scored 30+ points in five straight. The Lions are playing great football right now and Rourke has the offense humming. Saskatchewan has lost three of their last five games and their offense is struggling. The Roughriders are better than how they are playing right now, but I can’t go against BC in this form. Take the Lions to win and cover here.

David Racey's Pick: Lions -3